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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLINT1
Full Name:
Clathrin interactor 1
Alias:
Clathrin interacting protein localized in the trans-Golgi region; Clathrin-interacting protein localized in the trans-Golgi region; Clint; ENTH; Enthoprotin; EPN4; EPNR; Epsin 4; Epsin-4; EpsinR; Epsin-related protein; KIAA0171; SCZD1
Type:
Adaptor/scaffold
Mass (Da):
68259
Number AA:
625
UniProt ID:
Q14677
International Prot ID:
IPI00291930
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0030136
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0008289
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
GO:0006892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
R
E
L
V
D
K
A
T
N
V
V
M
N
Y
S
Site 2
S22
T
N
V
V
M
N
Y
S
E
I
E
S
K
V
R
Site 3
S26
M
N
Y
S
E
I
E
S
K
V
R
E
A
T
N
Site 4
T32
E
S
K
V
R
E
A
T
N
D
D
P
W
G
P
Site 5
Y80
K
K
N
W
R
R
V
Y
K
S
L
L
L
L
A
Site 6
S82
N
W
R
R
V
Y
K
S
L
L
L
L
A
Y
L
Site 7
S94
A
Y
L
I
R
N
G
S
E
R
V
V
T
S
A
Site 8
T99
N
G
S
E
R
V
V
T
S
A
R
E
H
I
Y
Site 9
S100
G
S
E
R
V
V
T
S
A
R
E
H
I
Y
D
Site 10
Y106
T
S
A
R
E
H
I
Y
D
L
R
S
L
E
N
Site 11
Y114
D
L
R
S
L
E
N
Y
H
F
V
D
E
H
G
Site 12
Y159
A
K
K
N
K
D
K
Y
V
G
V
S
S
D
S
Site 13
S163
K
D
K
Y
V
G
V
S
S
D
S
V
G
G
F
Site 14
S164
D
K
Y
V
G
V
S
S
D
S
V
G
G
F
R
Site 15
S166
Y
V
G
V
S
S
D
S
V
G
G
F
R
Y
S
Site 16
Y172
D
S
V
G
G
F
R
Y
S
E
R
Y
D
P
E
Site 17
S173
S
V
G
G
F
R
Y
S
E
R
Y
D
P
E
P
Site 18
Y176
G
F
R
Y
S
E
R
Y
D
P
E
P
K
S
K
Site 19
S193
E
E
W
D
K
N
K
S
A
F
P
F
S
D
K
Site 20
S198
N
K
S
A
F
P
F
S
D
K
L
G
E
L
S
Site 21
S205
S
D
K
L
G
E
L
S
D
K
I
G
S
T
I
Site 22
T215
I
G
S
T
I
D
D
T
I
S
K
F
R
R
K
Site 23
S217
S
T
I
D
D
T
I
S
K
F
R
R
K
D
R
Site 24
S227
R
R
K
D
R
E
D
S
P
E
R
C
S
D
S
Site 25
S232
E
D
S
P
E
R
C
S
D
S
D
E
E
K
K
Site 26
S234
S
P
E
R
C
S
D
S
D
E
E
K
K
A
R
Site 27
S245
K
K
A
R
R
G
R
S
P
K
G
E
F
K
D
Site 28
T256
E
F
K
D
E
E
E
T
V
T
T
K
H
I
H
Site 29
T258
K
D
E
E
E
T
V
T
T
K
H
I
H
I
T
Site 30
T259
D
E
E
E
T
V
T
T
K
H
I
H
I
T
Q
Site 31
T272
T
Q
A
T
E
T
T
T
T
R
H
K
R
T
A
Site 32
T273
Q
A
T
E
T
T
T
T
R
H
K
R
T
A
N
Site 33
S282
H
K
R
T
A
N
P
S
K
T
I
D
L
G
A
Site 34
Y293
D
L
G
A
A
A
H
Y
T
G
D
K
A
S
P
Site 35
T294
L
G
A
A
A
H
Y
T
G
D
K
A
S
P
D
Site 36
S299
H
Y
T
G
D
K
A
S
P
D
Q
N
A
S
T
Site 37
S305
A
S
P
D
Q
N
A
S
T
H
T
P
Q
S
S
Site 38
T306
S
P
D
Q
N
A
S
T
H
T
P
Q
S
S
V
Site 39
T308
D
Q
N
A
S
T
H
T
P
Q
S
S
V
K
T
Site 40
S311
A
S
T
H
T
P
Q
S
S
V
K
T
S
V
P
Site 41
S312
S
T
H
T
P
Q
S
S
V
K
T
S
V
P
S
Site 42
T315
T
P
Q
S
S
V
K
T
S
V
P
S
S
K
S
Site 43
S316
P
Q
S
S
V
K
T
S
V
P
S
S
K
S
S
Site 44
S319
S
V
K
T
S
V
P
S
S
K
S
S
G
D
L
Site 45
S320
V
K
T
S
V
P
S
S
K
S
S
G
D
L
V
Site 46
S322
T
S
V
P
S
S
K
S
S
G
D
L
V
D
L
Site 47
S323
S
V
P
S
S
K
S
S
G
D
L
V
D
L
F
Site 48
T333
L
V
D
L
F
D
G
T
S
Q
S
T
G
G
S
Site 49
S334
V
D
L
F
D
G
T
S
Q
S
T
G
G
S
A
Site 50
S336
L
F
D
G
T
S
Q
S
T
G
G
S
A
D
L
Site 51
S340
T
S
Q
S
T
G
G
S
A
D
L
F
G
G
F
Site 52
S356
D
F
G
S
A
A
A
S
G
S
F
P
S
Q
V
Site 53
S361
A
A
S
G
S
F
P
S
Q
V
T
A
T
S
G
Site 54
S383
S
A
F
N
Q
A
P
S
G
P
V
A
S
S
G
Site 55
S389
P
S
G
P
V
A
S
S
G
E
F
F
G
S
A
Site 56
S395
S
S
G
E
F
F
G
S
A
S
Q
P
A
V
E
Site 57
S409
E
L
V
S
G
S
Q
S
A
L
G
P
P
P
A
Site 58
S418
L
G
P
P
P
A
A
S
N
S
S
D
L
F
D
Site 59
S420
P
P
P
A
A
S
N
S
S
D
L
F
D
L
M
Site 60
S421
P
P
A
A
S
N
S
S
D
L
F
D
L
M
G
Site 61
T433
L
M
G
S
S
Q
A
T
M
T
S
S
Q
S
M
Site 62
T435
G
S
S
Q
A
T
M
T
S
S
Q
S
M
N
F
Site 63
S436
S
S
Q
A
T
M
T
S
S
Q
S
M
N
F
S
Site 64
S437
S
Q
A
T
M
T
S
S
Q
S
M
N
F
S
M
Site 65
S439
A
T
M
T
S
S
Q
S
M
N
F
S
M
M
S
Site 66
S443
S
S
Q
S
M
N
F
S
M
M
S
T
N
T
V
Site 67
S457
V
G
L
G
L
P
M
S
R
S
Q
N
T
D
M
Site 68
S459
L
G
L
P
M
S
R
S
Q
N
T
D
M
V
Q
Site 69
S468
N
T
D
M
V
Q
K
S
V
S
K
T
L
P
S
Site 70
S470
D
M
V
Q
K
S
V
S
K
T
L
P
S
T
W
Site 71
T472
V
Q
K
S
V
S
K
T
L
P
S
T
W
S
D
Site 72
S475
S
V
S
K
T
L
P
S
T
W
S
D
P
S
V
Site 73
T476
V
S
K
T
L
P
S
T
W
S
D
P
S
V
N
Site 74
S478
K
T
L
P
S
T
W
S
D
P
S
V
N
I
S
Site 75
S481
P
S
T
W
S
D
P
S
V
N
I
S
L
D
N
Site 76
S485
S
D
P
S
V
N
I
S
L
D
N
L
L
P
G
Site 77
S496
L
L
P
G
M
Q
P
S
K
P
Q
Q
P
S
L
Site 78
S502
P
S
K
P
Q
Q
P
S
L
N
T
M
I
Q
Q
Site 79
T569
G
M
A
P
L
G
N
T
P
M
M
N
Q
S
M
Site 80
T609
N
I
A
M
T
S
G
T
V
Q
P
K
Q
D
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation