PhosphoNET

           
Protein Info 
   
Short Name:  SLC9A3R2
Full Name:  Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Alias:  E3KARP; Na( )/H( ) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein E3KARP; NHERF-2; NHR2; NHRF2; SIP- 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 2; Solute carrier family 9 isoform A3 regulatory factor 2; SRY interacting protein 1; TKA-1; Tyrosine kinase activator protein 1
Type:  Adapter/scaffold protein
Mass (Da):  37414
Number AA:  337
UniProt ID:  Q15599
International Prot ID:  IPI00385034
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0019898  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0008022     PhosphoSite+ KinaseNET
Biological Process:  GO:0006461     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y21LVRGEQGYGFHLHGE
Site 2S43IRRVEPGSPAEAAAL
Site 3T102ELRRRQLTCTEEMAQ
Site 4T104RRRQLTCTEEMAQRG
Site 5T128PKPDWAHTGSHSSEA
Site 6S130PDWAHTGSHSSEAGK
Site 7S133AHTGSHSSEAGKKDV
Site 8S167GYGFNLHSDKSRPGQ
Site 9S170FNLHSDKSRPGQYIR
Site 10Y175DKSRPGQYIRSVDPG
Site 11S178RPGQYIRSVDPGSPA
Site 12S183IRSVDPGSPAARSGL
Site 13S188PGSPAARSGLRAQDR
Site 14S215RHAEVVASIKAREDE
Site 15T232LLVVDPETDEHFKRL
Site 16T242HFKRLRVTPTEEHVE
Site 17S254HVEGPLPSPVTNGTS
Site 18T257GPLPSPVTNGTSPAQ
Site 19T260PSPVTNGTSPAQLNG
Site 20S261SPVTNGTSPAQLNGG
Site 21S269PAQLNGGSACSSRSD
Site 22S272LNGGSACSSRSDLPG
Site 23S273NGGSACSSRSDLPGS
Site 24S275GSACSSRSDLPGSDK
Site 25S280SRSDLPGSDKDTEDG
Site 26T284LPGSDKDTEDGSAWK
Site 27S303QESGLHLSPTAAEAK
Site 28T305SGLHLSPTAAEAKEK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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