PhosphoNET

           
Protein Info 
   
Short Name:  PTPRCAP
Full Name:  Protein tyrosine phosphatase receptor type C-associated protein
Alias:  CD45-AP; CD45-associated protein; LPAP; Lymphocyte phosphatase-associated phosphoprotein; Protein tyrosine phosphatase receptor type C-associated; Protein tyrosine phosphatase, receptor type, c polypeptide-associated; Protein tyrosine phosphatase, receptor type, C-associated; Protein tyrosine phosphatase, receptor type, C-associated protein; PTCA; PTPRC-associated
Type:  Cell surface
Mass (Da):  21196
Number AA:  206
UniProt ID:  Q14761
International Prot ID:  IPI00023786
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0006952     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T6__MALPCTLGLGMLL
Site 2S24GALGSGGSAEDSVGS
Site 3S28SGGSAEDSVGSSSVT
Site 4S58ALAWRRLSRDSGGYY
Site 5S61WRRLSRDSGGYYHPA
Site 6Y64LSRDSGGYYHPARLG
Site 7Y65SRDSGGYYHPARLGA
Site 8S85TRRLLWASPPGRWLQ
Site 9S99QARAELGSTDNDLER
Site 10T100ARAELGSTDNDLERQ
Site 11T113RQEDEQDTDYDHVAD
Site 12Y115EDEQDTDYDHVADGG
Site 13S139QQCGEASSPEQVPVR
Site 14S153RAEEARDSDTEGDLV
Site 15T155EEARDSDTEGDLVLG
Site 16S163EGDLVLGSPGPASAG
Site 17S168LGSPGPASAGGSAEA
Site 18S172GPASAGGSAEALLSD
Site 19S192GSAAWDDSARAAGGQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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