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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHRNA6
Full Name:
Neuronal acetylcholine receptor subunit alpha-6
Alias:
ACHA6; CHNRA6; cholinergic receptor, nicotinic, alpha 6; neuronal acetylcholine receptor subunit alpha-6
Type:
Channel, ligand-gated
Mass (Da):
56898
Number AA:
494
UniProt ID:
Q15825
International Prot ID:
IPI00019948
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005892
GO:0045211
Uniprot
OncoNet
Molecular Function:
GO:0015464
GO:0004889
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007165
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
K
G
C
V
G
C
A
T
E
E
R
L
F
H
K
Site 2
S56
I
R
P
V
E
N
V
S
D
P
V
T
V
H
F
Site 3
Y102
L
R
W
D
P
M
E
Y
D
G
I
E
T
L
R
Site 4
T107
M
E
Y
D
G
I
E
T
L
R
V
P
A
D
K
Site 5
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Site 6
Y142
K
T
K
A
L
L
K
Y
N
G
M
I
T
W
T
Site 7
T149
Y
N
G
M
I
T
W
T
P
P
A
I
F
K
S
Site 8
Y220
G
Y
K
H
D
I
K
Y
N
C
C
E
E
I
Y
Site 9
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Site 10
Y232
E
I
Y
T
D
I
T
Y
S
F
Y
I
R
R
L
Site 11
Y306
V
V
P
L
V
G
E
Y
L
L
F
T
M
I
F
Site 12
Y329
V
F
V
L
N
I
H
Y
R
T
P
T
T
H
T
Site 13
T331
V
L
N
I
H
Y
R
T
P
T
T
H
T
M
P
Site 14
T362
M
R
W
P
L
D
K
T
R
G
T
G
S
D
A
Site 15
T365
P
L
D
K
T
R
G
T
G
S
D
A
V
P
R
Site 16
S367
D
K
T
R
G
T
G
S
D
A
V
P
R
G
L
Site 17
S385
P
A
K
G
K
L
A
S
H
G
E
P
R
H
L
Site 18
S407
K
S
N
E
L
A
T
S
K
R
R
L
S
H
Q
Site 19
S412
A
T
S
K
R
R
L
S
H
Q
P
L
Q
W
V
Site 20
S426
V
V
E
N
S
E
H
S
P
E
V
E
D
V
I
Site 21
S435
E
V
E
D
V
I
N
S
V
Q
F
I
A
E
N
Site 22
S445
F
I
A
E
N
M
K
S
H
N
E
T
K
E
V
Site 23
T449
N
M
K
S
H
N
E
T
K
E
V
E
D
D
W
Site 24
Y458
E
V
E
D
D
W
K
Y
V
A
M
V
V
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation