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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MUM1
Full Name:
PWWP domain-containing protein MUM1
Alias:
melanoma associated antigen (mutated) 1; melanoma ubiquitous mutated; MUM-1
Type:
Cell surface
Mass (Da):
78636
Number AA:
710
UniProt ID:
Q2TAK8
International Prot ID:
IPI00383594
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
A
D
A
K
Y
V
L
C
R
W
E
K
Site 2
T26
K
V
L
A
R
T
A
T
S
T
K
N
K
R
R
Site 3
T28
L
A
R
T
A
T
S
T
K
N
K
R
R
K
E
Site 4
Y36
K
N
K
R
R
K
E
Y
F
L
A
V
Q
I
L
Site 5
S53
E
E
K
I
K
V
K
S
T
E
V
E
I
L
E
Site 6
S62
E
V
E
I
L
E
K
S
Q
I
E
A
I
A
S
Site 7
S69
S
Q
I
E
A
I
A
S
S
L
A
S
Q
N
E
Site 8
S70
Q
I
E
A
I
A
S
S
L
A
S
Q
N
E
V
Site 9
Y87
A
P
L
E
E
L
A
Y
R
R
S
L
R
V
A
Site 10
S90
E
E
L
A
Y
R
R
S
L
R
V
A
L
D
V
Site 11
S102
L
D
V
L
S
E
G
S
I
W
S
Q
E
S
S
Site 12
S105
L
S
E
G
S
I
W
S
Q
E
S
S
A
G
T
Site 13
S108
G
S
I
W
S
Q
E
S
S
A
G
T
G
R
A
Site 14
S109
S
I
W
S
Q
E
S
S
A
G
T
G
R
A
D
Site 15
T112
S
Q
E
S
S
A
G
T
G
R
A
D
R
S
L
Site 16
S118
G
T
G
R
A
D
R
S
L
R
G
K
P
M
E
Site 17
S128
G
K
P
M
E
H
V
S
S
P
C
D
S
N
S
Site 18
S129
K
P
M
E
H
V
S
S
P
C
D
S
N
S
S
Site 19
S133
H
V
S
S
P
C
D
S
N
S
S
S
L
P
R
Site 20
S135
S
S
P
C
D
S
N
S
S
S
L
P
R
G
D
Site 21
S137
P
C
D
S
N
S
S
S
L
P
R
G
D
V
L
Site 22
S146
P
R
G
D
V
L
G
S
S
R
P
H
R
R
R
Site 23
S159
R
R
P
C
V
Q
Q
S
L
S
S
S
F
T
C
Site 24
S161
P
C
V
Q
Q
S
L
S
S
S
F
T
C
E
K
Site 25
S163
V
Q
Q
S
L
S
S
S
F
T
C
E
K
D
P
Site 26
T165
Q
S
L
S
S
S
F
T
C
E
K
D
P
E
C
Site 27
S183
H
K
K
G
L
R
K
S
E
N
P
R
G
P
L
Site 28
S202
G
G
G
A
Q
D
E
S
G
S
R
I
H
H
K
Site 29
T212
R
I
H
H
K
N
W
T
L
A
S
K
R
G
G
Site 30
S215
H
K
N
W
T
L
A
S
K
R
G
G
N
S
A
Site 31
S221
A
S
K
R
G
G
N
S
A
Q
K
A
S
L
C
Site 32
S226
G
N
S
A
Q
K
A
S
L
C
L
N
G
S
S
Site 33
S232
A
S
L
C
L
N
G
S
S
L
S
E
D
D
T
Site 34
S233
S
L
C
L
N
G
S
S
L
S
E
D
D
T
E
Site 35
S235
C
L
N
G
S
S
L
S
E
D
D
T
E
R
D
Site 36
T239
S
S
L
S
E
D
D
T
E
R
D
M
G
S
K
Site 37
S245
D
T
E
R
D
M
G
S
K
G
G
S
W
A
A
Site 38
S249
D
M
G
S
K
G
G
S
W
A
A
P
S
L
P
Site 39
S254
G
G
S
W
A
A
P
S
L
P
S
G
V
R
E
Site 40
S279
D
P
G
L
P
L
G
S
L
T
A
P
P
A
P
Site 41
T281
G
L
P
L
G
S
L
T
A
P
P
A
P
E
P
Site 42
S289
A
P
P
A
P
E
P
S
A
C
S
E
P
G
E
Site 43
S308
K
R
P
R
L
D
G
S
Q
R
P
P
A
V
Q
Site 44
S326
M
A
A
G
A
A
P
S
P
G
P
G
P
G
P
Site 45
S336
P
G
P
G
P
R
E
S
V
T
P
R
S
T
A
Site 46
T338
P
G
P
R
E
S
V
T
P
R
S
T
A
R
L
Site 47
S341
R
E
S
V
T
P
R
S
T
A
R
L
G
P
P
Site 48
T342
E
S
V
T
P
R
S
T
A
R
L
G
P
P
P
Site 49
S350
A
R
L
G
P
P
P
S
H
A
S
A
D
A
T
Site 50
S353
G
P
P
P
S
H
A
S
A
D
A
T
R
C
L
Site 51
T357
S
H
A
S
A
D
A
T
R
C
L
P
C
P
D
Site 52
S365
R
C
L
P
C
P
D
S
Q
K
L
E
K
E
C
Site 53
S374
K
L
E
K
E
C
Q
S
S
E
E
S
M
G
S
Site 54
S375
L
E
K
E
C
Q
S
S
E
E
S
M
G
S
N
Site 55
S378
E
C
Q
S
S
E
E
S
M
G
S
N
S
M
R
Site 56
S381
S
S
E
E
S
M
G
S
N
S
M
R
S
I
L
Site 57
S383
E
E
S
M
G
S
N
S
M
R
S
I
L
E
E
Site 58
Y403
E
P
P
R
V
L
L
Y
H
E
P
R
S
F
E
Site 59
S431
F
W
P
A
V
V
K
S
V
R
Q
R
D
K
K
Site 60
S440
R
Q
R
D
K
K
A
S
V
L
Y
I
E
G
H
Site 61
Y443
D
K
K
A
S
V
L
Y
I
E
G
H
M
N
P
Site 62
S458
K
M
K
G
F
T
V
S
L
K
S
L
K
H
F
Site 63
S461
G
F
T
V
S
L
K
S
L
K
H
F
D
C
K
Site 64
Y512
A
G
S
F
L
E
Y
Y
A
A
D
I
S
Y
P
Site 65
S517
E
Y
Y
A
A
D
I
S
Y
P
V
R
K
S
I
Site 66
Y518
Y
Y
A
A
D
I
S
Y
P
V
R
K
S
I
Q
Site 67
S523
I
S
Y
P
V
R
K
S
I
Q
Q
D
V
L
G
Site 68
S537
G
T
K
L
P
Q
L
S
K
G
S
P
E
E
P
Site 69
S540
L
P
Q
L
S
K
G
S
P
E
E
P
V
V
G
Site 70
S564
R
K
M
L
P
D
R
S
R
A
A
R
D
R
A
Site 71
S587
V
K
A
K
G
A
E
S
H
L
R
A
I
L
K
Site 72
S595
H
L
R
A
I
L
K
S
R
K
P
S
R
W
L
Site 73
S599
I
L
K
S
R
K
P
S
R
W
L
Q
T
F
L
Site 74
T604
K
P
S
R
W
L
Q
T
F
L
S
S
S
Q
Y
Site 75
S607
R
W
L
Q
T
F
L
S
S
S
Q
Y
V
T
C
Site 76
T613
L
S
S
S
Q
Y
V
T
C
V
E
T
Y
L
E
Site 77
Y618
Y
V
T
C
V
E
T
Y
L
E
D
E
G
Q
L
Site 78
Y631
Q
L
D
L
V
V
K
Y
L
Q
G
V
Y
Q
E
Site 79
Y636
V
K
Y
L
Q
G
V
Y
Q
E
V
G
A
K
V
Site 80
Y676
S
A
V
D
E
V
D
Y
K
T
A
E
E
K
Y
Site 81
T678
V
D
E
V
D
Y
K
T
A
E
E
K
Y
I
K
Site 82
S688
E
K
Y
I
K
G
P
S
L
S
Y
R
E
K
E
Site 83
S690
Y
I
K
G
P
S
L
S
Y
R
E
K
E
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation