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Updated November 2019
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Protein Info
Short Name:
KIAA1033
Full Name:
WASH complex subunit 7
Alias:
K1033; LOC23325
Type:
Unknown function
Mass (Da):
136417
Number AA:
1173
UniProt ID:
Q2M389
International Prot ID:
IPI00298991
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
V
E
T
L
S
P
D
W
E
F
D
R
Site 2
S19
F
D
R
V
D
D
G
S
Q
K
I
H
A
E
V
Site 3
Y38
Y
G
K
F
L
E
E
Y
T
S
Q
L
R
R
I
Site 4
S40
K
F
L
E
E
Y
T
S
Q
L
R
R
I
E
D
Site 5
S52
I
E
D
A
L
D
D
S
I
G
D
V
W
D
F
Site 6
S74
K
L
L
P
Y
E
Q
S
S
L
L
E
L
I
K
Site 7
T82
S
L
L
E
L
I
K
T
E
N
K
V
L
N
K
Site 8
Y106
C
E
I
K
K
L
K
Y
E
A
E
T
K
F
Y
Site 9
Y113
Y
E
A
E
T
K
F
Y
N
G
L
L
F
Y
G
Site 10
Y119
F
Y
N
G
L
L
F
Y
G
E
G
A
T
D
A
Site 11
Y155
S
C
F
V
T
R
C
Y
E
V
V
M
N
V
V
Site 12
Y169
V
H
Q
L
A
A
L
Y
I
S
N
K
I
A
P
Site 13
T218
I
T
L
K
D
H
W
T
M
Y
K
R
L
L
K
Site 14
Y220
L
K
D
H
W
T
M
Y
K
R
L
L
K
S
V
Site 15
S226
M
Y
K
R
L
L
K
S
V
H
H
N
P
S
K
Site 16
S271
C
I
E
Q
Q
F
D
S
L
N
G
G
V
S
V
Site 17
S277
D
S
L
N
G
G
V
S
V
S
K
N
S
T
F
Site 18
S279
L
N
G
G
V
S
V
S
K
N
S
T
F
A
E
Site 19
T283
V
S
V
S
K
N
S
T
F
A
E
E
F
A
H
Site 20
Y315
E
I
D
Q
R
D
K
Y
V
G
I
C
G
L
F
Site 21
S339
I
D
K
K
F
Y
K
S
L
L
D
I
C
K
K
Site 22
S379
A
K
L
L
D
R
K
S
L
Q
A
I
K
I
H
Site 23
T389
A
I
K
I
H
R
D
T
F
L
Q
Q
K
A
Q
Site 24
S397
F
L
Q
Q
K
A
Q
S
L
T
K
D
V
Q
S
Site 25
T399
Q
Q
K
A
Q
S
L
T
K
D
V
Q
S
Y
Y
Site 26
S404
S
L
T
K
D
V
Q
S
Y
Y
V
F
V
S
S
Site 27
Y405
L
T
K
D
V
Q
S
Y
Y
V
F
V
S
S
W
Site 28
Y406
T
K
D
V
Q
S
Y
Y
V
F
V
S
S
W
M
Site 29
Y461
I
K
T
T
M
N
L
Y
M
S
M
Q
K
P
M
Site 30
T471
M
Q
K
P
M
T
K
T
S
V
K
A
L
C
R
Site 31
Y491
K
A
I
E
H
M
F
Y
R
R
S
M
V
V
A
Site 32
S494
E
H
M
F
Y
R
R
S
M
V
V
A
D
S
V
Site 33
S500
R
S
M
V
V
A
D
S
V
S
H
I
T
Q
H
Site 34
S517
H
Q
A
L
H
S
I
S
V
A
K
K
R
V
I
Site 35
S525
V
A
K
K
R
V
I
S
D
K
K
Y
S
E
Q
Site 36
Y529
R
V
I
S
D
K
K
Y
S
E
Q
R
L
D
V
Site 37
