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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNGA3
Full Name:
Cyclic nucleotide-gated cation channel alpha-3
Alias:
Cone photoreceptor cGMP-gated channel subunit alpha;Cyclic nucleotide-gated channel alpha-3
Type:
Mass (Da):
78838
Number AA:
694
UniProt ID:
Q16281
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
K
I
N
T
Q
Y
S
H
P
S
R
T
H
Site 2
S9
A
K
I
N
T
Q
Y
S
H
P
S
R
T
H
L
Site 3
T20
R
T
H
L
K
V
K
T
S
D
R
D
L
N
R
Site 4
S21
T
H
L
K
V
K
T
S
D
R
D
L
N
R
A
Site 5
S33
N
R
A
E
N
G
L
S
R
A
H
S
S
S
E
Site 6
S37
N
G
L
S
R
A
H
S
S
S
E
E
T
S
S
Site 7
S38
G
L
S
R
A
H
S
S
S
E
E
T
S
S
V
Site 8
S39
L
S
R
A
H
S
S
S
E
E
T
S
S
V
L
Site 9
T42
A
H
S
S
S
E
E
T
S
S
V
L
Q
P
G
Site 10
S43
H
S
S
S
E
E
T
S
S
V
L
Q
P
G
I
Site 11
S44
S
S
S
E
E
T
S
S
V
L
Q
P
G
I
A
Site 12
S60
E
T
R
G
L
A
D
S
G
Q
G
S
F
T
G
Site 13
S64
L
A
D
S
G
Q
G
S
F
T
G
Q
G
I
A
Site 14
S97
H
Q
D
Q
G
P
D
S
F
P
D
R
F
R
G
Site 15
S111
G
A
E
L
K
E
V
S
S
Q
E
S
N
A
Q
Site 16
S112
A
E
L
K
E
V
S
S
Q
E
S
N
A
Q
A
Site 17
S115
K
E
V
S
S
Q
E
S
N
A
Q
A
N
V
G
Site 18
S123
N
A
Q
A
N
V
G
S
Q
E
P
A
D
R
G
Site 19
S132
E
P
A
D
R
G
R
S
A
W
P
L
A
K
C
Site 20
S144
A
K
C
N
T
N
T
S
N
N
T
E
E
E
K
Site 21
T153
N
T
E
E
E
K
K
T
K
K
K
D
A
I
V
Site 22
Y168
V
D
P
S
S
N
L
Y
Y
R
W
L
T
A
I
Site 23
Y169
D
P
S
S
N
L
Y
Y
R
W
L
T
A
I
A
Site 24
S234
L
E
Q
G
L
M
V
S
D
T
N
R
L
W
Q
Site 25
Y243
T
N
R
L
W
Q
H
Y
K
T
T
T
Q
F
K
Site 26
T245
R
L
W
Q
H
Y
K
T
T
T
Q
F
K
L
D
Site 27
Y270
Y
L
K
V
G
T
N
Y
P
E
V
R
F
N
R
Site 28
S282
F
N
R
L
L
K
F
S
R
L
F
E
F
F
D
Site 29
T291
L
F
E
F
F
D
R
T
E
T
R
T
N
Y
P
Site 30
T293
E
F
F
D
R
T
E
T
R
T
N
Y
P
N
M
Site 31
Y297
R
T
E
T
R
T
N
Y
P
N
M
F
R
I
G
Site 32
T332
S
K
F
I
G
F
G
T
D
S
W
V
Y
P
N
Site 33
Y337
F
G
T
D
S
W
V
Y
P
N
I
S
I
P
E
Site 34
S349
I
P
E
H
G
R
L
S
R
K
Y
I
Y
S
L
Site 35
Y352
H
G
R
L
S
R
K
Y
I
Y
S
L
Y
W
S
Site 36
S355
L
S
R
K
Y
I
Y
S
L
Y
W
S
T
L
T
Site 37
Y357
R
K
Y
I
Y
S
L
Y
W
S
T
L
T
L
T
Site 38
T369
T
L
T
T
I
G
E
T
P
P
P
V
K
D
E
Site 39
S404
G
N
V
G
S
M
I
S
N
M
N
A
S
R
A
Site 40
S409
M
I
S
N
M
N
A
S
R
A
E
F
Q
A
K
Site 41
Y423
K
I
D
S
I
K
Q
Y
M
Q
F
R
K
V
T
Site 42
T430
Y
M
Q
F
R
K
V
T
K
D
L
E
T
R
V
Site 43
Y443
R
V
I
R
W
F
D
Y
L
W
A
N
K
K
T
Site 44
T450
Y
L
W
A
N
K
K
T
V
D
E
K
E
V
L
Site 45
S459
D
E
K
E
V
L
K
S
L
P
D
K
L
K
A
Site 46
S504
K
L
R
P
T
V
F
S
P
G
D
Y
I
C
K
Site 47
Y508
T
V
F
S
P
G
D
Y
I
C
K
K
G
D
I
Site 48
Y520
G
D
I
G
K
E
M
Y
I
I
N
E
G
K
L
Site 49
S558
S
I
L
N
I
K
G
S
K
S
G
N
R
R
T
Site 50
S560
L
N
I
K
G
S
K
S
G
N
R
R
T
A
N
Site 51
T565
S
K
S
G
N
R
R
T
A
N
I
R
S
I
G
Site 52
S570
R
R
T
A
N
I
R
S
I
G
Y
S
D
L
F
Site 53
S574
N
I
R
S
I
G
Y
S
D
L
F
C
L
S
K
Site 54
S580
Y
S
D
L
F
C
L
S
K
D
D
L
M
E
A
Site 55
T589
D
D
L
M
E
A
L
T
E
Y
P
E
A
K
K
Site 56
Y591
L
M
E
A
L
T
E
Y
P
E
A
K
K
A
L
Site 57
S635
E
K
V
E
Q
L
G
S
S
L
D
T
L
Q
T
Site 58
T639
Q
L
G
S
S
L
D
T
L
Q
T
R
F
A
R
Site 59
Y651
F
A
R
L
L
A
E
Y
N
A
T
Q
M
K
M
Site 60
T654
L
L
A
E
Y
N
A
T
Q
M
K
M
K
Q
R
Site 61
S663
M
K
M
K
Q
R
L
S
Q
L
E
S
Q
V
K
Site 62
S667
Q
R
L
S
Q
L
E
S
Q
V
K
G
G
G
D
Site 63
T689
V
P
G
D
A
T
K
T
E
D
K
Q
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation