KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CCDC57
Full Name:
Coiled-coil domain-containing protein 57
Alias:
Type:
Mass (Da):
103199
Number AA:
916
UniProt ID:
Q2TAC2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S41
A
A
L
Q
D
T
R
S
Q
L
E
E
A
Q
G
Site 2
Y59
C
L
Q
E
D
F
V
Y
N
L
Q
V
L
E
E
Site 3
Y74
R
D
L
E
L
E
R
Y
D
A
A
F
A
Q
A
Site 4
S93
E
A
R
R
A
E
V
S
E
L
K
I
E
A
A
Site 5
S136
L
E
L
E
R
V
H
S
D
K
N
G
E
I
D
Site 6
Y149
I
D
H
H
R
E
Q
Y
E
N
L
K
W
T
L
Site 7
S180
E
L
L
L
E
F
E
S
K
M
R
K
R
E
H
Site 8
S197
R
L
Q
A
D
N
M
S
N
T
A
L
S
R
E
Site 9
S227
A
G
A
K
A
A
E
S
L
Q
R
A
E
A
T
Site 10
S269
D
L
E
D
K
L
H
S
V
Q
L
T
R
K
K
Site 11
T273
K
L
H
S
V
Q
L
T
R
K
K
E
E
E
T
Site 12
T280
T
R
K
K
E
E
E
T
F
K
R
K
H
E
E
Site 13
S357
D
Q
L
R
E
D
A
S
T
V
K
S
A
W
D
Site 14
T358
Q
L
R
E
D
A
S
T
V
K
S
A
W
D
A
Site 15
S361
E
D
A
S
T
V
K
S
A
W
D
A
Q
I
A
Site 16
S371
D
A
Q
I
A
Q
L
S
K
E
M
V
S
R
D
Site 17
S398
L
K
A
Q
V
A
R
S
Q
Q
D
I
E
R
Y
Site 18
S410
E
R
Y
K
Q
Q
L
S
L
A
V
E
R
E
R
Site 19
S418
L
A
V
E
R
E
R
S
L
E
R
D
Q
V
Q
Site 20
S445
E
R
D
Q
I
Q
K
S
E
A
L
I
Q
G
L
Site 21
S453
E
A
L
I
Q
G
L
S
M
A
K
S
Q
V
A
Site 22
S457
Q
G
L
S
M
A
K
S
Q
V
A
A
K
L
Q
Site 23
S513
R
Q
H
E
E
E
I
S
K
D
F
P
S
S
E
Site 24
S518
E
I
S
K
D
F
P
S
S
E
I
Q
R
L
R
Site 25
S519
I
S
K
D
F
P
S
S
E
I
Q
R
L
R
E
Site 26
S530
R
L
R
E
Q
N
T
S
L
R
N
A
I
A
Q
Site 27
S546
R
K
E
M
E
A
L
S
H
Q
I
P
P
P
I
Site 28
T595
T
L
K
H
K
F
K
T
L
E
K
H
L
E
D
Site 29
S610
V
L
D
P
L
K
M
S
S
P
H
A
E
S
Q
Site 30
S611
L
D
P
L
K
M
S
S
P
H
A
E
S
Q
P
Site 31
S616
M
S
S
P
H
A
E
S
Q
P
S
V
R
T
S
Site 32
S619
P
H
A
E
S
Q
P
S
V
R
T
S
T
E
T
Site 33
T622
E
S
Q
P
S
V
R
T
S
T
E
T
T
G
G
Site 34
S623
S
Q
P
S
V
R
T
S
T
E
T
T
G
G
S
Site 35
T624
Q
P
S
V
R
T
S
T
E
T
T
G
G
S
A
Site 36
T626
S
V
R
T
S
T
E
T
T
G
G
S
A
Q
A
Site 37
S639
Q
A
G
Q
A
G
G
S
V
Q
A
G
Q
A
G
Site 38
S648
Q
A
G
Q
A
G
G
S
V
Q
A
G
P
V
S
Site 39
S655
S
V
Q
A
G
P
V
S
S
G
L
A
L
R
K
Site 40
S731
Q
H
G
G
A
E
P
S
G
R
K
Q
P
P
A
Site 41
S739
G
R
K
Q
P
P
A
S
D
A
V
A
L
G
R
Site 42
S752
G
R
E
Q
D
A
K
S
A
E
D
E
A
P
S
Site 43
S769
L
G
K
H
Q
P
R
S
A
Q
V
G
S
R
L
Site 44
T784
D
A
L
Q
G
P
K
T
Q
H
S
I
H
T
V
Site 45
T790
K
T
Q
H
S
I
H
T
V
T
C
K
S
P
R
Site 46
S795
I
H
T
V
T
C
K
S
P
R
Q
K
E
D
R
Site 47
S803
P
R
Q
K
E
D
R
S
P
K
P
P
Q
A
P
Site 48
S820
P
E
E
H
G
R
Q
S
H
S
S
S
S
F
A
Site 49
S822
E
H
G
R
Q
S
H
S
S
S
S
F
A
S
G
Site 50
S823
H
G
R
Q
S
H
S
S
S
S
F
A
S
G
T
Site 51
S824
G
R
Q
S
H
S
S
S
S
F
A
S
G
T
L
Site 52
S825
R
Q
S
H
S
S
S
S
F
A
S
G
T
L
Q
Site 53
S828
H
S
S
S
S
F
A
S
G
T
L
Q
D
M
W
Site 54
T830
S
S
S
F
A
S
G
T
L
Q
D
M
W
R
L
Site 55
S842
W
R
L
L
D
L
G
S
S
P
S
G
V
T
S
Site 56
S843
R
L
L
D
L
G
S
S
P
S
G
V
T
S
Q
Site 57
S845
L
D
L
G
S
S
P
S
G
V
T
S
Q
G
D
Site 58
S849
S
S
P
S
G
V
T
S
Q
G
D
S
T
P
E
Site 59
S853
G
V
T
S
Q
G
D
S
T
P
E
L
P
A
P
Site 60
T854
V
T
S
Q
G
D
S
T
P
E
L
P
A
P
P
Site 61
T876
K
M
Q
A
G
I
A
T
P
G
M
K
T
A
A
Site 62
T889
A
A
Q
A
K
A
K
T
T
G
A
S
R
S
H
Site 63
T890
A
Q
A
K
A
K
T
T
G
A
S
R
S
H
P
Site 64
S895
K
T
T
G
A
S
R
S
H
P
A
K
A
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation