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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD43
Full Name:
Ankyrin repeat domain-containing protein 43
Alias:
ankyrin repeat domain 43; ankyrin repeat domain-containing 43; ANR43
Type:
Mass (Da):
57410
Number AA:
UniProt ID:
Q2M3V2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
H
G
G
K
V
R
N
S
E
L
L
S
R
F
K
Site 2
S37
V
R
N
S
E
L
L
S
R
F
K
P
L
L
D
Site 3
S103
P
G
A
A
A
Q
P
S
K
P
T
S
T
V
L
Site 4
S107
A
Q
P
S
K
P
T
S
T
V
L
P
R
S
A
Site 5
T108
Q
P
S
K
P
T
S
T
V
L
P
R
S
A
S
Site 6
S113
T
S
T
V
L
P
R
S
A
S
A
P
G
A
P
Site 7
T139
P
G
D
L
G
L
P
T
E
P
Q
D
T
P
G
Site 8
T144
L
P
T
E
P
Q
D
T
P
G
G
P
A
S
E
Site 9
S150
D
T
P
G
G
P
A
S
E
P
A
Q
P
P
G
Site 10
S160
A
Q
P
P
G
E
R
S
A
D
P
P
L
P
A
Site 11
T174
A
L
E
L
A
Q
A
T
E
R
P
S
A
D
A
Site 12
S178
A
Q
A
T
E
R
P
S
A
D
A
A
P
P
P
Site 13
S189
A
P
P
P
R
A
P
S
E
A
A
S
P
C
S
Site 14
S193
R
A
P
S
E
A
A
S
P
C
S
D
P
P
D
Site 15
S196
S
E
A
A
S
P
C
S
D
P
P
D
A
E
P
Site 16
T229
R
C
V
P
A
P
A
T
L
R
L
R
A
E
E
Site 17
S244
P
G
L
R
R
Q
L
S
E
E
P
S
P
R
S
Site 18
S248
R
Q
L
S
E
E
P
S
P
R
S
S
P
L
L
Site 19
S251
S
E
E
P
S
P
R
S
S
P
L
L
L
R
R
Site 20
S252
E
E
P
S
P
R
S
S
P
L
L
L
R
R
L
Site 21
S260
P
L
L
L
R
R
L
S
V
E
E
S
G
L
G
Site 22
S264
R
R
L
S
V
E
E
S
G
L
G
L
G
L
G
Site 23
S275
L
G
L
G
P
G
R
S
P
H
L
R
R
L
S
Site 24
S282
S
P
H
L
R
R
L
S
R
A
G
P
R
L
L
Site 25
S290
R
A
G
P
R
L
L
S
P
D
A
E
E
L
P
Site 26
S310
S
A
V
P
L
E
P
S
E
H
E
W
L
V
R
Site 27
T324
R
T
A
G
G
R
W
T
H
Q
L
H
G
L
L
Site 28
S356
A
L
H
W
A
A
K
S
G
D
G
E
M
A
L
Site 29
S382
P
V
D
V
N
A
R
S
H
G
G
Y
T
P
L
Site 30
Y386
N
A
R
S
H
G
G
Y
T
P
L
H
L
A
A
Site 31
T387
A
R
S
H
G
G
Y
T
P
L
H
L
A
A
L
Site 32
S418
Q
V
H
V
R
D
H
S
G
R
R
A
Y
Q
Y
Site 33
Y423
D
H
S
G
R
R
A
Y
Q
Y
L
R
P
G
S
Site 34
Y425
S
G
R
R
A
Y
Q
Y
L
R
P
G
S
S
Y
Site 35
S430
Y
Q
Y
L
R
P
G
S
S
Y
A
L
R
R
L
Site 36
Y432
Y
L
R
P
G
S
S
Y
A
L
R
R
L
L
G
Site 37
T446
G
D
P
G
L
R
G
T
T
E
P
D
A
T
G
Site 38
T447
D
P
G
L
R
G
T
T
E
P
D
A
T
G
G
Site 39
T452
G
T
T
E
P
D
A
T
G
G
G
S
G
S
L
Site 40
S458
A
T
G
G
G
S
G
S
L
A
A
R
R
P
V
Site 41
S499
L
A
R
G
L
K
K
S
S
S
F
S
K
F
L
Site 42
S500
A
R
G
L
K
K
S
S
S
F
S
K
F
L
S
Site 43
S501
R
G
L
K
K
S
S
S
F
S
K
F
L
S
A
Site 44
S503
L
K
K
S
S
S
F
S
K
F
L
S
A
S
P
Site 45
S507
S
S
F
S
K
F
L
S
A
S
P
M
A
P
R
Site 46
S509
F
S
K
F
L
S
A
S
P
M
A
P
R
K
K
Site 47
T517
P
M
A
P
R
K
K
T
K
I
R
G
G
L
P
Site 48
S530
L
P
A
F
S
E
I
S
R
R
P
T
P
G
P
Site 49
T534
S
E
I
S
R
R
P
T
P
G
P
L
A
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation