PhosphoNET

           
Protein Info 
   
Short Name:  DOK7
Full Name:  Protein Dok-7
Alias:  Downstream of tyrosine kinase 7
Type: 
Mass (Da):  53097
Number AA:  504
UniProt ID:  Q18PE1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S21RDGKKWKSRWLVLRK
Site 2Y41DCLLMLVYKDKSERI
Site 3S45MLVYKDKSERIKGLR
Site 4S55IKGLRERSSLTLEDI
Site 5S56KGLRERSSLTLEDIC
Site 6T58LRERSSLTLEDICGL
Site 7Y106AWDARIRYALGEVHR
Site 8T117EVHRFHVTVAPGTKL
Site 9S126APGTKLESGPATLHL
Site 10T130KLESGPATLHLCNDV
Site 11S155VTGQWKLSDLRRYGA
Site 12Y160KLSDLRRYGAVPSGF
Site 13S165RRYGAVPSGFIFEGG
Site 14S204DCIVRGISPTKGPFG
Site 15T206IVRGISPTKGPFGLR
Site 16S220RPVLPDPSPPGPSTV
Site 17T226PSPPGPSTVEERVAQ
Site 18T238VAQEALETLQLEKRL
Site 19S246LQLEKRLSLLSHAGR
Site 20S249EKRLSLLSHAGRPGS
Site 21S256SHAGRPGSGGDDRSL
Site 22S262GSGGDDRSLSSSSSE
Site 23S264GGDDRSLSSSSSEAS
Site 24S265GDDRSLSSSSSEASH
Site 25S266DDRSLSSSSSEASHL
Site 26S267DRSLSSSSSEASHLD
Site 27S268RSLSSSSSEASHLDV
Site 28S271SSSSSEASHLDVSAS
Site 29S276EASHLDVSASSRLTA
Site 30S278SHLDVSASSRLTAWP
Site 31T282VSASSRLTAWPEQSS
Site 32S288LTAWPEQSSSSASTS
Site 33S289TAWPEQSSSSASTSQ
Site 34S290AWPEQSSSSASTSQE
Site 35S291WPEQSSSSASTSQEG
Site 36S293EQSSSSASTSQEGPR
Site 37T294QSSSSASTSQEGPRP
Site 38S295SSSSASTSQEGPRPA
Site 39S334LQEVGRQSSSDSGIA
Site 40S335QEVGRQSSSDSGIAT
Site 41S336EVGRQSSSDSGIATG
Site 42S338GRQSSSDSGIATGSH
Site 43T342SSDSGIATGSHSSYS
Site 44S344DSGIATGSHSSYSSS
Site 45S346GIATGSHSSYSSSLS
Site 46S347IATGSHSSYSSSLSS
Site 47Y348ATGSHSSYSSSLSSY
Site 48S349TGSHSSYSSSLSSYA
Site 49S350GSHSSYSSSLSSYAG
Site 50S351SHSSYSSSLSSYAGS
Site 51S353SSYSSSLSSYAGSSL
Site 52S354SYSSSLSSYAGSSLD
Site 53Y355YSSSLSSYAGSSLDV
Site 54S358SLSSYAGSSLDVWRA
Site 55S359LSSYAGSSLDVWRAT
Site 56Y395CLPGTVEYQVPTSLR
Site 57S400VEYQVPTSLRAHYDT
Site 58Y405PTSLRAHYDTPRSLC
Site 59T407SLRAHYDTPRSLCLA
Site 60S410AHYDTPRSLCLAPRD
Site 61S419CLAPRDHSPPSQGSP
Site 62S422PRDHSPPSQGSPGNS
Site 63S425HSPPSQGSPGNSAAR
Site 64S429SQGSPGNSAARDSGG
Site 65S434GNSAARDSGGQTSAG
Site 66T438ARDSGGQTSAGCPSG
Site 67S439RDSGGQTSAGCPSGW
Site 68T449CPSGWLGTRRRGLVM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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