PhosphoNET

           
Protein Info 
   
Short Name:  CA9
Full Name:  Carbonic anhydrase 9
Alias:  CAH9; CAIX; CA-IX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Carbonic dehydratase; EC 4.2.1.1; G250; Membrane MN; MN; P54/58N; RCC-associated G250; RCC-associated protein G250; Renal cell carcinoma-associated G250
Type:  Lyase, Energy Metabolism group, Nitrogen metabolism family
Mass (Da):  49698
Number AA:  459
UniProt ID:  Q16790
International Prot ID:  IPI00003966
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0042995  GO:0016021  GO:0005730 Uniprot OncoNet
Molecular Function:  GO:0004089  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0006730     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S47LPRMQEDSPLGGGSS
Site 2S54SPLGGGSSGEDDPLG
Site 3S67LGEEDLPSEEDSPRE
Site 4S71DLPSEEDSPREEDPP
Site 5S102LPEVKPKSEEEGSLK
Site 6S107PKSEEEGSLKLEDLP
Site 7T115LKLEDLPTVEAPGDP
Site 8S153DPPWPRVSPACAGRF
Site 9S162ACAGRFQSPVDIRPQ
Site 10S201RLRNNGHSVQLTLPP
Site 11T205NGHSVQLTLPPGLEM
Site 12Y220ALGPGREYRALQLHL
Site 13S237GAAGRPGSEHTVEGH
Site 14T240GRPGSEHTVEGHRFP
Site 15S287EEGPEENSAYEQLLS
Site 16Y289GPEENSAYEQLLSRL
Site 17S294SAYEQLLSRLEEIAE
Site 18T306IAEEGSETQVPGLDI
Site 19S319DISALLPSDFSRYFQ
Site 20Y324LPSDFSRYFQYEGSL
Site 21T332FQYEGSLTTPPCAQG
Site 22T333QYEGSLTTPPCAQGV
Site 23T358LSAKQLHTLSDTLWG
Site 24S360AKQLHTLSDTLWGPG
Site 25T362QLHTLSDTLWGPGDS
Site 26T378LQLNFRATQPLNGRV
Site 27S389NGRVIEASFPAGVDS
Site 28S396SFPAGVDSSPRAAEP
Site 29S397FPAGVDSSPRAAEPV
Site 30T443RRQHRRGTKGGVSYR
Site 31S448RGTKGGVSYRPAEVA
Site 32Y449GTKGGVSYRPAEVAE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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