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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRIK5
Full Name:
Glutamate receptor, ionotropic kainate 5
Alias:
Excitatory amino acid receptor 2;Glutamate receptor KA-2
Type:
Mass (Da):
109265
Number AA:
980
UniProt ID:
Q16478
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
A
A
I
L
D
D
Q
T
V
C
G
R
G
E
R
Site 2
S74
I
F
E
L
Q
R
D
S
Q
Y
E
T
T
D
T
Site 3
Y76
E
L
Q
R
D
S
Q
Y
E
T
T
D
T
M
C
Site 4
T81
S
Q
Y
E
T
T
D
T
M
C
Q
I
L
P
K
Site 5
S102
G
P
S
S
S
P
A
S
A
S
T
V
S
H
I
Site 6
S104
S
S
S
P
A
S
A
S
T
V
S
H
I
C
G
Site 7
T105
S
S
P
A
S
A
S
T
V
S
H
I
C
G
E
Site 8
T125
I
K
V
G
P
E
E
T
P
R
L
Q
Y
L
R
Site 9
Y130
E
E
T
P
R
L
Q
Y
L
R
F
A
S
V
S
Site 10
S135
L
Q
Y
L
R
F
A
S
V
S
L
Y
P
S
N
Site 11
S137
Y
L
R
F
A
S
V
S
L
Y
P
S
N
E
D
Site 12
Y139
R
F
A
S
V
S
L
Y
P
S
N
E
D
V
S
Site 13
S141
A
S
V
S
L
Y
P
S
N
E
D
V
S
L
A
Site 14
S146
Y
P
S
N
E
D
V
S
L
A
V
S
R
I
L
Site 15
S155
A
V
S
R
I
L
K
S
F
N
Y
P
S
A
S
Site 16
S162
S
F
N
Y
P
S
A
S
L
I
C
A
K
A
E
Site 17
S189
L
I
S
K
E
T
L
S
V
R
M
L
D
D
S
Site 18
S196
S
V
R
M
L
D
D
S
R
D
P
T
P
L
L
Site 19
T200
L
D
D
S
R
D
P
T
P
L
L
K
E
I
R
Site 20
S212
E
I
R
D
D
K
V
S
T
I
I
I
D
A
N
Site 21
T236
K
A
S
E
L
G
M
T
S
A
F
Y
K
Y
I
Site 22
S268
S
S
N
I
L
G
F
S
M
F
N
T
S
H
P
Site 23
T272
L
G
F
S
M
F
N
T
S
H
P
F
Y
P
E
Site 24
Y277
F
N
T
S
H
P
F
Y
P
E
F
V
R
S
L
Site 25
Y297
E
N
C
E
A
S
T
Y
L
G
P
A
L
S
A
Site 26
S324
A
V
R
E
L
N
R
S
Q
E
I
G
V
K
P
Site 27
Y349
H
G
T
S
L
M
N
Y
L
R
M
V
E
Y
D
Site 28
Y355
N
Y
L
R
M
V
E
Y
D
G
L
T
G
R
V
Site 29
T359
M
V
E
Y
D
G
L
T
G
R
V
E
F
N
S
Site 30
S366
T
G
R
V
E
F
N
S
K
G
Q
R
T
N
Y
Site 31
Y373
S
K
G
Q
R
T
N
Y
T
L
R
I
L
E
K
Site 32
T374
K
G
Q
R
T
N
Y
T
L
R
I
L
E
K
S
Site 33
S381
T
L
R
I
L
E
K
S
R
Q
G
H
R
E
I
Site 34
Y392
H
R
E
I
G
V
W
Y
S
N
R
T
L
A
M
Site 35
S409
T
T
L
D
I
N
L
S
Q
T
L
A
N
K
T
Site 36
Y427
T
T
I
L
E
N
P
Y
V
M
R
R
P
N
F
Site 37
S438
R
P
N
F
Q
A
L
S
G
N
E
R
F
E
G
Site 38
Y462
A
E
L
L
R
F
R
Y
R
L
R
L
V
E
D
Site 39
Y472
R
L
V
E
D
G
L
Y
G
A
P
E
P
N
G
Site 40
S480
G
A
P
E
P
N
G
S
W
T
G
M
V
G
E
Site 41
S513
R
E
K
V
I
D
F
S
K
P
F
M
T
L
G
Site 42
Y535
H
M
G
R
K
P
G
Y
F
S
F
L
D
P
F
Site 43
S537
G
R
K
P
G
Y
F
S
F
L
D
P
F
S
P
Site 44
S568
L
F
L
A
A
R
L
S
P
Y
E
W
Y
N
P
Site 45
Y570
L
A
A
R
L
S
P
Y
E
W
Y
N
P
H
P
Site 46
Y590
P
H
I
L
E
N
Q
Y
T
L
G
N
S
L
W
Site 47
S608
G
G
F
M
Q
Q
G
S
E
I
M
P
R
A
L
Site 48
T662
A
D
D
L
A
D
Q
T
N
I
E
Y
G
T
I
Site 49
T676
I
H
A
G
S
T
M
T
F
F
Q
N
S
R
Y
Site 50
S699
Y
M
Q
S
K
Q
P
S
V
F
V
K
S
T
E
Site 51
Y728
L
E
S
T
M
N
E
Y
H
R
R
L
N
C
N
Site 52
T737
R
R
L
N
C
N
L
T
Q
I
G
G
L
L
D
Site 53
S756
G
I
G
M
P
L
G
S
P
F
R
D
E
I
T
Site 54
S829
A
V
M
E
F
I
W
S
T
R
R
S
A
E
S
Site 55
S833
F
I
W
S
T
R
R
S
A
E
S
E
E
V
S
Site 56
S836
S
T
R
R
S
A
E
S
E
E
V
S
V
C
Q
Site 57
S840
S
A
E
S
E
E
V
S
V
C
Q
E
M
L
Q
Site 58
S854
Q
E
L
R
H
A
V
S
C
R
K
T
S
R
S
Site 59
T858
H
A
V
S
C
R
K
T
S
R
S
R
R
R
R
Site 60
S859
A
V
S
C
R
K
T
S
R
S
R
R
R
R
R
Site 61
S861
S
C
R
K
T
S
R
S
R
R
R
R
R
P
G
Site 62
S871
R
R
R
P
G
G
P
S
R
A
L
L
S
L
R
Site 63
S876
G
P
S
R
A
L
L
S
L
R
A
V
R
E
M
Site 64
S886
A
V
R
E
M
R
L
S
N
G
K
L
Y
S
A
Site 65
Y891
R
L
S
N
G
K
L
Y
S
A
G
A
G
G
D
Site 66
S892
L
S
N
G
K
L
Y
S
A
G
A
G
G
D
A
Site 67
S901
G
A
G
G
D
A
G
S
A
H
G
G
P
Q
R
Site 68
S917
L
D
D
P
G
P
P
S
G
A
R
P
A
A
P
Site 69
T925
G
A
R
P
A
A
P
T
P
C
T
H
V
R
V
Site 70
T928
P
A
A
P
T
P
C
T
H
V
R
V
C
Q
E
Site 71
S945
R
I
Q
A
L
R
A
S
G
A
G
A
P
P
R
Site 72
T961
L
G
V
P
A
E
A
T
S
P
P
R
P
R
P
Site 73
S962
G
V
P
A
E
A
T
S
P
P
R
P
R
P
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation