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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IMMT
Full Name:
Mitochondrial inner membrane protein
Alias:
HMP; Inner membrane protein, mitochondrial; Mitofilin; P87; P87/89; P89; Proliferation-inducing gene 4 protein
Type:
Mitochondrial; Membrane protein, integral
Mass (Da):
83678
Number AA:
758
UniProt ID:
Q16891
International Prot ID:
IPI00009960
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031305
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
P
L
R
P
C
R
R
Y
S
T
S
G
S
S
G
Site 2
S34
L
R
P
C
R
R
Y
S
T
S
G
S
S
G
L
Site 3
T35
R
P
C
R
R
Y
S
T
S
G
S
S
G
L
T
Site 4
S36
P
C
R
R
Y
S
T
S
G
S
S
G
L
T
T
Site 5
S38
R
R
Y
S
T
S
G
S
S
G
L
T
T
G
K
Site 6
T42
T
S
G
S
S
G
L
T
T
G
K
I
A
G
A
Site 7
T43
S
G
S
S
G
L
T
T
G
K
I
A
G
A
G
Site 8
S69
I
L
Y
A
K
W
D
S
H
F
R
E
S
V
E
Site 9
S74
W
D
S
H
F
R
E
S
V
E
K
T
I
P
Y
Site 10
T78
F
R
E
S
V
E
K
T
I
P
Y
S
D
K
L
Site 11
S82
V
E
K
T
I
P
Y
S
D
K
L
F
E
M
V
Site 12
Y95
M
V
L
G
P
A
A
Y
N
V
P
L
P
K
K
Site 13
S103
N
V
P
L
P
K
K
S
I
Q
S
G
P
L
K
Site 14
S106
L
P
K
K
S
I
Q
S
G
P
L
K
I
S
S
Site 15
S113
S
G
P
L
K
I
S
S
V
S
E
V
M
K
E
Site 16
S115
P
L
K
I
S
S
V
S
E
V
M
K
E
S
K
Site 17
S126
K
E
S
K
Q
P
A
S
Q
L
Q
K
Q
K
G
Site 18
T135
L
Q
K
Q
K
G
D
T
P
A
S
A
T
A
P
Site 19
S138
Q
K
G
D
T
P
A
S
A
T
A
P
T
E
A
Site 20
T140
G
D
T
P
A
S
A
T
A
P
T
E
A
A
Q
Site 21
T171
Q
P
E
E
S
L
K
T
D
H
P
E
I
G
E
Site 22
T182
E
I
G
E
G
K
P
T
P
A
L
S
E
E
A
Site 23
S186
G
K
P
T
P
A
L
S
E
E
A
S
S
S
S
Site 24
S190
P
A
L
S
E
E
A
S
S
S
S
I
R
E
R
Site 25
S192
L
S
E
E
A
S
S
S
S
I
R
E
R
P
P
Site 26
S193
S
E
E
A
S
S
S
S
I
R
E
R
P
P
E
Site 27
S219
Q
E
Q
V
K
I
E
S
L
A
K
S
L
E
D
Site 28
S223
K
I
E
S
L
A
K
S
L
E
D
A
L
R
Q
Site 29
T231
L
E
D
A
L
R
Q
T
A
S
V
T
L
Q
A
Site 30
S263
L
K
A
A
M
D
N
S
E
I
A
G
E
K
K
Site 31
S271
E
I
A
G
E
K
K
S
A
Q
W
R
T
V
E
Site 32
T276
K
K
S
A
Q
W
R
T
V
E
G
A
L
K
E
Site 33
S307
E
E
L
E
K
M
K
S
V
I
E
N
A
K
K
Site 34
S356
Q
S
E
A
K
V
V
S
Q
Y
H
E
L
V
V
Site 35
T377
K
R
E
L
D
S
I
T
P
E
V
L
P
G
W
Site 36
S388
L
P
G
W
K
G
M
S
V
S
D
L
A
D
K
Site 37
S390
G
W
K
G
M
S
V
S
D
L
A
D
K
L
S
Site 38
S397
S
D
L
A
D
K
L
S
T
D
D
L
N
S
L
Site 39
S403
L
S
T
D
D
L
N
S
L
I
A
H
A
H
R
Site 40
T431
A
T
E
K
Q
H
I
T
L
A
L
E
K
Q
K
Site 41
S447
E
E
K
R
A
F
D
S
A
V
A
K
A
L
E
Site 42
S458
K
A
L
E
H
H
R
S
E
I
Q
A
E
Q
D
Site 43
S507
V
Q
E
Q
E
L
K
S
E
F
E
Q
N
L
S
Site 44
S514
S
E
F
E
Q
N
L
S
E
K
L
S
E
Q
E
Site 45
S518
Q
N
L
S
E
K
L
S
E
Q
E
L
Q
F
R
Site 46
S528
E
L
Q
F
R
R
L
S
Q
E
Q
V
D
N
F
Site 47
T536
Q
E
Q
V
D
N
F
T
L
D
I
N
T
A
Y
Site 48
Y543
T
L
D
I
N
T
A
Y
A
R
L
R
G
I
E
Site 49
S572
K
A
H
Q
L
W
L
S
V
E
A
L
K
Y
S
Site 50
Y578
L
S
V
E
A
L
K
Y
S
M
K
T
S
S
A
Site 51
S579
S
V
E
A
L
K
Y
S
M
K
T
S
S
A
E
Site 52
S583
L
K
Y
S
M
K
T
S
S
A
E
T
P
T
I
Site 53
T587
M
K
T
S
S
A
E
T
P
T
I
P
L
G
S
Site 54
S604
E
A
I
K
A
N
C
S
D
N
E
F
T
Q
A
Site 55
S620
T
A
A
I
P
P
E
S
L
T
R
G
V
Y
S
Site 56
Y626
E
S
L
T
R
G
V
Y
S
E
E
T
L
R
A
Site 57
T630
R
G
V
Y
S
E
E
T
L
R
A
R
F
Y
A
Site 58
Y636
E
T
L
R
A
R
F
Y
A
V
Q
K
L
A
R
Site 59
T651
R
V
A
M
I
D
E
T
R
N
S
L
Y
Q
Y
Site 60
S654
M
I
D
E
T
R
N
S
L
Y
Q
Y
F
L
S
Site 61
Y656
D
E
T
R
N
S
L
Y
Q
Y
F
L
S
Y
L
Site 62
Y658
T
R
N
S
L
Y
Q
Y
F
L
S
Y
L
Q
S
Site 63
Y693
N
T
F
K
L
L
S
Y
A
S
Y
C
I
E
H
Site 64
S695
F
K
L
L
S
Y
A
S
Y
C
I
E
H
G
D
Site 65
Y696
K
L
L
S
Y
A
S
Y
C
I
E
H
G
D
L
Site 66
S717
V
N
Q
L
K
G
E
S
R
R
V
A
Q
D
W
Site 67
T731
W
L
K
E
A
R
M
T
L
E
T
K
Q
I
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation