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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT72
Full Name:
Keratin, type II cytoskeletal 72
Alias:
Cytokeratin-72;Keratin-72;Type II inner root sheath-specific keratin-K6irs2;Type-II keratin Kb35
Type:
Mass (Da):
55877
Number AA:
511
UniProt ID:
Q14CN4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
R
Q
L
T
H
F
P
R
G
E
R
Site 2
S17
R
G
E
R
L
G
F
S
G
C
S
A
V
L
S
Site 3
S30
L
S
G
G
I
G
S
S
S
A
S
F
R
A
R
Site 4
S31
S
G
G
I
G
S
S
S
A
S
F
R
A
R
V
Site 5
S33
G
I
G
S
S
S
A
S
F
R
A
R
V
K
G
Site 6
S41
F
R
A
R
V
K
G
S
A
S
F
G
S
K
S
Site 7
S43
A
R
V
K
G
S
A
S
F
G
S
K
S
L
S
Site 8
S46
K
G
S
A
S
F
G
S
K
S
L
S
C
L
G
Site 9
S48
S
A
S
F
G
S
K
S
L
S
C
L
G
G
S
Site 10
S50
S
F
G
S
K
S
L
S
C
L
G
G
S
R
S
Site 11
S61
G
S
R
S
L
A
L
S
A
A
A
R
R
G
G
Site 12
S138
A
L
N
N
K
F
A
S
F
I
D
K
V
R
F
Site 13
Y176
R
K
N
L
E
P
I
Y
E
G
Y
I
S
N
L
Site 14
S181
P
I
Y
E
G
Y
I
S
N
L
Q
K
Q
L
E
Site 15
S199
G
D
G
V
R
L
D
S
E
L
R
N
M
Q
D
Site 16
Y211
M
Q
D
L
V
E
D
Y
K
K
R
Y
E
V
E
Site 17
T223
E
V
E
I
N
R
R
T
A
A
E
N
E
F
V
Site 18
Y240
K
K
D
V
D
A
A
Y
M
N
K
V
E
L
Q
Site 19
S252
E
L
Q
A
K
V
D
S
L
T
D
E
I
K
F
Site 20
T254
Q
A
K
V
D
S
L
T
D
E
I
K
F
F
K
Site 21
T269
C
L
Y
E
G
E
I
T
Q
I
Q
S
H
I
S
Site 22
S273
G
E
I
T
Q
I
Q
S
H
I
S
D
T
S
I
Site 23
S276
T
Q
I
Q
S
H
I
S
D
T
S
I
V
L
S
Site 24
S279
Q
S
H
I
S
D
T
S
I
V
L
S
M
D
N
Site 25
S283
S
D
T
S
I
V
L
S
M
D
N
N
R
D
L
Site 26
S294
N
R
D
L
D
L
D
S
I
I
A
E
V
R
A
Site 27
Y303
I
A
E
V
R
A
Q
Y
E
E
I
A
L
K
S
Site 28
Y318
K
A
E
A
E
T
L
Y
Q
T
K
I
Q
E
L
Site 29
T328
K
I
Q
E
L
Q
V
T
A
G
Q
H
G
D
D
Site 30
T339
H
G
D
D
L
K
L
T
K
A
E
I
S
E
L
Site 31
S355
R
L
I
Q
R
I
R
S
E
I
G
N
V
K
K
Site 32
Y410
L
A
R
M
L
R
E
Y
Q
E
L
V
S
L
K
Site 33
S415
R
E
Y
Q
E
L
V
S
L
K
L
A
L
D
M
Site 34
T426
A
L
D
M
E
I
A
T
Y
R
K
L
L
E
S
Site 35
Y427
L
D
M
E
I
A
T
Y
R
K
L
L
E
S
E
Site 36
S433
T
Y
R
K
L
L
E
S
E
E
C
R
M
S
G
Site 37
S439
E
S
E
E
C
R
M
S
G
E
Y
P
N
S
V
Site 38
Y442
E
C
R
M
S
G
E
Y
P
N
S
V
S
I
S
Site 39
S447
G
E
Y
P
N
S
V
S
I
S
V
I
S
S
T
Site 40
S470
F
S
M
G
F
G
A
S
S
S
Y
S
Y
K
T
Site 41
S472
M
G
F
G
A
S
S
S
Y
S
Y
K
T
A
A
Site 42
S474
F
G
A
S
S
S
Y
S
Y
K
T
A
A
A
D
Site 43
T484
T
A
A
A
D
V
K
T
K
G
S
C
G
S
E
Site 44
T499
L
K
D
P
L
A
K
T
S
G
S
S
C
A
T
Site 45
S500
K
D
P
L
A
K
T
S
G
S
S
C
A
T
K
Site 46
S502
P
L
A
K
T
S
G
S
S
C
A
T
K
K
A
Site 47
T506
T
S
G
S
S
C
A
T
K
K
A
S
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation