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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC9A5
Full Name:
Sodium/hydrogen exchanger 5
Alias:
Na(+)/H(+) exchanger 5;Solute carrier family 9 member 5
Type:
Mass (Da):
99011
Number AA:
896
UniProt ID:
Q14940
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
A
G
A
A
E
E
P
T
Q
K
P
E
S
P
G
Site 2
S26
E
P
T
Q
K
P
E
S
P
G
E
P
P
P
G
Site 3
T71
F
H
L
S
R
K
V
T
S
L
V
P
E
S
C
Site 4
S72
H
L
S
R
K
V
T
S
L
V
P
E
S
C
L
Site 5
Y315
C
G
L
G
C
K
K
Y
V
E
A
N
I
S
H
Site 6
S321
K
Y
V
E
A
N
I
S
H
K
S
R
T
T
V
Site 7
S324
E
A
N
I
S
H
K
S
R
T
T
V
K
Y
T
Site 8
T327
I
S
H
K
S
R
T
T
V
K
Y
T
M
K
T
Site 9
Y330
K
S
R
T
T
V
K
Y
T
M
K
T
L
A
S
Site 10
S354
L
G
I
S
A
V
D
S
S
K
W
A
W
D
S
Site 11
S355
G
I
S
A
V
D
S
S
K
W
A
W
D
S
G
Site 12
S461
K
W
L
K
V
K
R
S
E
H
H
K
P
T
L
Site 13
T467
R
S
E
H
H
K
P
T
L
N
Q
E
L
H
E
Site 14
T476
N
Q
E
L
H
E
H
T
F
D
H
I
L
A
A
Site 15
Y507
W
E
Q
F
D
K
K
Y
L
S
Q
L
L
M
R
Site 16
S509
Q
F
D
K
K
Y
L
S
Q
L
L
M
R
R
S
Site 17
S516
S
Q
L
L
M
R
R
S
A
Y
R
I
R
D
Q
Site 18
Y518
L
L
M
R
R
S
A
Y
R
I
R
D
Q
I
W
Site 19
Y528
R
D
Q
I
W
D
V
Y
Y
R
L
N
I
R
D
Site 20
Y529
D
Q
I
W
D
V
Y
Y
R
L
N
I
R
D
A
Site 21
S538
L
N
I
R
D
A
I
S
F
V
D
Q
G
G
H
Site 22
S548
D
Q
G
G
H
V
L
S
S
T
G
L
T
L
P
Site 23
S549
Q
G
G
H
V
L
S
S
T
G
L
T
L
P
S
Site 24
S556
S
T
G
L
T
L
P
S
M
P
S
R
N
S
V
Site 25
S559
L
T
L
P
S
M
P
S
R
N
S
V
A
E
T
Site 26
S562
P
S
M
P
S
R
N
S
V
A
E
T
S
V
T
Site 27
T566
S
R
N
S
V
A
E
T
S
V
T
N
L
L
R
Site 28
S567
R
N
S
V
A
E
T
S
V
T
N
L
L
R
E
Site 29
T569
S
V
A
E
T
S
V
T
N
L
L
R
E
S
G
Site 30
S575
V
T
N
L
L
R
E
S
G
S
G
A
C
L
D
Site 31
S577
N
L
L
R
E
S
G
S
G
A
C
L
D
L
Q
Site 32
T588
L
D
L
Q
V
I
D
T
V
R
S
G
R
D
R
Site 33
S591
Q
V
I
D
T
V
R
S
G
R
D
R
E
D
A
Site 34
Y609
H
L
L
C
G
G
L
Y
K
P
R
R
R
Y
K
Site 35
Y615
L
Y
K
P
R
R
R
Y
K
A
S
C
S
R
H
Site 36
S618
P
R
R
R
Y
K
A
S
C
S
R
H
F
I
S
Site 37
S620
R
R
Y
K
A
S
C
S
R
H
F
I
S
E
D
Site 38
S647
N
M
K
R
R
L
E
S
F
K
S
T
K
H
N
Site 39
S650
R
R
L
E
S
F
K
S
T
K
H
N
I
C
F
Site 40
T651
R
L
E
S
F
K
S
T
K
H
N
I
C
F
T
Site 41
S660
H
N
I
C
F
T
K
S
K
P
R
P
R
K
T
Site 42
T667
S
K
P
R
P
R
K
T
G
R
R
K
K
D
G
Site 43
T681
G
V
A
N
A
E
A
T
N
G
K
H
R
G
L
Site 44
T699
D
T
A
A
V
I
L
T
V
E
S
E
E
E
E
Site 45
S702
A
V
I
L
T
V
E
S
E
E
E
E
E
E
S
Site 46
S709
S
E
E
E
E
E
E
S
D
S
S
E
T
E
K
Site 47
S711
E
E
E
E
E
S
D
S
S
E
T
E
K
E
D
Site 48
S712
E
E
E
E
S
D
S
S
E
T
E
K
E
D
D
Site 49
T714
E
E
S
D
S
S
E
T
E
K
E
D
D
E
G
Site 50
T729
I
I
F
V
A
R
A
T
S
E
V
L
Q
E
G
Site 51
S741
Q
E
G
K
V
S
G
S
L
E
V
C
P
S
P
Site 52
S747
G
S
L
E
V
C
P
S
P
R
I
I
P
P
S
Site 53
S754
S
P
R
I
I
P
P
S
P
T
C
A
E
K
E
Site 54
S766
E
K
E
L
P
W
K
S
G
Q
G
D
L
A
V
Site 55
Y774
G
Q
G
D
L
A
V
Y
V
S
S
E
T
T
K
Site 56
T789
I
V
P
V
D
M
Q
T
G
W
N
Q
S
I
S
Site 57
S794
M
Q
T
G
W
N
Q
S
I
S
S
L
E
S
L
Site 58
S796
T
G
W
N
Q
S
I
S
S
L
E
S
L
A
S
Site 59
S797
G
W
N
Q
S
I
S
S
L
E
S
L
A
S
P
Site 60
S800
Q
S
I
S
S
L
E
S
L
A
S
P
P
C
N
Site 61
S803
S
S
L
E
S
L
A
S
P
P
C
N
Q
A
P
Site 62
T813
C
N
Q
A
P
I
L
T
C
L
P
P
H
P
R
Site 63
T822
L
P
P
H
P
R
G
T
E
E
P
Q
V
P
L
Site 64
S833
Q
V
P
L
H
L
P
S
D
P
R
S
S
F
A
Site 65
S837
H
L
P
S
D
P
R
S
S
F
A
F
P
P
S
Site 66
S838
L
P
S
D
P
R
S
S
F
A
F
P
P
S
L
Site 67
S844
S
S
F
A
F
P
P
S
L
A
K
A
G
R
S
Site 68
S851
S
L
A
K
A
G
R
S
R
S
E
S
S
A
D
Site 69
S853
A
K
A
G
R
S
R
S
E
S
S
A
D
L
P
Site 70
S855
A
G
R
S
R
S
E
S
S
A
D
L
P
Q
Q
Site 71
T875
L
M
G
H
K
D
H
T
H
L
S
P
G
T
A
Site 72
S878
H
K
D
H
T
H
L
S
P
G
T
A
T
S
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation