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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGT8
Full Name:
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
Alias:
2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; CGT; EC 2.4.1.45; UDP glycosyltransferase 8 (UDP-galactose ceramidegalactosyltransferase)
Type:
Transferase
Mass (Da):
61456
Number AA:
541
UniProt ID:
Q16880
International Prot ID:
IPI00294455
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0003851
GO:0008489
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0008152
GO:0007422
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T52
L
H
E
R
G
H
H
T
V
F
L
L
S
E
G
Site 2
S65
E
G
R
D
I
A
P
S
N
H
Y
S
L
Q
R
Site 3
S69
I
A
P
S
N
H
Y
S
L
Q
R
Y
P
G
I
Site 4
Y73
N
H
Y
S
L
Q
R
Y
P
G
I
F
N
S
T
Site 5
S79
R
Y
P
G
I
F
N
S
T
T
S
D
A
F
L
Site 6
T81
P
G
I
F
N
S
T
T
S
D
A
F
L
Q
S
Site 7
S82
G
I
F
N
S
T
T
S
D
A
F
L
Q
S
K
Site 8
S88
T
S
D
A
F
L
Q
S
K
M
R
N
I
F
S
Site 9
S95
S
K
M
R
N
I
F
S
G
R
L
T
A
I
E
Site 10
Y110
L
F
D
I
L
D
H
Y
T
K
N
C
D
L
M
Site 11
T185
P
E
F
N
S
L
L
T
D
R
M
N
L
L
Q
Site 12
Y215
S
F
L
V
L
P
K
Y
E
R
I
M
Q
K
Y
Site 13
Y222
Y
E
R
I
M
Q
K
Y
N
L
L
P
E
K
S
Site 14
S229
Y
N
L
L
P
E
K
S
M
Y
D
L
V
H
G
Site 15
Y231
L
L
P
E
K
S
M
Y
D
L
V
H
G
S
S
Site 16
S270
G
I
L
T
K
P
A
S
P
L
P
E
D
L
Q
Site 17
Y299
S
F
G
A
G
V
K
Y
L
S
E
D
I
A
N
Site 18
S301
G
A
G
V
K
Y
L
S
E
D
I
A
N
K
L
Site 19
S324
Q
K
V
I
W
R
F
S
G
P
K
P
K
N
L
Site 20
Y384
I
P
L
F
G
D
H
Y
D
T
M
T
R
V
Q
Site 21
T386
L
F
G
D
H
Y
D
T
M
T
R
V
Q
A
K
Site 22
T388
G
D
H
Y
D
T
M
T
R
V
Q
A
K
G
M
Site 23
T403
G
I
L
L
E
W
K
T
V
T
E
K
E
L
Y
Site 24
S421
V
K
V
I
N
N
P
S
Y
R
Q
R
A
Q
K
Site 25
Y422
K
V
I
N
N
P
S
Y
R
Q
R
A
Q
K
L
Site 26
S430
R
Q
R
A
Q
K
L
S
E
I
H
K
D
Q
P
Site 27
Y450
R
T
I
Y
W
I
D
Y
I
I
R
H
N
G
A
Site 28
Y500
S
W
V
T
K
F
I
Y
R
K
I
K
S
L
W
Site 29
S508
R
K
I
K
S
L
W
S
R
N
K
H
S
T
V
Site 30
Y519
H
S
T
V
N
G
H
Y
H
N
G
I
L
N
G
Site 31
Y528
N
G
I
L
N
G
K
Y
K
R
N
G
H
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation