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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IMPG1
Full Name:
Interphotoreceptor matrix proteoglycan 1
Alias:
GP147; Interphotoreceptor matrix proteoglycan 1; IPM150; IPM-150; SPACR
Type:
Mass (Da):
89390
Number AA:
UniProt ID:
Q17R60
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005201
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
K
D
I
S
I
N
I
Y
H
S
E
T
K
D
I
Site 2
T44
D
N
P
P
R
N
E
T
T
E
S
T
E
K
M
Site 3
S47
P
R
N
E
T
T
E
S
T
E
K
M
Y
K
M
Site 4
T56
E
K
M
Y
K
M
S
T
M
R
R
I
F
D
L
Site 5
T68
F
D
L
A
K
H
R
T
K
R
S
A
F
F
P
Site 6
S92
S
M
K
Q
I
L
D
S
L
Q
A
Y
Y
R
L
Site 7
T120
F
L
D
R
I
P
D
T
G
E
Y
Q
D
W
V
Site 8
Y123
R
I
P
D
T
G
E
Y
Q
D
W
V
S
I
C
Site 9
S145
F
D
I
G
K
N
F
S
N
S
Q
E
H
L
D
Site 10
S147
I
G
K
N
F
S
N
S
Q
E
H
L
D
L
L
Site 11
S162
Q
Q
R
I
K
Q
R
S
F
P
D
R
K
D
E
Site 12
S171
P
D
R
K
D
E
I
S
A
E
K
T
L
G
E
Site 13
T175
D
E
I
S
A
E
K
T
L
G
E
P
G
E
T
Site 14
T200
S
L
G
P
F
P
L
T
P
D
D
T
L
L
N
Site 15
T204
F
P
L
T
P
D
D
T
L
L
N
E
I
L
D
Site 16
T213
L
N
E
I
L
D
N
T
L
N
D
T
K
M
P
Site 17
T217
L
D
N
T
L
N
D
T
K
M
P
T
T
E
R
Site 18
T222
N
D
T
K
M
P
T
T
E
R
E
T
E
F
A
Site 19
T226
M
P
T
T
E
R
E
T
E
F
A
V
L
E
E
Site 20
S239
E
E
Q
R
V
E
L
S
V
S
L
V
N
Q
K
Site 21
S241
Q
R
V
E
L
S
V
S
L
V
N
Q
K
F
K
Site 22
S254
F
K
A
E
L
A
D
S
Q
S
P
Y
Y
Q
E
Site 23
S256
A
E
L
A
D
S
Q
S
P
Y
Y
Q
E
L
A
Site 24
Y258
L
A
D
S
Q
S
P
Y
Y
Q
E
L
A
G
K
Site 25
Y259
A
D
S
Q
S
P
Y
Y
Q
E
L
A
G
K
S
Site 26
S297
P
K
K
E
K
D
G
S
S
S
T
E
M
Q
L
Site 27
S299
K
E
K
D
G
S
S
S
T
E
M
Q
L
T
A
Site 28
T305
S
S
T
E
M
Q
L
T
A
I
F
K
R
H
S
Site 29
S312
T
A
I
F
K
R
H
S
A
E
A
K
S
P
A
Site 30
S317
R
H
S
A
E
A
K
S
P
A
S
D
L
L
S
Site 31
S320
A
E
A
K
S
P
A
S
D
L
L
S
F
D
S
Site 32
S324
S
P
A
S
D
L
L
S
F
D
S
N
K
I
E
Site 33
S327
S
D
L
L
S
F
D
S
N
K
I
E
S
E
E
Site 34
Y336
K
I
E
S
E
E
V
Y
H
G
T
M
E
E
D
Site 35
Y349
E
D
K
Q
P
E
I
Y
L
T
A
T
D
L
K
Site 36
T351
K
Q
P
E
I
Y
L
T
A
T
D
L
K
R
L
Site 37
S360
T
D
L
K
R
L
I
S
K
A
L
E
E
E
Q
Site 38
S368
K
A
L
E
E
E
Q
S
L
D
V
G
T
I
Q
Site 39
T391
L
P
A
F
G
P
D
T
Q
S
E
L
P
T
S
Site 40
S393
A
F
G
P
D
T
Q
S
E
L
P
T
S
F
A
Site 41
S398
T
Q
S
E
L
P
T
S
F
A
V
I
T
E
D
Site 42
S409
I
T
E
D
A
T
L
S
P
E
L
P
P
V
E
Site 43
T421
P
V
E
P
Q
L
E
T
V
D
G
A
E
H
G
Site 44
T432
A
E
H
G
L
P
D
T
S
W
S
P
P
A
M
Site 45
S433
E
H
G
L
P
D
T
S
W
S
P
P
A
M
A
Site 46
S435
G
L
P
D
T
S
W
S
P
P
A
M
A
S
T
Site 47
S441
W
S
P
P
A
M
A
S
T
S
L
S
E
A
P
Site 48
S443
P
P
A
M
A
S
T
S
L
S
E
A
P
P
F
Site 49
T460
A
S
S
I
F
S
L
T
D
Q
G
T
T
D
T
Site 50
S484
P
G
L
T
I
P
T
S
D
Y
S
A
I
S
Q
Site 51
S497
S
Q
L
A
L
G
I
S
H
P
P
A
S
S
D
Site 52
S502
G
I
S
H
P
P
A
S
S
D
D
S
R
S
S
Site 53
S503
I
S
H
P
P
A
S
S
D
D
S
R
S
S
A
Site 54
S506
P
P
A
S
S
D
D
S
R
S
S
A
G
G
E
Site 55
S508
A
S
S
D
D
S
R
S
S
A
G
G
E
D
M
Site 56
S509
S
S
D
D
S
R
S
S
A
G
G
E
D
M
V
Site 57
S525
H
L
D
E
M
D
L
S
D
T
P
A
P
S
E
Site 58
T527
D
E
M
D
L
S
D
T
P
A
P
S
E
V
P
Site 59
S531
L
S
D
T
P
A
P
S
E
V
P
E
L
S
E
Site 60
S537
P
S
E
V
P
E
L
S
E
Y
V
S
V
P
D
Site 61
Y539
E
V
P
E
L
S
E
Y
V
S
V
P
D
H
F
Site 62
S541
P
E
L
S
E
Y
V
S
V
P
D
H
F
L
E
Site 63
T550
P
D
H
F
L
E
D
T
T
P
V
S
A
L
Q
Site 64
T551
D
H
F
L
E
D
T
T
P
V
S
A
L
Q
Y
Site 65
S554
L
E
D
T
T
P
V
S
A
L
Q
Y
I
T
T
Site 66
S563
L
Q
Y
I
T
T
S
S
M
T
I
A
P
K
G
Site 67
S587
R
V
A
N
M
A
F
S
N
D
L
F
N
K
S
Site 68
S595
N
D
L
F
N
K
S
S
L
E
Y
R
A
L
E
Site 69
S637
N
G
S
V
I
V
N
S
K
M
K
F
A
K
S
Site 70
S644
S
K
M
K
F
A
K
S
V
P
Y
N
L
T
K
Site 71
S662
G
V
L
E
D
F
R
S
A
A
A
Q
Q
L
H
Site 72
S674
Q
L
H
L
E
I
D
S
Y
S
L
N
I
E
P
Site 73
Y675
L
H
L
E
I
D
S
Y
S
L
N
I
E
P
A
Site 74
S676
H
L
E
I
D
S
Y
S
L
N
I
E
P
A
D
Site 75
Y716
E
C
R
C
K
P
G
Y
D
S
Q
G
S
L
D
Site 76
S718
R
C
K
P
G
Y
D
S
Q
G
S
L
D
G
L
Site 77
S721
P
G
Y
D
S
Q
G
S
L
D
G
L
E
P
G
Site 78
T734
P
G
L
C
G
P
G
T
K
E
C
E
V
L
Q
Site 79
S753
P
C
R
L
P
D
H
S
E
N
Q
A
Y
K
T
Site 80
Y758
D
H
S
E
N
Q
A
Y
K
T
S
V
K
K
F
Site 81
S775
Q
Q
N
N
K
V
I
S
K
R
N
S
E
L
L
Site 82
S779
K
V
I
S
K
R
N
S
E
L
L
T
V
E
Y
Site 83
T783
K
R
N
S
E
L
L
T
V
E
Y
E
E
F
N
Site 84
Y786
S
E
L
L
T
V
E
Y
E
E
F
N
H
Q
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation