PhosphoNET

           
Protein Info 
   
Short Name:  FXN
Full Name:  Frataxin, mitochondrial
Alias:  Friedreich ataxia protein;m56-FXN;d-FXN;m78-FXN;Frataxin(81-210);m81-FXN
Type: 
Mass (Da):  23135
Number AA:  210
UniProt ID:  Q16595
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T23PSPAQAQTLTRVPRP
Site 2T25PAQAQTLTRVPRPAE
Site 3T44CGRRGLRTDIDATCT
Site 4T49LRTDIDATCTPRRAS
Site 5T51TDIDATCTPRRASSN
Site 6S56TCTPRRASSNQRGLN
Site 7S57CTPRRASSNQRGLNQ
Site 8S81YLMNLRKSGTLGHPG
Site 9T83MNLRKSGTLGHPGSL
Site 10S89GTLGHPGSLDETTYE
Site 11T93HPGSLDETTYERLAE
Site 12T94PGSLDETTYERLAEE
Site 13Y95GSLDETTYERLAEET
Site 14T102YERLAEETLDSLAEF
Site 15S105LAEETLDSLAEFFED
Site 16Y118EDLADKPYTFEDYDV
Site 17T119DLADKPYTFEDYDVS
Site 18Y123KPYTFEDYDVSFGSG
Site 19Y143LGGDLGTYVINKQTP
Site 20T149TYVINKQTPNKQIWL
Site 21S157PNKQIWLSSPSSGPK
Site 22S158NKQIWLSSPSSGPKR
Site 23S160QIWLSSPSSGPKRYD
Site 24S161IWLSSPSSGPKRYDW
Site 25Y166PSSGPKRYDWTGKNW
Site 26Y175WTGKNWVYSHDGVSL
Site 27T196ELTKALKTKLDLSSL
Site 28S201LKTKLDLSSLAYSGK
Site 29S202KTKLDLSSLAYSGKD
Site 30Y205LDLSSLAYSGKDA__
Site 31S206DLSSLAYSGKDA___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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