PhosphoNET

           
Protein Info 
   
Short Name:  IGFBP7
Full Name:  Insulin-like growth factor-binding protein 7
Alias:  IGFBP-rP1;MAC25 protein;PGI2-stimulating factor;Prostacyclin-stimulating factor;Tumor-derived adhesion factor
Type: 
Mass (Da):  29130
Number AA:  282
UniProt ID:  Q16270
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S27LLPLSSSSSSDTCGP
Site 2S28LPLSSSSSSDTCGPC
Site 3S29PLSSSSSSDTCGPCE
Site 4T31SSSSSSDTCGPCEPA
Site 5Y80GGGAGRGYCAPGMEC
Site 6S90PGMECVKSRKRRKGK
Site 7T125PVCGSDGTTYPSGCQ
Site 8T126VCGSDGTTYPSGCQL
Site 9Y127CGSDGTTYPSGCQLR
Site 10S129SDGTTYPSGCQLRAA
Site 11S137GCQLRAASQRAESRG
Site 12S142AASQRAESRGEKAIT
Site 13T149SRGEKAITQVSKGTC
Site 14S161GTCEQGPSIVTPPKD
Site 15T164EQGPSIVTPPKDIWN
Site 16Y201NKVKRGHYGVQRTEL
Site 17S239WVLVSPLSKEDAGEY
Site 18Y246SKEDAGEYECHASNS
Site 19S251GEYECHASNSQGQAS
Site 20S253YECHASNSQGQASAS
Site 21S258SNSQGQASASAKITV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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