PhosphoNET

           
Protein Info 
   
Short Name:  PDCD1
Full Name:  Programmed cell death protein 1
Alias:  CD279; PD1; PD-1; Programmed cell death 1; SLEB2
Type:  Apoptosis
Mass (Da):  31647
Number AA:  288
UniProt ID:  Q15116
International Prot ID:  IPI00014830
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0004871     PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0006959  GO:0007275 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y121RRNDSGTYLCGAISL
Site 2S157EVPTAHPSPSPRPAG
Site 3S159PTAHPSPSPRPAGQF
Site 4T199CSRAARGTIGARRTG
Site 5T205GTIGARRTGQPLKED
Site 6S214QPLKEDPSAVPVFSV
Site 7T234DFQWREKTPEPPVPC
Site 8T259VFPSGMGTSSPARRG
Site 9S261PSGMGTSSPARRGSA
Site 10S267SSPARRGSADGPRSA
Site 11S273GSADGPRSAQPLRPE
Site 12S285RPEDGHCSWPL____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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