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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POSTN
Full Name:
Periostin
Alias:
OSF2; Osteoblast-specific factor 2; PDLPOSTN; Periodontal ligament-specific periostin; PN; SF-2
Type:
Adhesion
Mass (Da):
93314
Number AA:
836
UniProt ID:
Q15063
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0008201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0001501
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
P
I
N
A
N
N
H
Y
D
K
I
L
A
H
S
Site 2
Y56
I
L
G
T
K
K
K
Y
F
S
T
C
K
N
W
Site 3
Y77
G
Q
K
T
T
V
L
Y
E
C
C
P
G
Y
M
Site 4
Y83
L
Y
E
C
C
P
G
Y
M
R
M
E
G
M
K
Site 5
T113
G
I
V
G
A
T
T
T
Q
R
Y
S
D
A
S
Site 6
S117
A
T
T
T
Q
R
Y
S
D
A
S
K
L
R
E
Site 7
S120
T
Q
R
Y
S
D
A
S
K
L
R
E
E
I
E
Site 8
S131
E
E
I
E
G
K
G
S
F
T
Y
F
A
P
S
Site 9
Y134
E
G
K
G
S
F
T
Y
F
A
P
S
N
E
A
Site 10
S147
E
A
W
D
N
L
D
S
D
I
R
R
G
L
E
Site 11
S155
D
I
R
R
G
L
E
S
N
V
N
V
E
L
L
Site 12
T176
M
I
N
K
R
M
L
T
K
D
L
K
N
G
M
Site 13
Y189
G
M
I
I
P
S
M
Y
N
N
L
G
L
F
I
Site 14
S249
E
A
E
D
D
L
S
S
F
R
A
A
A
I
T
Site 15
T270
L
G
R
D
G
H
F
T
L
F
A
P
T
N
E
Site 16
Y303
A
S
E
A
L
M
K
Y
H
I
L
N
T
L
Q
Site 17
S337
E
I
G
C
D
G
D
S
I
T
V
N
G
I
K
Site 18
T353
V
N
K
K
D
I
V
T
N
N
G
V
I
H
L
Site 19
T383
L
A
G
K
Q
Q
T
T
F
T
D
L
V
A
Q
Site 20
Y403
A
L
R
P
D
G
E
Y
T
L
L
A
P
V
N
Site 21
S414
A
P
V
N
N
A
F
S
D
D
T
L
S
M
D
Site 22
T417
N
N
A
F
S
D
D
T
L
S
M
D
Q
R
L
Site 23
S419
A
F
S
D
D
T
L
S
M
D
Q
R
L
L
K
Site 24
Y444
K
V
G
L
N
E
L
Y
N
G
Q
I
L
E
T
Site 25
S498
I
I
K
P
A
E
K
S
L
H
E
K
L
K
Q
Site 26
S510
L
K
Q
D
K
R
F
S
T
F
L
S
L
L
E
Site 27
T511
K
Q
D
K
R
F
S
T
F
L
S
L
L
E
A
Site 28
T526
A
D
L
K
E
L
L
T
Q
P
G
D
W
T
L
Site 29
T532
L
T
Q
P
G
D
W
T
L
F
V
P
T
N
D
Site 30
T545
N
D
A
F
K
G
M
T
S
E
E
K
E
I
L
Site 31
S546
D
A
F
K
G
M
T
S
E
E
K
E
I
L
I
Site 32
T582
K
G
F
E
P
G
V
T
N
I
L
K
T
T
Q
Site 33
T587
G
V
T
N
I
L
K
T
T
Q
G
S
K
I
F
Site 34
T601
F
L
K
E
V
N
D
T
L
L
V
N
E
L
K
Site 35
T616
S
K
E
S
D
I
M
T
T
N
G
V
I
H
V
Site 36
T633
K
L
L
Y
P
A
D
T
P
V
G
N
D
Q
L
Site 37
S659
Q
I
K
F
V
R
G
S
T
F
K
E
I
P
V
Site 38
T660
I
K
F
V
R
G
S
T
F
K
E
I
P
V
T
Site 39
T667
T
F
K
E
I
P
V
T
V
Y
T
T
K
I
I
Site 40
T670
E
I
P
V
T
V
Y
T
T
K
I
I
T
K
V
Site 41
T675
V
Y
T
T
K
I
I
T
K
V
V
E
P
K
I
Site 42
T695
S
L
Q
P
I
I
K
T
E
G
P
T
L
T
K
Site 43
Y733
G
E
P
I
I
K
K
Y
T
K
I
I
D
G
V
Site 44
T756
T
R
E
E
R
I
I
T
G
P
E
I
K
Y
T
Site 45
Y762
I
T
G
P
E
I
K
Y
T
R
I
S
T
G
G
Site 46
T763
T
G
P
E
I
K
Y
T
R
I
S
T
G
G
G
Site 47
S766
E
I
K
Y
T
R
I
S
T
G
G
G
E
T
E
Site 48
T767
I
K
Y
T
R
I
S
T
G
G
G
E
T
E
E
Site 49
T775
G
G
G
E
T
E
E
T
L
K
K
L
L
Q
E
Site 50
T812
K
R
L
L
Q
G
D
T
P
V
R
K
L
Q
A
Site 51
S826
A
N
K
K
V
Q
G
S
R
R
R
L
R
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation