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Updated November 2019
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Protein Info
Short Name:
KIAA0753
Full Name:
Uncharacterized protein KIAA0753
Alias:
Type:
Mass (Da):
109407
Number AA:
967
UniProt ID:
Q2KHM9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
R
T
Q
L
D
G
R
S
D
P
K
V
L
Q
T
Site 2
S44
N
R
N
V
P
T
H
S
S
N
L
A
I
R
Y
Site 3
Y51
S
S
N
L
A
I
R
Y
S
C
P
H
A
I
R
Site 4
S88
P
D
L
G
S
S
V
S
F
S
V
I
S
Q
E
Site 5
S90
L
G
S
S
V
S
F
S
V
I
S
Q
E
R
L
Site 6
S93
S
V
S
F
S
V
I
S
Q
E
R
L
S
Y
A
Site 7
S98
V
I
S
Q
E
R
L
S
Y
A
V
H
L
A
R
Site 8
Y99
I
S
Q
E
R
L
S
Y
A
V
H
L
A
R
R
Site 9
S124
I
K
E
H
H
L
R
S
Q
P
Q
S
S
Q
K
Site 10
S128
H
L
R
S
Q
P
Q
S
S
Q
K
C
G
H
T
Site 11
S129
L
R
S
Q
P
Q
S
S
Q
K
C
G
H
T
K
Site 12
Y137
Q
K
C
G
H
T
K
Y
K
I
P
D
H
R
V
Site 13
S149
H
R
V
E
R
K
E
S
K
S
Q
A
A
C
Q
Site 14
S151
V
E
R
K
E
S
K
S
Q
A
A
C
Q
C
S
Site 15
S158
S
Q
A
A
C
Q
C
S
H
Q
P
S
K
V
E
Site 16
S162
C
Q
C
S
H
Q
P
S
K
V
E
I
S
S
S
Site 17
S169
S
K
V
E
I
S
S
S
G
A
K
V
Y
L
Y
Site 18
Y174
S
S
S
G
A
K
V
Y
L
Y
S
S
H
P
G
Site 19
Y176
S
G
A
K
V
Y
L
Y
S
S
H
P
G
Q
S
Site 20
S177
G
A
K
V
Y
L
Y
S
S
H
P
G
Q
S
D
Site 21
S178
A
K
V
Y
L
Y
S
S
H
P
G
Q
S
D
L
Site 22
S183
Y
S
S
H
P
G
Q
S
D
L
T
V
P
N
S
Site 23
T186
H
P
G
Q
S
D
L
T
V
P
N
S
P
P
T
Site 24
S190
S
D
L
T
V
P
N
S
P
P
T
H
D
P
G
Site 25
T193
T
V
P
N
S
P
P
T
H
D
P
G
L
Q
P
Site 26
S211
I
G
D
H
K
N
I
S
E
Q
K
S
L
L
E
Site 27
S215
K
N
I
S
E
Q
K
S
L
L
E
V
Q
R
L
Site 28
S227
Q
R
L
Q
K
E
L
S
S
C
I
H
K
I
E
Site 29
S265
R
Q
E
Q
A
A
R
S
A
R
M
L
Y
V
L
Site 30
Y270
A
R
S
A
R
M
L
Y
V
L
Q
Q
Q
V
K
Site 31
S287
Q
E
E
L
D
K
L
S
P
H
K
I
K
H
T
Site 32
S297
K
I
K
H
T
K
K
S
W
A
M
S
K
L
A
Site 33
S301
T
K
K
S
W
A
M
S
K
L
A
A
A
H
R
Site 34
T322
Q
M
F
V
T
Q
F
T
D
R
G
E
H
P
L
Site 35
S338
A
R
C
K
E
L
G
S
L
I
R
Q
L
S
L
Site 36
S372
Q
Q
I
E
A
L
E
S
L
L
E
K
K
L
S
Site 37
S379
S
L
L
E
K
K
L
S
P
K
K
V
K
K
C
Site 38
S388
K
K
V
K
K
C
F
S
E
I
R
S
R
F
P
Site 39
S392
K
C
F
S
E
I
R
S
R
F
P
I
G
S
Q
Site 40
S398
R
S
R
F
P
I
G
S
Q
K
A
L
E
R
W
Site 41
S407
K
A
L
E
R
W
P
S
T
S
P
K
G
E
R
Site 42
S409
L
E
R
W
P
S
T
S
P
K
G
E
R
R
P
Site 43
T418
K
G
E
R
R
P
L
T
A
K
D
T
F
P
Q
Site 44
T422
R
P
L
T
A
K
D
T
F
P
Q
E
T
S
R
Site 45
T427
K
D
T
F
P
Q
E
T
S
R
P
S
V
A
K
Site 46
S431
P
Q
E
T
S
R
P
S
V
A
K
Q
L
L
A
Site 47
Y441
K
Q
L
L
A
D
K
Y
Q
P
N
T
E
L
P
Site 48
T445
A
D
K
Y
Q
P
N
T
E
L
P
E
T
Q
R
Site 49
T450
P
N
T
E
L
P
E
T
Q
R
L
Q
S
E
L
Site 50
S455
P
E
T
Q
R
L
Q
S
E
L
D
V
L
D
A
Site 51
S476
G
P
F
I
L
D
Q
S
A
S
F
K
D
E
V
Site 52
T498
A
G
K
K
K
P
V
T
E
N
V
P
F
R
K
Site 53
T508
V
P
F
R
K
K
D
T
L
A
P
A
R
Q
Q
Site 54
S526
K
A
E
R
G
R
Q
S
Q
P
H
S
K
S
R
Site 55
S530
G
R
Q
S
Q
P
H
S
K
S
R
V
Q
Q
T
Site 56
S532
Q
S
Q
P
H
S
K
S
R
V
Q
Q
T
T
V
Site 57
T538
K
S
R
V
Q
Q
T
T
V
S
S
R
L
K
M
Site 58
S540
R
V
Q
Q
T
T
V
S
S
R
L
K
M
N
R
Site 59
T563
P
W
I
P
P
N
P
T
S
P
P
A
S
P
K
Site 60
S564
W
I
P
P
N
P
T
S
P
P
A
S
P
K
C
Site 61
S568
N
P
T
S
P
P
A
S
P
K
C
A
A
W
L
Site 62
S580
A
W
L
K
V
K
T
S
P
R
D
A
T
K
E
Site 63
T585
K
T
S
P
R
D
A
T
K
E
P
L
Q
Q
E
Site 64
T601
P
Q
E
E
S
H
L
T
G
A
V
E
H
E
A
Site 65
S619
A
W
L
D
A
E
T
S
K
R
L
K
E
L
E
Site 66
S635
L
K
A
K
E
I
D
S
M
Q
K
Q
R
L
D
Site 67
T648
L
D
W
L
D
A
E
T
S
R
R
T
K
E
L
Site 68
S649
D
W
L
D
A
E
T
S
R
R
T
K
E
L
N
Site 69
T652
D
A
E
T
S
R
R
T
K
E
L
N
E
L
K
Site 70
T674
Q
Q
L
S
V
S
A
T
H
L
A
D
K
V
E
Site 71
S700
V
K
A
Q
R
V
N
S
T
T
E
A
N
I
H
Site 72
T701
K
A
Q
R
V
N
S
T
T
E
A
N
I
H
L
Site 73
T702
A
Q
R
V
N
S
T
T
E
A
N
I
H
L
K
Site 74
S713
I
H
L
K
D
G
S
S
V
N
T
A
K
A
Q
Site 75
T716
K
D
G
S
S
V
N
T
A
K
A
Q
P
A
Q
Site 76
T765
L
G
S
E
T
L
A
T
V
E
D
S
K
D
S
Site 77
S772
T
V
E
D
S
K
D
S
P
D
L
E
I
M
M
Site 78
Y788
R
M
E
E
M
E
K
Y
Q
E
S
V
R
Q
R
Site 79
S791
E
M
E
K
Y
Q
E
S
V
R
Q
R
Y
N
K
Site 80
Y796
Q
E
S
V
R
Q
R
Y
N
K
I
A
Y
A
D
Site 81
Y801
Q
R
Y
N
K
I
A
Y
A
D
P
R
L
W
M
Site 82
S826
A
I
S
E
K
P
L
S
P
H
P
I
R
I
T
Site 83
T833
S
P
H
P
I
R
I
T
K
T
V
D
R
K
D
Site 84
T835
H
P
I
R
I
T
K
T
V
D
R
K
D
P
A
Site 85
S855
E
R
P
C
N
G
N
S
L
D
E
S
V
G
T
Site 86
S859
N
G
N
S
L
D
E
S
V
G
T
E
E
G
S
Site 87
T862
S
L
D
E
S
V
G
T
E
E
G
S
E
K
R
Site 88
S866
S
V
G
T
E
E
G
S
E
K
R
E
A
P
L
Site 89
S875
K
R
E
A
P
L
L
S
L
A
E
D
S
Q
Q
Site 90
S880
L
L
S
L
A
E
D
S
Q
Q
K
E
G
R
A
Site 91
S898
V
P
P
G
M
R
H
S
I
G
D
Y
C
S
R
Site 92
Y902
M
R
H
S
I
G
D
Y
C
S
R
F
E
Q
Y
Site 93
Y909
Y
C
S
R
F
E
Q
Y
L
R
I
I
S
H
E
Site 94
S914
E
Q
Y
L
R
I
I
S
H
E
A
V
G
S
F
Site 95
S929
N
P
W
L
I
A
E
S
F
S
E
E
L
V
D
Site 96
Y953
L
Q
D
M
C
E
D
Y
A
E
A
V
F
T
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation