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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMD6
Full Name:
26S proteasome non-ATPase regulatory subunit 6
Alias:
26S proteasome regulatory subunit S10
Type:
Mass (Da):
45513
Number AA:
389
UniProt ID:
Q15008
International Prot ID:
IPI00014151
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000502
GO:0005829
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0006510
GO:0006511
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
Q
L
R
F
L
L
S
L
P
E
H
R
G
D
Site 2
Y54
D
N
N
M
A
P
Y
Y
E
A
L
C
K
S
L
Site 3
Y110
A
M
M
A
K
A
E
Y
L
C
R
I
G
D
K
Site 4
T122
G
D
K
E
G
A
L
T
A
F
R
K
T
Y
D
Site 5
Y128
L
T
A
F
R
K
T
Y
D
K
T
V
A
L
G
Site 6
T131
F
R
K
T
Y
D
K
T
V
A
L
G
H
R
L
Site 7
T161
N
D
L
I
T
R
N
T
E
K
A
K
S
L
I
Site 8
S166
R
N
T
E
K
A
K
S
L
I
E
E
G
G
D
Site 9
S210
D
T
V
S
T
F
T
S
Y
E
L
M
D
Y
K
Site 10
Y216
T
S
Y
E
L
M
D
Y
K
T
F
V
T
Y
T
Site 11
S262
A
V
R
Q
Y
L
F
S
L
Y
E
C
R
Y
S
Site 12
Y264
R
Q
Y
L
F
S
L
Y
E
C
R
Y
S
V
F
Site 13
Y292
D
W
L
F
A
P
H
Y
R
Y
Y
V
R
E
M
Site 14
Y294
L
F
A
P
H
Y
R
Y
Y
V
R
E
M
R
I
Site 15
Y295
F
A
P
H
Y
R
Y
Y
V
R
E
M
R
I
H
Site 16
Y304
R
E
M
R
I
H
A
Y
S
Q
L
L
E
S
Y
Site 17
S305
E
M
R
I
H
A
Y
S
Q
L
L
E
S
Y
R
Site 18
S310
A
Y
S
Q
L
L
E
S
Y
R
S
L
T
L
G
Site 19
S313
Q
L
L
E
S
Y
R
S
L
T
L
G
Y
M
A
Site 20
T315
L
E
S
Y
R
S
L
T
L
G
Y
M
A
E
A
Site 21
T356
K
V
N
E
I
V
E
T
N
R
P
D
S
K
N
Site 22
S361
V
E
T
N
R
P
D
S
K
N
W
Q
Y
Q
E
Site 23
Y366
P
D
S
K
N
W
Q
Y
Q
E
T
I
K
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation