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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSR1
Full Name:
Pre-rRNA-processing protein TSR1 homolog
Alias:
FLJ10534; pre-rRNA-processing protein TSR1; TSR1, 20S rRNA accumulation; TSR1, 20S rRNA accumulation,
Type:
Mass (Da):
91792
Number AA:
804
UniProt ID:
Q2NL82
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0042255
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
G
R
H
R
G
R
G
S
A
Q
R
D
G
K
G
Site 2
T39
K
G
R
L
A
L
K
T
L
S
K
K
V
R
K
Site 3
S41
R
L
A
L
K
T
L
S
K
K
V
R
K
E
L
Site 4
S49
K
K
V
R
K
E
L
S
R
V
D
Q
R
H
R
Site 5
S58
V
D
Q
R
H
R
A
S
Q
L
R
K
Q
K
K
Site 6
T108
Q
L
L
Q
D
R
D
T
G
T
V
H
L
N
E
Site 7
T110
L
Q
D
R
D
T
G
T
V
H
L
N
E
L
G
Site 8
S168
D
P
L
E
G
W
D
S
T
G
D
Y
C
L
S
Site 9
T169
P
L
E
G
W
D
S
T
G
D
Y
C
L
S
C
Site 10
S208
I
D
T
R
K
K
L
S
K
A
V
E
K
R
F
Site 11
T225
D
K
L
L
L
L
D
T
Q
Q
E
A
G
M
L
Site 12
Y252
A
F
R
D
R
R
A
Y
L
F
A
H
A
V
D
Site 13
T271
E
E
N
N
L
V
G
T
L
K
I
S
G
Y
V
Site 14
Y277
G
T
L
K
I
S
G
Y
V
R
G
Q
T
L
N
Site 15
T282
S
G
Y
V
R
G
Q
T
L
N
V
N
R
L
L
Site 16
Y294
R
L
L
H
I
V
G
Y
G
D
F
Q
M
K
Q
Site 17
S354
A
D
P
G
R
Q
E
S
L
Q
A
E
V
I
P
Site 18
T369
D
P
M
E
G
E
Q
T
W
P
T
E
E
E
L
Site 19
T372
E
G
E
Q
T
W
P
T
E
E
E
L
S
E
A
Site 20
S377
W
P
T
E
E
E
L
S
E
A
K
D
F
L
K
Site 21
S410
E
W
I
L
D
G
G
S
Q
S
G
G
E
G
D
Site 22
Y419
S
G
G
E
G
D
E
Y
E
Y
D
D
M
E
H
Site 23
Y421
G
E
G
D
E
Y
E
Y
D
D
M
E
H
E
D
Site 24
S434
E
D
F
M
E
E
E
S
Q
D
E
S
S
E
E
Site 25
S438
E
E
E
S
Q
D
E
S
S
E
E
E
E
E
Y
Site 26
S439
E
E
S
Q
D
E
S
S
E
E
E
E
E
Y
E
Site 27
Y445
S
S
E
E
E
E
E
Y
E
T
M
T
I
G
E
Site 28
T447
E
E
E
E
E
Y
E
T
M
T
I
G
E
S
V
Site 29
T449
E
E
E
Y
E
T
M
T
I
G
E
S
V
H
D
Site 30
S453
E
T
M
T
I
G
E
S
V
H
D
D
L
Y
D
Site 31
Y459
E
S
V
H
D
D
L
Y
D
K
K
V
D
E
E
Site 32
Y475
E
A
K
M
L
E
K
Y
K
Q
E
R
L
E
E
Site 33
T490
M
F
P
D
E
V
D
T
P
R
D
V
A
A
R
Site 34
Y503
A
R
I
R
F
Q
K
Y
R
G
L
K
S
F
R
Site 35
S508
Q
K
Y
R
G
L
K
S
F
R
T
S
P
W
D
Site 36
T511
R
G
L
K
S
F
R
T
S
P
W
D
P
K
E
Site 37
S512
G
L
K
S
F
R
T
S
P
W
D
P
K
E
N
Site 38
Y524
K
E
N
L
P
Q
D
Y
A
R
I
F
Q
F
Q
Site 39
S539
N
F
T
N
T
R
K
S
I
F
K
E
V
E
E
Site 40
Y557
E
G
A
E
V
G
W
Y
V
T
L
H
V
S
E
Site 41
S583
G
T
P
L
I
A
F
S
L
L
P
H
E
Q
K
Site 42
S592
L
P
H
E
Q
K
M
S
V
L
N
M
V
V
R
Site 43
T605
V
R
R
D
P
G
N
T
E
P
V
K
A
K
E
Site 44
S626
G
F
R
R
F
R
A
S
P
L
F
S
Q
H
T
Site 45
S630
F
R
A
S
P
L
F
S
Q
H
T
A
A
D
K
Site 46
S677
Q
K
S
N
G
M
H
S
L
I
A
T
G
H
L
Site 47
T747
H
I
K
E
P
L
G
T
H
G
H
M
K
C
S
Site 48
S754
T
H
G
H
M
K
C
S
F
D
G
K
L
K
S
Site 49
S761
S
F
D
G
K
L
K
S
Q
D
T
V
L
M
N
Site 50
T764
G
K
L
K
S
Q
D
T
V
L
M
N
L
Y
K
Site 51
Y770
D
T
V
L
M
N
L
Y
K
R
V
F
P
K
W
Site 52
T778
K
R
V
F
P
K
W
T
Y
D
P
Y
V
P
E
Site 53
Y779
R
V
F
P
K
W
T
Y
D
P
Y
V
P
E
P
Site 54
Y782
P
K
W
T
Y
D
P
Y
V
P
E
P
V
P
W
Site 55
S792
E
P
V
P
W
L
K
S
E
I
S
S
T
V
P
Site 56
S795
P
W
L
K
S
E
I
S
S
T
V
P
Q
G
G
Site 57
S796
W
L
K
S
E
I
S
S
T
V
P
Q
G
G
M
Site 58
T797
L
K
S
E
I
S
S
T
V
P
Q
G
G
M
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation