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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC27
Full Name:
Coiled-coil domain-containing protein 27
Alias:
Type:
Mass (Da):
75354
Number AA:
656
UniProt ID:
Q2M243
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
F
E
A
I
F
P
S
T
P
Q
A
R
L
K
R
Site 2
S25
P
R
E
K
P
G
L
S
S
F
R
S
T
F
R
Site 3
S26
R
E
K
P
G
L
S
S
F
R
S
T
F
R
Q
Site 4
S29
P
G
L
S
S
F
R
S
T
F
R
Q
Q
S
S
Site 5
T30
G
L
S
S
F
R
S
T
F
R
Q
Q
S
S
L
Site 6
S35
R
S
T
F
R
Q
Q
S
S
L
G
L
C
I
P
Site 7
S36
S
T
F
R
Q
Q
S
S
L
G
L
C
I
P
R
Site 8
S51
L
M
L
P
K
E
A
S
P
S
Q
R
H
S
S
Site 9
S53
L
P
K
E
A
S
P
S
Q
R
H
S
S
M
S
Site 10
S57
A
S
P
S
Q
R
H
S
S
M
S
S
S
M
A
Site 11
S58
S
P
S
Q
R
H
S
S
M
S
S
S
M
A
R
Site 12
S60
S
Q
R
H
S
S
M
S
S
S
M
A
R
A
L
Site 13
S61
Q
R
H
S
S
M
S
S
S
M
A
R
A
L
V
Site 14
S62
R
H
S
S
M
S
S
S
M
A
R
A
L
V
L
Site 15
S72
R
A
L
V
L
L
Q
S
M
A
S
R
D
A
R
Site 16
T91
K
P
H
Q
K
P
R
T
L
S
K
S
V
Q
T
Site 17
S93
H
Q
K
P
R
T
L
S
K
S
V
Q
T
I
S
Site 18
S95
K
P
R
T
L
S
K
S
V
Q
T
I
S
R
Y
Site 19
S100
S
K
S
V
Q
T
I
S
R
Y
Y
R
K
T
S
Site 20
Y102
S
V
Q
T
I
S
R
Y
Y
R
K
T
S
E
P
Site 21
Y103
V
Q
T
I
S
R
Y
Y
R
K
T
S
E
P
K
Site 22
T106
I
S
R
Y
Y
R
K
T
S
E
P
K
D
A
A
Site 23
S107
S
R
Y
Y
R
K
T
S
E
P
K
D
A
A
S
Site 24
S114
S
E
P
K
D
A
A
S
L
T
G
F
M
S
K
Site 25
T116
P
K
D
A
A
S
L
T
G
F
M
S
K
M
E
Site 26
S120
A
S
L
T
G
F
M
S
K
M
E
L
R
R
V
Site 27
T130
E
L
R
R
V
F
P
T
H
P
D
C
P
Q
F
Site 28
S138
H
P
D
C
P
Q
F
S
T
R
A
T
S
M
S
Site 29
T139
P
D
C
P
Q
F
S
T
R
A
T
S
M
S
H
Site 30
T142
P
Q
F
S
T
R
A
T
S
M
S
H
C
G
S
Site 31
S143
Q
F
S
T
R
A
T
S
M
S
H
C
G
S
P
Site 32
S145
S
T
R
A
T
S
M
S
H
C
G
S
P
T
E
Site 33
S149
T
S
M
S
H
C
G
S
P
T
E
A
D
L
S
Site 34
S156
S
P
T
E
A
D
L
S
G
E
I
D
N
S
S
Site 35
S162
L
S
G
E
I
D
N
S
S
E
T
W
R
G
T
Site 36
S163
S
G
E
I
D
N
S
S
E
T
W
R
G
T
Q
Site 37
T165
E
I
D
N
S
S
E
T
W
R
G
T
Q
D
L
Site 38
T169
S
S
E
T
W
R
G
T
Q
D
L
F
L
A
R
Site 39
S179
L
F
L
A
R
R
G
S
D
T
N
V
D
G
Y
Site 40
T181
L
A
R
R
G
S
D
T
N
V
D
G
Y
L
L
Site 41
Y186
S
D
T
N
V
D
G
Y
L
L
P
F
S
K
S
Site 42
S191
D
G
Y
L
L
P
F
S
K
S
I
C
E
F
D
Site 43
Y199
K
S
I
C
E
F
D
Y
L
R
K
R
R
K
S
Site 44
S206
Y
L
R
K
R
R
K
S
Q
T
L
S
P
V
T
Site 45
T208
R
K
R
R
K
S
Q
T
L
S
P
V
T
S
S
Site 46
S210
R
R
K
S
Q
T
L
S
P
V
T
S
S
S
V
Site 47
T213
S
Q
T
L
S
P
V
T
S
S
S
V
A
S
Q
Site 48
S214
Q
T
L
S
P
V
T
S
S
S
V
A
S
Q
S
Site 49
S215
T
L
S
P
V
T
S
S
S
V
A
S
Q
S
C
Site 50
S219
V
T
S
S
S
V
A
S
Q
S
C
L
R
K
R
Site 51
S221
S
S
S
V
A
S
Q
S
C
L
R
K
R
M
P
Site 52
Y230
L
R
K
R
M
P
W
Y
L
S
V
I
H
E
K
Site 53
S281
K
G
K
G
Q
E
T
S
M
S
P
G
R
R
E
Site 54
S283
K
G
Q
E
T
S
M
S
P
G
R
R
E
Q
L
Site 55
S291
P
G
R
R
E
Q
L
S
D
A
S
L
K
L
G
Site 56
S294
R
E
Q
L
S
D
A
S
L
K
L
G
R
L
S
Site 57
S307
L
S
L
L
K
A
F
S
R
H
E
E
E
L
Q
Site 58
T353
E
P
D
G
V
E
D
T
G
A
W
G
G
V
S
Site 59
S360
T
G
A
W
G
G
V
S
Q
M
G
S
V
H
E
Site 60
S364
G
G
V
S
Q
M
G
S
V
H
E
E
G
S
E
Site 61
S384
E
G
D
R
D
E
D
S
E
E
R
E
L
P
E
Site 62
S401
E
I
P
R
R
R
A
S
S
L
A
E
S
F
E
Site 63
S402
I
P
R
R
R
A
S
S
L
A
E
S
F
E
E
Site 64
S406
R
A
S
S
L
A
E
S
F
E
E
E
L
L
A
Site 65
T434
F
N
L
E
A
T
R
T
R
Y
S
L
A
T
G
Site 66
S437
E
A
T
R
T
R
Y
S
L
A
T
G
V
I
A
Site 67
S486
Q
A
M
T
D
K
F
S
N
L
R
E
D
K
K
Site 68
T520
S
E
L
E
R
K
L
T
K
R
D
C
V
I
S
Site 69
S527
T
K
R
D
C
V
I
S
E
L
D
T
K
V
S
Site 70
T531
C
V
I
S
E
L
D
T
K
V
S
Q
L
Q
E
Site 71
S534
S
E
L
D
T
K
V
S
Q
L
Q
E
Q
V
E
Site 72
S559
Q
L
Q
E
D
L
Q
S
K
K
E
M
I
Q
Q
Site 73
S577
H
T
R
V
A
L
E
S
S
Q
S
R
L
E
R
Site 74
S578
T
R
V
A
L
E
S
S
Q
S
R
L
E
R
L
Site 75
S580
V
A
L
E
S
S
Q
S
R
L
E
R
L
R
N
Site 76
T593
R
N
K
I
I
Q
A
T
F
S
I
S
G
T
K
Site 77
S601
F
S
I
S
G
T
K
S
L
A
N
E
I
S
D
Site 78
S607
K
S
L
A
N
E
I
S
D
N
D
I
L
E
A
Site 79
S620
E
A
L
Q
R
I
I
S
E
R
S
D
Y
Y
N
Site 80
Y625
I
I
S
E
R
S
D
Y
Y
N
Q
L
K
Q
K
Site 81
Y626
I
S
E
R
S
D
Y
Y
N
Q
L
K
Q
K
G
Site 82
S642
K
V
P
P
L
Q
Q
S
E
A
F
L
T
S
K
Site 83
T647
Q
Q
S
E
A
F
L
T
S
K
S
K
K
G
T
Site 84
S648
Q
S
E
A
F
L
T
S
K
S
K
K
G
T
S
Site 85
S650
E
A
F
L
T
S
K
S
K
K
G
T
S
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation