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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYTH1
Full Name:
Cytohesin-1
Alias:
B2-1; CYH1; Cytoadhesin 1; Cytohesin 1; D17S811E; PSCD1; SEC7
Type:
Guanine nucleotide exchange factor, ARF
Mass (Da):
46413
Number AA:
398
UniProt ID:
Q15438
International Prot ID:
IPI00478608
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005086
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032012
GO:0030155
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
E
D
D
S
Y
V
P
S
D
L
T
Site 2
Y7
_
M
E
E
D
D
S
Y
V
P
S
D
L
T
A
Site 3
S10
E
D
D
S
Y
V
P
S
D
L
T
A
E
E
R
Site 4
T13
S
Y
V
P
S
D
L
T
A
E
E
R
Q
E
L
Site 5
S53
N
E
I
E
N
L
G
S
T
E
E
R
K
N
M
Site 6
T54
E
I
E
N
L
G
S
T
E
E
R
K
N
M
Q
Site 7
Y102
E
D
I
A
Q
F
L
Y
K
G
E
G
L
N
K
Site 8
T110
K
G
E
G
L
N
K
T
A
I
G
D
Y
L
G
Site 9
Y115
N
K
T
A
I
G
D
Y
L
G
E
R
D
E
F
Site 10
S151
A
L
R
Q
F
L
W
S
F
R
L
P
G
E
A
Site 11
T210
P
N
V
K
D
K
P
T
V
E
R
F
I
A
M
Site 12
Y236
E
E
L
L
R
N
L
Y
E
S
I
K
N
E
P
Site 13
S238
L
L
R
N
L
Y
E
S
I
K
N
E
P
F
K
Site 14
T255
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Site 15
T257
D
G
N
D
L
T
H
T
F
F
N
P
D
R
E
Site 16
T277
L
G
G
G
R
V
K
T
W
K
R
R
W
F
I
Site 17
Y291
I
L
T
D
N
C
L
Y
Y
F
E
Y
T
T
D
Site 18
Y292
L
T
D
N
C
L
Y
Y
F
E
Y
T
T
D
K
Site 19
Y295
N
C
L
Y
Y
F
E
Y
T
T
D
K
E
P
R
Site 20
S311
I
I
P
L
E
N
L
S
I
R
E
V
E
D
S
Site 21
S318
S
I
R
E
V
E
D
S
K
K
P
N
C
F
E
Site 22
Y327
K
P
N
C
F
E
L
Y
I
P
D
N
K
D
Q
Site 23
T353
R
V
V
E
G
N
H
T
V
Y
R
I
S
A
P
Site 24
Y355
V
E
G
N
H
T
V
Y
R
I
S
A
P
T
P
Site 25
S358
N
H
T
V
Y
R
I
S
A
P
T
P
E
E
K
Site 26
T361
V
Y
R
I
S
A
P
T
P
E
E
K
E
E
W
Site 27
Y382
A
I
S
R
D
P
F
Y
E
M
L
A
A
R
K
Site 28
S393
A
A
R
K
K
K
V
S
S
T
K
R
H
_
_
Site 29
S394
A
R
K
K
K
V
S
S
T
K
R
H
_
_
_
Site 30
T395
R
K
K
K
V
S
S
T
K
R
H
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation