KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SEC23B
Full Name:
Protein transport protein Sec23B
Alias:
SEC23-related protein B
Type:
Mass (Da):
86461
Number AA:
767
UniProt ID:
Q15437
International Prot ID:
IPI00017376
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005794
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0006888
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
E
R
D
G
V
R
F
S
W
N
V
W
P
S
S
Site 2
S27
S
W
N
V
W
P
S
S
R
L
E
A
T
R
M
Site 3
Y56
P
D
L
P
P
V
Q
Y
E
P
V
L
C
S
R
Site 4
Y78
N
P
L
C
Q
V
D
Y
R
A
K
L
W
A
C
Site 5
Y98
R
N
Q
F
P
P
A
Y
G
G
I
S
E
V
N
Site 6
S102
P
P
A
Y
G
G
I
S
E
V
N
Q
P
A
E
Site 7
Y119
P
Q
F
S
T
I
E
Y
V
I
Q
R
G
A
Q
Site 8
S150
D
L
Q
A
L
K
E
S
L
Q
M
S
L
S
L
Site 9
S154
L
K
E
S
L
Q
M
S
L
S
L
L
P
P
D
Site 10
S179
M
V
Q
V
H
E
L
S
C
E
G
I
S
K
S
Site 11
S186
S
C
E
G
I
S
K
S
Y
V
F
R
G
T
K
Site 12
Y187
C
E
G
I
S
K
S
Y
V
F
R
G
T
K
D
Site 13
T192
K
S
Y
V
F
R
G
T
K
D
L
T
A
K
Q
Site 14
T196
F
R
G
T
K
D
L
T
A
K
Q
I
Q
D
M
Site 15
S228
P
Q
E
H
P
F
A
S
S
R
F
L
Q
P
V
Site 16
T257
Q
R
D
P
W
P
V
T
Q
G
K
R
P
L
R
Site 17
S265
Q
G
K
R
P
L
R
S
T
G
V
A
L
S
I
Site 18
S378
G
Y
M
V
M
G
D
S
F
N
T
S
L
F
K
Site 19
T381
V
M
G
D
S
F
N
T
S
L
F
K
Q
T
F
Site 20
S382
M
G
D
S
F
N
T
S
L
F
K
Q
T
F
Q
Site 21
T387
N
T
S
L
F
K
Q
T
F
Q
R
I
F
T
K
Site 22
T393
Q
T
F
Q
R
I
F
T
K
D
F
N
G
D
F
Site 23
T407
F
R
M
A
F
G
A
T
L
D
V
K
T
S
R
Site 24
T412
G
A
T
L
D
V
K
T
S
R
E
L
K
I
A
Site 25
S413
A
T
L
D
V
K
T
S
R
E
L
K
I
A
G
Site 26
S436
N
V
K
G
P
C
V
S
E
N
E
L
G
V
G
Site 27
Y462
P
T
S
T
L
G
I
Y
F
E
V
V
N
Q
H
Site 28
T471
E
V
V
N
Q
H
N
T
P
I
P
Q
G
G
R
Site 29
T485
R
G
A
I
Q
F
V
T
H
Y
Q
H
S
S
T
Site 30
Y487
A
I
Q
F
V
T
H
Y
Q
H
S
S
T
Q
R
Site 31
S491
V
T
H
Y
Q
H
S
S
T
Q
R
R
I
R
V
Site 32
T492
T
H
Y
Q
H
S
S
T
Q
R
R
I
R
V
T
Site 33
T499
T
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
Site 34
T500
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Site 35
S510
R
N
W
A
D
V
Q
S
Q
L
R
H
I
E
A
Site 36
S538
L
G
V
F
R
A
E
S
E
E
G
P
D
V
L
Site 37
S569
Y
N
K
E
D
P
T
S
F
R
L
S
D
S
F
Site 38
S573
D
P
T
S
F
R
L
S
D
S
F
S
L
Y
P
Site 39
S575
T
S
F
R
L
S
D
S
F
S
L
Y
P
Q
F
Site 40
S598
F
L
Q
V
F
N
N
S
P
D
E
S
S
Y
Y
Site 41
Y604
N
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Site 42
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Site 43
T615
H
F
A
R
Q
D
L
T
Q
S
L
I
M
I
Q
Site 44
Y628
I
Q
P
I
L
Y
S
Y
S
F
H
G
P
P
E
Site 45
S629
Q
P
I
L
Y
S
Y
S
F
H
G
P
P
E
P
Site 46
S641
P
E
P
V
L
L
D
S
S
S
I
L
A
D
R
Site 47
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Site 48
Y707
A
R
F
P
M
P
R
Y
I
N
T
E
H
G
G
Site 49
T710
P
M
P
R
Y
I
N
T
E
H
G
G
S
Q
A
Site 50
S715
I
N
T
E
H
G
G
S
Q
A
R
F
L
L
S
Site 51
S722
S
Q
A
R
F
L
L
S
K
V
N
P
S
Q
T
Site 52
S727
L
L
S
K
V
N
P
S
Q
T
H
N
N
L
Y
Site 53
T729
S
K
V
N
P
S
Q
T
H
N
N
L
Y
A
W
Site 54
Y734
S
Q
T
H
N
N
L
Y
A
W
G
Q
E
T
G
Site 55
T740
L
Y
A
W
G
Q
E
T
G
A
P
I
L
T
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation