PhosphoNET

           
Protein Info 
   
Short Name:  K24
Full Name:  Keratin, type I cytoskeletal 24
Alias:  Cytokeratin-24; FLJ20261; K1C24; Keratin 24; Keratin-24; KRT24; MGC138169; MGC138173; Type I keratin-24
Type:  Cytoskeletal protein
Mass (Da):  55069
Number AA:  525
UniProt ID:  Q2M2I5
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005882     Uniprot OncoNet
Molecular Function:  GO:0005198     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MSCSSRASSSRA
Site 2S8MSCSSRASSSRAGGS
Site 3S9SCSSRASSSRAGGSS
Site 4S10CSSRASSSRAGGSSS
Site 5S15SSSRAGGSSSARVSA
Site 6S16SSRAGGSSSARVSAG
Site 7S17SRAGGSSSARVSAGG
Site 8S21GSSSARVSAGGSSFS
Site 9S25ARVSAGGSSFSSGSR
Site 10S26RVSAGGSSFSSGSRC
Site 11S28SAGGSSFSSGSRCGL
Site 12S29AGGSSFSSGSRCGLG
Site 13S31GSSFSSGSRCGLGGS
Site 14S38SRCGLGGSSAQGFRG
Site 15S39RCGLGGSSAQGFRGG
Site 16S48QGFRGGASSCSLSGG
Site 17S49GFRGGASSCSLSGGS
Site 18S51RGGASSCSLSGGSSG
Site 19S56SCSLSGGSSGAFGGS
Site 20S81GGGFGGASGSGTGFG
Site 21S83GFGGASGSGTGFGGG
Site 22T85GGASGSGTGFGGGSS
Site 23S97GSSFGGVSGFGRGSG
Site 24S103VSGFGRGSGFCGSSR
Site 25S108RGSGFCGSSRFSSGA
Site 26S109GSGFCGSSRFSSGAT
Site 27S112FCGSSRFSSGATGGF
Site 28S113CGSSRFSSGATGGFY
Site 29T116SRFSSGATGGFYSYG
Site 30Y120SGATGGFYSYGGGMG
Site 31S121GATGGFYSYGGGMGG
Site 32Y122ATGGFYSYGGGMGGG
Site 33S137VGDGGLFSGGEKQTM
Site 34Y154LNDRLANYLDKVRAL
Site 35T166RALEEANTDLENKIK
Site 36Y176ENKIKEWYDKYGPGS
Site 37Y179IKEWYDKYGPGSGDG
Site 38S183YDKYGPGSGDGGSGR
Site 39S188PGSGDGGSGRDYSKY
Site 40Y192DGGSGRDYSKYYSII
Site 41S193GGSGRDYSKYYSIIE
Site 42Y195SGRDYSKYYSIIEDL
Site 43Y196GRDYSKYYSIIEDLR
Site 44S197RDYSKYYSIIEDLRN
Site 45Y234ADDFRLKYENELCLR
Site 46S243NELCLRQSVEADING
Site 47T259RKVLDDLTMTRSDLE
Site 48S263DDLTMTRSDLEMQIE
Site 49S271DLEMQIESFTEELAY
Site 50Y278SFTEELAYLRKNHEE
Site 51T299GSSGGEVTVEMNAAP
Site 52T311AAPGTDLTKLLNDMR
Site 53Y321LNDMRAQYEELAEQN
Site 54S340EERFNKQSASLQAQI
Site 55S342RFNKQSASLQAQIST
Site 56T367EITELKRTLQALEIE
Site 57S383QSQLAMKSSLEGTLA
Site 58S384SQLAMKSSLEGTLAD
Site 59T388MKSSLEGTLADTEAG
Site 60T392LEGTLADTEAGYVAQ
Site 61T405AQLSEIQTQISALEE
Site 62S408SEIQTQISALEEEIC
Site 63T436KQLLDIKTRLEVEIE
Site 64T444RLEVEIETYRRLLDG
Site 65Y445LEVEIETYRRLLDGE
Site 66S456LDGEGGGSSFAEFGG
Site 67S457DGEGGGSSFAEFGGR
Site 68S466AEFGGRNSGSVNMGS
Site 69S468FGGRNSGSVNMGSRD
Site 70S473SGSVNMGSRDLVSGD
Site 71S478MGSRDLVSGDSRSGS
Site 72S481RDLVSGDSRSGSCSG
Site 73S483LVSGDSRSGSCSGQG
Site 74S485SGDSRSGSCSGQGRD
Site 75S487DSRSGSCSGQGRDSS
Site 76S493CSGQGRDSSKTRVTK
Site 77S494SGQGRDSSKTRVTKT
Site 78T496QGRDSSKTRVTKTIV
Site 79T499DSSKTRVTKTIVEEL
Site 80T501SKTRVTKTIVEELVD
Site 81S514VDGKVVSSQVSSISE
Site 82S520SSQVSSISEVKVK__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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