PhosphoNET

           
Protein Info 
   
Short Name:  HLF
Full Name:  Hepatic leukemia factor
Alias: 
Type: 
Mass (Da):  33199
Number AA:  295
UniProt ID:  Q16534
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T13RPLPLNPTFIPPPYG
Site 2S24PPYGVLRSLLENPLK
Site 3S41LHHEDAFSKDKDKEK
Site 4S54EKKLDDESNSPTVPQ
Site 5S56KLDDESNSPTVPQSA
Site 6T58DDESNSPTVPQSAFL
Site 7S62NSPTVPQSAFLGPTL
Site 8T73GPTLWDKTLPYDGDT
Site 9Y76LWDKTLPYDGDTFQL
Site 10T80TLPYDGDTFQLEYMD
Site 11Y85GDTFQLEYMDLEEFL
Site 12S93MDLEEFLSENGIPPS
Site 13S100SENGIPPSPSQHDHS
Site 14S102NGIPPSPSQHDHSPH
Site 15S107SPSQHDHSPHPPGLQ
Site 16S117PPGLQPASSAAPSVM
Site 17S118PGLQPASSAAPSVMD
Site 18S122PASSAAPSVMDLSSR
Site 19S128PSVMDLSSRASAPLH
Site 20S131MDLSSRASAPLHPGI
Site 21S140PLHPGIPSPNCMQSP
Site 22S146PSPNCMQSPIRPGQL
Site 23T160LLPANRNTPSPIDPD
Site 24S162PANRNTPSPIDPDTI
Site 25T168PSPIDPDTIQVPVGY
Site 26S185DPADLALSSIPGQEM
Site 27S201DPRKRKFSEEELKPQ
Site 28Y228DDLKDDKYWARRRKN
Site 29S258NQIAIRASFLEKENS
Site 30S265SFLEKENSALRQEVA
Site 31Y288CKNILAKYEARHGPL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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