T552
N
T
L
N
G
P
S
T
K
Q
R
R
L
I
V
Site 38
T571
S
V
G
T
Q
M
K
T
F
K
D
E
E
L
F
Site 39
S591
M
K
K
L
D
L
I
S
E
L
R
E
R
V
Q
Site 40
Y616
H
R
A
V
F
P
I
Y
L
D
D
V
Y
E
N
Site 41
Y621
P
I
Y
L
D
D
V
Y
E
N
A
V
D
A
A
Site 42
Y632
V
D
A
A
R
L
H
Y
M
F
S
A
L
R
D
Site 43
Y653
H
A
R
H
L
E
S
Y
E
I
L
L
D
C
Y
Site 44
S687
I
E
K
D
L
R
L
S
V
H
T
H
L
K
L
Site 45
Y728
R
F
I
D
I
R
A
Y
V
T
H
Y
L
D
K
Site 46
Y732
I
R
A
Y
V
T
H
Y
L
D
K
T
F
Y
N
Site 47
T736
V
T
H
Y
L
D
K
T
F
Y
N
L
T
T
V
Site 48
T759
S
E
M
R
N
L
A
T
Q
R
Y
G
L
V
M
Site 49
T767
Q
R
Y
G
L
V
M
T
E
A
H
L
P
S
Q
Site 50
Y796
I
H
I
F
V
S
R
Y
L
Y
N
L
N
N
Q
Site 51
S826
N
I
R
H
I
A
N
S
I
R
T
H
G
T
G
Site 52
Y851
Q
F
L
K
K
K
F
Y
I
F
S
Q
F
M
Y
Site 53
Y858
Y
I
F
S
Q
F
M
Y
D
E
H
I
K
S
R
Site 54
Y884
K
D
Q
N
D
H
K
Y
P
F
D
R
A
E
K
Site 55
T902
G
I
R
K
L
G
I
T
P
E
G
Q
S
Y
L
Site 56
Y908
I
T
P
E
G
Q
S
Y
L
D
Q
F
R
Q
L
Site 57
S917
D
Q
F
R
Q
L
I
S
Q
I
G
N
A
M
G
Site 58
Y925
Q
I
G
N
A
M
G
Y
V
R
M
I
R
S
G
Site 59
S931
G
Y
V
R
M
I
R
S
G
G
L
H
C
S
S
Site 60
S937
R
S
G
G
L
H
C
S
S
N
A
I
R
F
V
Site 61
S975
K
A
A
R
H
L
D
S
V
L
S
D
H
T
R
Site 62
S978
R
H
L
D
S
V
L
S
D
H
T
R
N
S
A
Site 63
S984
L
S
D
H
T
R
N
S
A
E
G
T
E
Y
F
Site 64
T988
T
R
N
S
A
E
G
T
E
Y
F
K
M
L
V
Site 65
Y990
N
S
A
E
G
T
E
Y
F
K
M
L
V
D
V
Site 66
S1030
N
F
V
E
H
S
I
S
C
K
E
K
L
N
K
Site 67
Y1056
G
F
A
M
G
V
A
Y
I
L
K
L
L
D
Q
Site 68
Y1064
I
L
K
L
L
D
Q
Y
R
E
F
D
S
L
H
Site 69
S1075
D
S
L
H
W
F
Q
S
V
R
E
K
Y
L
K
Site 70
Y1080
F
Q
S
V
R
E
K
Y
L
K
E
I
R
A
V
Site 71
S1097
Q
Q
N
V
Q
S
A
S
Q
D
E
K
L
L
Q
Site 72
T1109
L
L
Q
T
M
N
L
T
Q
K
R
L
D
V
Y
Site 73
Y1116
T
Q
K
R
L
D
V
Y
L
Q
E
F
E
L
L
Site 74
T1139
I
F
F
R
A
D
K
T
A
A
E
E
N
Q
E
Site 75
T1156
E
K
E
E
E
T
K
T
S
N
G
D
L
S
D
Site 76
S1157
K
E
E
E
T
K
T
S
N
G
D
L
S
D
S
Site 77
S1162
K
T
S
N
G
D
L
S
D
S
T
V
S
A
D
Site 78
S1164
S
N
G
D
L
S
D
S
T
V
S
A
D
P
V
Site 79
T1165
N
G
D
L
S
D
S
T
V
S
A
D
P
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation