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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMU1
Full Name:
WD40 repeat-containing protein SMU1
Alias:
WD40 repeat-containing protein SMU1
Type:
Mass (Da):
57526
Number AA:
513
UniProt ID:
Q2TAY7
International Prot ID:
IPI00305833
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
V
I
R
L
I
M
Q
Y
L
K
E
N
S
L
H
Site 2
S37
L
Q
E
E
T
T
V
S
L
N
T
V
D
S
I
Site 3
T40
E
T
T
V
S
L
N
T
V
D
S
I
E
S
F
Site 4
S46
N
T
V
D
S
I
E
S
F
V
A
D
I
N
S
Site 5
T58
I
N
S
G
H
W
D
T
V
L
Q
A
I
Q
S
Site 6
S65
T
V
L
Q
A
I
Q
S
L
K
L
P
D
K
T
Site 7
T72
S
L
K
L
P
D
K
T
L
I
D
L
Y
E
Q
Site 8
S95
R
E
L
G
A
A
R
S
L
L
R
Q
T
D
P
Site 9
T100
A
R
S
L
L
R
Q
T
D
P
M
I
M
L
K
Site 10
Y114
K
Q
T
Q
P
E
R
Y
I
H
L
E
N
L
L
Site 11
Y125
E
N
L
L
A
R
S
Y
F
D
P
R
E
A
Y
Site 12
Y132
Y
F
D
P
R
E
A
Y
P
D
G
S
S
K
E
Site 13
T203
V
E
E
E
K
F
P
T
Q
L
S
R
H
I
K
Site 14
S206
E
K
F
P
T
Q
L
S
R
H
I
K
F
G
Q
Site 15
S215
H
I
K
F
G
Q
K
S
H
V
E
C
A
R
F
Site 16
S223
H
V
E
C
A
R
F
S
P
D
G
Q
Y
L
V
Site 17
Y228
R
F
S
P
D
G
Q
Y
L
V
T
G
S
V
D
Site 18
T245
I
E
V
W
N
F
T
T
G
K
I
R
K
D
L
Site 19
Y254
K
I
R
K
D
L
K
Y
Q
A
Q
D
N
F
M
Site 20
T281
R
D
T
E
M
L
A
T
G
A
Q
D
G
K
I
Site 21
S307
R
R
F
E
R
A
H
S
K
G
V
T
C
L
S
Site 22
T311
R
A
H
S
K
G
V
T
C
L
S
F
S
K
D
Site 23
S314
S
K
G
V
T
C
L
S
F
S
K
D
S
S
Q
Site 24
S319
C
L
S
F
S
K
D
S
S
Q
I
L
S
A
S
Site 25
S320
L
S
F
S
K
D
S
S
Q
I
L
S
A
S
F
Site 26
S324
K
D
S
S
Q
I
L
S
A
S
F
D
Q
T
I
Site 27
S326
S
S
Q
I
L
S
A
S
F
D
Q
T
I
R
I
Site 28
T330
L
S
A
S
F
D
Q
T
I
R
I
H
G
L
K
Site 29
S338
I
R
I
H
G
L
K
S
G
K
T
L
K
E
F
Site 30
T341
H
G
L
K
S
G
K
T
L
K
E
F
R
G
H
Site 31
S349
L
K
E
F
R
G
H
S
S
F
V
N
E
A
T
Site 32
S350
K
E
F
R
G
H
S
S
F
V
N
E
A
T
F
Site 33
T356
S
S
F
V
N
E
A
T
F
T
Q
D
G
H
Y
Site 34
T358
F
V
N
E
A
T
F
T
Q
D
G
H
Y
I
I
Site 35
Y363
T
F
T
Q
D
G
H
Y
I
I
S
A
S
S
D
Site 36
S366
Q
D
G
H
Y
I
I
S
A
S
S
D
G
T
V
Site 37
T372
I
S
A
S
S
D
G
T
V
K
I
W
N
M
K
Site 38
S384
N
M
K
T
T
E
C
S
N
T
F
K
S
L
G
Site 39
T386
K
T
T
E
C
S
N
T
F
K
S
L
G
S
T
Site 40
S389
E
C
S
N
T
F
K
S
L
G
S
T
A
G
T
Site 41
S434
M
Q
G
Q
I
V
R
S
F
S
S
G
K
R
E
Site 42
S436
G
Q
I
V
R
S
F
S
S
G
K
R
E
G
G
Site 43
S437
Q
I
V
R
S
F
S
S
G
K
R
E
G
G
D
Site 44
Y458
S
P
R
G
E
W
I
Y
C
V
G
E
D
F
V
Site 45
T481
G
K
L
E
R
T
L
T
V
H
E
K
D
V
I
Site 46
S503
Q
N
L
I
A
T
Y
S
E
D
G
L
L
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation