PhosphoNET

           
Protein Info 
   
Short Name:  PLEC1
Full Name:  Plectin
Alias:  EBS1; Expressed sequence AA591047; HD1; Hemidesmosomal protein 1; PCN; Plectin 1, intermediate filament binding protein 500kDa; Plectin-11; PLTN
Type:  Cytoskeletal protein
Mass (Da):  531791
Number AA:  4684
UniProt ID:  Q15149
International Prot ID:  IPI00014898
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005856  GO:0005829  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0003779  GO:0008307  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y16RDQLRAIYEVLFREG
Site 2S35KKDRRPRSLHPHVPG
Site 3Y85GIAHLRQYLHLPPEI
Site 4S96PPEIVPASLQRVRRP
Site 5T113MVMPARRTPHVQAVQ
Site 6S125AVQGPLGSPPKRGPL
Site 7T134PKRGPLPTEEQRVYR
Site 8Y140PTEEQRVYRRKELEE
Site 9S149RKELEEVSPETPVVP
Site 10T152LEEVSPETPVVPATT
Site 11T158ETPVVPATTQRTLAR
Site 12T174GPEPAPATDERDRVQ
Site 13T184RDRVQKKTFTKWVNK
Site 14S201IKAQRHISDLYEDLR
Site 15Y204QRHISDLYEDLRDGH
Site 16S224LEVLSGDSLPREKGR
Site 17Y246NVQIALDYLRHRQVK
Site 18S284IILHFQISDIQVSGQ
Site 19T296SGQSEDMTAKEKLLL
Site 20S305KEKLLLWSQRMVEGY
Site 21Y312SQRMVEGYQGLRCDN
Site 22T321GLRCDNFTSSWRDGR
Site 23S322LRCDNFTSSWRDGRL
Site 24T351MNKVYRQTNLENLDQ
Site 25S361ENLDQAFSVAERDLG
Site 26S387VPQPDEKSIITYVSS
Site 27T390PDEKSIITYVSSLYD
Site 28Y391DEKSIITYVSSLYDA
Site 29Y396ITYVSSLYDAMPRVP
Site 30T436LQWMRHHTAAFEERR
Site 31S446FEERRFPSSFEEIEI
Site 32S447EERRFPSSFEEIEIL
Site 33S456EEIEILWSQFLKFKE
Site 34Y480KNRSKGIYQSLEGAV
Site 35S482RSKGIYQSLEGAVQA
Site 36S523EREKQLRSEFERLEC
Site 37T536ECLQRIVTKLQMEAG
Site 38S584RDLDKADSMIRLLFN
Site 39T595LLFNDVQTLKDGRHP
Site 40Y608HPQGEQMYRRVYRLH
Site 41Y612EQMYRRVYRLHERLV
Site 42S647VAQVTLQSVQRRPEL
Site 43S657RRPELEDSTLRYLQD
Site 44T658RPELEDSTLRYLQDL
Site 45Y661LEDSTLRYLQDLLAW
Site 46S687EWGVDLPSVEAQLGS
Site 47S694SVEAQLGSHRGLHQS
Site 48S701SHRGLHQSIEEFRAK
Site 49S714AKIERARSDEGQLSP
Site 50S720RSDEGQLSPATRGAY
Site 51Y727SPATRGAYRDCLGRL
Site 52Y738LGRLDLQYAKLLNSS
Site 53S751SSKARLRSLESLHSF
Site 54S757RSLESLHSFVAAATK
Site 55S782EEVGFDWSDRNTNMT
Site 56T789SDRNTNMTAKKESYS
Site 57T829EDHPARPTVESFQAA
Site 58S832PARPTVESFQAALQT
Site 59Y861HLKENAAYFQFFSDV
Site 60S866AAYFQFFSDVREAEG
Site 61Y886QEALRRKYSCDRSAT
Site 62S887EALRRKYSCDRSATV
Site 63S891RKYSCDRSATVTRLE
Site 64T893YSCDRSATVTRLEDL
Site 65T895CDRSATVTRLEDLLQ
Site 66Y914EKEQLNEYKGHLSGL
Site 67S919NEYKGHLSGLAKRAK
Site 68T958DYKQVEVTVHKGDEC
Site 69S974LVGPAQPSHWKVLSS
Site 70S980PSHWKVLSSSGSEAA
Site 71S981SHWKVLSSSGSEAAV
Site 72S1035KSLLAWQSLRRDVQL
Site 73S1045RDVQLIRSWSLATFR
Site 74S1047VQLIRSWSLATFRTL
Site 75T1050IRSWSLATFRTLKPE
Site 76T1053WSLATFRTLKPEEQR
Site 77S1065EQRQALHSLELHYQA
Site 78S1077YQAFLRDSQDAGGFG
Site 79Y1095RLMAEREYGSCSHHY
Site 80Y1102YGSCSHHYQQLLQSL
Site 81S1117EQGAQEESRCQRCIS
Site 82S1124SRCQRCISELKDIRL
Site 83T1138LQLEACETRTVHRLR
Site 84S1181GKGVARLSAEAEKVL
Site 85T1199EPSPAAPTLRSELEL
Site 86T1207LRSELELTLGKLEQV
Site 87S1216GKLEQVRSLSAIYLE
Site 88T1265TLPELEATKASLKKL
Site 89Y1348QLGRQLRYYRESADP
Site 90Y1349LGRQLRYYRESADPL
Site 91S1352QLRYYRESADPLGAW
Site 92S1378QAMPLADSQAVREQL
Site 93Y1412CQRFAKQYINAIKDY
Site 94Y1419YINAIKDYELQLVTY
Site 95Y1426YELQLVTYKAQLEPV
Site 96S1435AQLEPVASPAKKPKV
Site 97S1444AKKPKVQSGSESVIQ
Site 98S1446KPKVQSGSESVIQEY
Site 99S1448KVQSGSESVIQEYVD
Site 100Y1453SESVIQEYVDLRTHY
Site 101T1458QEYVDLRTHYSELTT
Site 102Y1460YVDLRTHYSELTTLT
Site 103S1461VDLRTHYSELTTLTS
Site 104T1464RTHYSELTTLTSQYI
Site 105T1465THYSELTTLTSQYIK
Site 106S1468SELTTLTSQYIKFIS
Site 107S1475SQYIKFISETLRRME
Site 108T1477YIKFISETLRRMEEE
Site 109S1554DAQQQKRSIQEELQQ
Site 110S1565ELQQLRQSSEAEIQA
Site 111S1566LQQLRQSSEAEIQAK
Site 112T1601VRLQLEATERQRGGA
Site 113S1644RRQVQDESQRKRQAE
Site 114S1717SAEAELQSKRASFAE
Site 115S1721ELQSKRASFAEKTAQ
Site 116S1732KTAQLERSLQEEHVA
Site 117S1793EEVAQQKSLAQAEAE
Site 118T1859LIRLRAETEQGEQQR
Site 119S1907EMEVLLASKARAEEE
Site 120S1915KARAEEESRSTSEKS
Site 121S1917RAEEESRSTSEKSKQ
Site 122T1918AEEESRSTSEKSKQR
Site 123S1919EEESRSTSEKSKQRL
Site 124S1922SRSTSEKSKQRLEAE
Site 125T1983LAAIGEATRLKTEAE
Site 126T1987GEATRLKTEAEIALK
Site 127S2039LAQLRKASDSELERQ
Site 128S2041QLRKASDSELERQKG
Site 129T2053QKGLVEDTLRQRRQV
Site 130S2090LELGRIRSNAEDTLR
Site 131T2095IRSNAEDTLRSKEQA
Site 132S2130AEERVQKSLAAEEEA
Site 133S2169RERAEQESARQLQLA
Site 134T2205KEQELQQTLQQEQSV
Site 135S2211QTLQQEQSVLDQLRG
Site 136S2244AEREAAQSRRQVEEA
Site 137T2314HKKFAEQTLRQKAQV
Site 138T2326AQVEQELTTLRLQLE
Site 139T2354QRLKAEATEAARQRS
Site 140S2361TEAARQRSQVEEELF
Site 141S2369QVEEELFSVRVQMEE
Site 142T2399ILRDKDNTQRFLQEE
Site 143S2421AEEAARLSVAAQEAA
Site 144S2516RQRQLEMSAEAERLK
Site 145S2530KLRVAEMSRAQARAE
Site 146T2561LHRTELATQEKVTLV
Site 147S2578LEIQRQQSDHDAERL
Site 148S2610AKLLQLKSEEMQTVQ
Site 149T2615LKSEEMQTVQQEQLL
Site 150S2631ETQALQQSFLSEKDS
Site 151S2634ALQQSFLSEKDSLLQ
Site 152S2638SFLSEKDSLLQRERF
Site 153S2688ERQRLVASMEEARRR
Site 154S2755HSEEVTASQVAATKT
Site 155T2762SQVAATKTLPNGRDA
Site 156S2782AEAEPEHSFDGLRRK
Site 157S2791DGLRRKVSAQRLQEA
Site 158S2802LQEAGILSAEELQRL
Site 159T2814QRLAQGHTTVDELAR
Site 160T2815RLAQGHTTVDELARR
Site 161Y2828RREDVRHYLQGRSSI
Site 162S2848KATNEKLSVYAALQR
Site 163T2886PVRNRRLTVNEAVKE
Site 164T2912LSAERAVTGYKDPYT
Site 165Y2914AERAVTGYKDPYTGQ
Site 166Y2918VTGYKDPYTGQQISL
Site 167T2919TGYKDPYTGQQISLF
Site 168S2924PYTGQQISLFQAMQK
Site 169T2949LLEAQIATGGVIDPV
Site 170Y2967RVPVDVAYRRGYFDE
Site 171Y2971DVAYRRGYFDEEMNR
Site 172S2984NRVLADPSDDTKGFF
Site 173T2987LADPSDDTKGFFDPN
Site 174T2995KGFFDPNTHENLTYL
Site 175Y3001NTHENLTYLQLLERC
Site 176Y3033AKGGELVYTDSEARD
Site 177T3034KGGELVYTDSEARDV
Site 178S3036GELVYTDSEARDVFE
Site 179T3046RDVFEKATVSAPFGK
Site 180Y3069WEIINSEYFTAEQRR
Site 181T3084DLLRQFRTGRITVEK
Site 182T3088QFRTGRITVEKIIKI
Site 183S3126PAAELLESRVIDREL
Site 184Y3134RVIDRELYQQLQRGE
Site 185S3143QLQRGERSVRDVAEV
Site 186T3152RDVAEVDTVRRALRG
Site 187S3176EEAGQKLSIYNALKK
Site 188Y3178AGQKLSIYNALKKDL
Site 189S3188LKKDLLPSDMAVALL
Site 190T3214PATSARLTVDEAVRA
Site 191S3234EFHEKLLSAEKAVTG
Site 192T3240LSAEKAVTGYRDPYT
Site 193Y3242AEKAVTGYRDPYTGQ
Site 194Y3246VTGYRDPYTGQSVSL
Site 195T3247TGYRDPYTGQSVSLF
Site 196S3250RDPYTGQSVSLFQAL
Site 197S3252PYTGQSVSLFQALKK
Site 198S3276RLLDAQLSTGGIVDP
Site 199T3277LLDAQLSTGGIVDPS
Site 200S3284TGGIVDPSKSHRVPL
Site 201S3286GIVDPSKSHRVPLDV
Site 202T3304RGCLDEETSRALSAP
Site 203S3305GCLDEETSRALSAPR
Site 204S3309EETSRALSAPRADAK
Site 205Y3318PRADAKAYSDPSTGE
Site 206S3319RADAKAYSDPSTGEP
Site 207T3323KAYSDPSTGEPATYG
Site 208Y3329STGEPATYGELQQRC
Site 209T3342RCRPDQLTGLSLLPL
Site 210S3345PDQLTGLSLLPLSEK
Site 211S3350GLSLLPLSEKAARAR
Site 212Y3362RARQEELYSELQARE
Site 213T3370SELQARETFEKTPVE
Site 214T3374ARETFEKTPVEVPVG
Site 215S3396TVWELISSEYFTAEQ
Site 216Y3398WELISSEYFTAEQRQ
Site 217T3400LISSEYFTAEQRQEL
Site 218T3417QFRTGKVTVEKVIKI
Site 219T3434TIVEEVETLRQERLS
Site 220S3441TLRQERLSFSGLRAP
Site 221S3457PASELLASGVLSRAQ
Site 222S3461LLASGVLSRAQFEQL
Site 223T3473EQLKDGKTTVKDLSE
Site 224S3479KTTVKDLSELGSVRT
Site 225S3483KDLSELGSVRTLLQG
Site 226T3486SELGSVRTLLQGSGC
Site 227S3491VRTLLQGSGCLAGIY
Site 228Y3498SGCLAGIYLEDTKEK
Site 229T3502AGIYLEDTKEKVSIY
Site 230S3507EDTKEKVSIYEAMRR
Site 231Y3509TKEKVSIYEAMRRGL
Site 232Y3545PVRNQRLYVHEAVKA
Site 233S3565ELHEQLLSAEKAVTG
Site 234T3571LSAEKAVTGYRDPYS
Site 235Y3573AEKAVTGYRDPYSGS
Site 236Y3577VTGYRDPYSGSTISL
Site 237S3578TGYRDPYSGSTISLF
Site 238S3583PYSGSTISLFQAMQK
Site 239Y3626RVPVDVAYQRGYFSE
Site 240Y3630DVAYQRGYFSEEMNR
Site 241T3654KGFFDPNTHENLTYR
Site 242T3659PNTHENLTYRQLLER
Site 243Y3660NTHENLTYRQLLERC
Site 244T3673RCVEDPETGLRLLPL
Site 245T3691EKAEVVETTQVYTEE
Site 246T3696VETTQVYTEEETRRA
Site 247T3707TRRAFEETQIDIPGG
Site 248S3716IDIPGGGSHGGSTMS
Site 249S3720GGGSHGGSTMSLWEV
Site 250T3721GGSHGGSTMSLWEVM
Site 251S3723SHGGSTMSLWEVMQS
Site 252S3730SLWEVMQSDLIPEEQ
Site 253T3751DFQAGRVTKERMIII
Site 254T3766IIEIIEKTEIIRQQG
Site 255S3776IRQQGLASYDYVRRR
Site 256Y3777RQQGLASYDYVRRRL
Site 257Y3779QGLASYDYVRRRLTA
Site 258T3785DYVRRRLTAEDLFEA
Site 259T3799ARIISLETYNLLREG
Site 260Y3800RIISLETYNLLREGT
Site 261T3807YNLLREGTRSLREAL
Site 262S3809LLREGTRSLREALEA
Site 263Y3822EAESAWCYLYGTGSV
Site 264Y3833TGSVAGVYLPGSRQT
Site 265T3840YLPGSRQTLSIYQAL
Site 266S3842PGSRQTLSIYQALKK
Site 267Y3844SRQTLSIYQALKKGL
Site 268T3880PVKGERLTVDEAVRK
Site 269S3900ELHDRLLSAERAVTG
Site 270T3906LSAERAVTGYRDPYT
Site 271Y3908AERAVTGYRDPYTEQ
Site 272Y3912VTGYRDPYTEQTISL
Site 273T3913TGYRDPYTEQTISLF
Site 274T3916RDPYTEQTISLFQAM
Site 275S3918PYTEQTISLFQAMKK
Site 276T3930MKKELIPTEEALRLL
Site 277Y3961HLPLEVAYQRGYLNK
Site 278Y3965EVAYQRGYLNKDTHD
Site 279T3970RGYLNKDTHDQLSEP
Site 280S3975KDTHDQLSEPSEVRS
Site 281S3978HDQLSEPSEVRSYVD
Site 282S3982SEPSEVRSYVDPSTD
Site 283Y3983EPSEVRSYVDPSTDE
Site 284S3987VRSYVDPSTDERLSY
Site 285T3988RSYVDPSTDERLSYT
Site 286S3993PSTDERLSYTQLLRR
Site 287Y3994STDERLSYTQLLRRC
Site 288T4007RCRRDDGTGQLLLPL
Site 289T4021LSDARKLTFRGLRKQ
Site 290T4030RGLRKQITMEELVRS
Site 291S4037TMEELVRSQVMDEAT
Site 292S4054QLREGLTSIEEVTKN
Site 293S4085DATKERLSVYQAMKK
Site 294Y4087TKERLSVYQAMKKGI
Site 295Y4112EAQAATGYVIDPIKG
Site 296S4143EFKDKLLSAERAVTG
Site 297T4149LSAERAVTGYKDPYS
Site 298Y4151AERAVTGYKDPYSGK
Site 299Y4155VTGYKDPYSGKLISL
Site 300S4156TGYKDPYSGKLISLF
Site 301S4161PYSGKLISLFQAMKK
Site 302S4195GIIDPEESHRLPVEV
Site 303Y4204RLPVEVAYKRGLFDE
Site 304S4221NEILTDPSDDTKGFF
Site 305T4224LTDPSDDTKGFFDPN
Site 306T4232KGFFDPNTEENLTYL
Site 307T4237PNTEENLTYLQLMER
Site 308Y4238NTEENLTYLQLMERC
Site 309T4247QLMERCITDPQTGLC
Site 310T4267EKKRERKTSSKSSVR
Site 311S4268KKRERKTSSKSSVRK
Site 312S4269KRERKTSSKSSVRKR
Site 313S4271ERKTSSKSSVRKRRV
Site 314S4272RKTSSKSSVRKRRVV
Site 315T4285VVIVDPETGKEMSVY
Site 316S4290PETGKEMSVYEAYRK
Site 317Y4292TGKEMSVYEAYRKGL
Site 318T4304KGLIDHQTYLELSEQ
Site 319Y4305GLIDHQTYLELSEQE
Site 320T4319ECEWEEITISSSDGV
Site 321S4321EWEEITISSSDGVVK
Site 322S4323EEITISSSDGVVKSM
Site 323S4329SSDGVVKSMIIDRRS
Site 324S4336SMIIDRRSGRQYDID
Site 325Y4340DRRSGRQYDIDDAIA
Site 326S4354AKNLIDRSALDQYRA
Site 327Y4359DRSALDQYRAGTLSI
Site 328T4363LDQYRAGTLSITEFA
Site 329S4365QYRAGTLSITEFADM
Site 330T4367RAGTLSITEFADMLS
Site 331S4374TEFADMLSGNAGGFR
Site 332S4382GNAGGFRSRSSSVGS
Site 333S4384AGGFRSRSSSVGSSS
Site 334S4385GGFRSRSSSVGSSSS
Site 335S4386GFRSRSSSVGSSSSY
Site 336S4389SRSSSVGSSSSYPIS
Site 337S4390RSSSVGSSSSYPISP
Site 338S4391SSSVGSSSSYPISPA
Site 339S4392SSVGSSSSYPISPAV
Site 340Y4393SVGSSSSYPISPAVS
Site 341S4396SSSSYPISPAVSRTQ
Site 342S4400YPISPAVSRTQLASW
Site 343T4402ISPAVSRTQLASWSD
Site 344S4406VSRTQLASWSDPTEE
Site 345S4408RTQLASWSDPTEETG
Site 346T4411LASWSDPTEETGPVA
Site 347T4444RNLVDNITGQRLLEA
Site 348S4462TGGIIDPSTGERFPV
Site 349T4463GGIIDPSTGERFPVT
Site 350T4470TGERFPVTDAVNKGL
Site 351T4501CGFEDPRTKTKMSAA
Site 352T4503FEDPRTKTKMSAAQA
Site 353Y4517ALKKGWLYYEAGQRF
Site 354Y4518LKKGWLYYEAGQRFL
Site 355T4539GGLIEPDTPGRVPLD
Site 356T4553DEALQRGTVDARTAQ
Site 357T4558RGTVDARTAQKLRDV
Site 358Y4568KLRDVGAYSKYLTCP
Site 359Y4571DVGAYSKYLTCPKTK
Site 360T4573GAYSKYLTCPKTKLK
Site 361T4577KYLTCPKTKLKISYK
Site 362S4590YKDALDRSMVEEGTG
Site 363Y4611AAQSTKGYYSPYSVS
Site 364Y4612AQSTKGYYSPYSVSG
Site 365S4613QSTKGYYSPYSVSGS
Site 366Y4615TKGYYSPYSVSGSGS
Site 367S4616KGYYSPYSVSGSGST
Site 368S4618YYSPYSVSGSGSTAG
Site 369S4620SPYSVSGSGSTAGSR
Site 370S4622YSVSGSGSTAGSRTG
Site 371T4623SVSGSGSTAGSRTGS
Site 372S4626GSGSTAGSRTGSRTG
Site 373T4628GSTAGSRTGSRTGSR
Site 374S4630TAGSRTGSRTGSRAG
Site 375T4632GSRTGSRTGSRAGSR
Site 376S4634RTGSRTGSRAGSRRG
Site 377S4638RTGSRAGSRRGSFDA
Site 378S4642RAGSRRGSFDATGSG
Site 379T4646RRGSFDATGSGFSMT
Site 380S4648GSFDATGSGFSMTFS
Site 381S4651DATGSGFSMTFSSSS
Site 382T4653TGSGFSMTFSSSSYS
Site 383S4655SGFSMTFSSSSYSSS
Site 384S4656GFSMTFSSSSYSSSG
Site 385S4657FSMTFSSSSYSSSGY
Site 386S4658SMTFSSSSYSSSGYG
Site 387Y4659MTFSSSSYSSSGYGR
Site 388S4660TFSSSSYSSSGYGRR
Site 389S4661FSSSSYSSSGYGRRY
Site 390S4662SSSSYSSSGYGRRYA
Site 391Y4664SSYSSSGYGRRYASG
Site 392Y4668SSGYGRRYASGSSAS
Site 393S4670GYGRRYASGSSASLG
Site 394S4672GRRYASGSSASLGGP
Site 395S4675YASGSSASLGGPESA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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