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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0100
Full Name:
UPF0378 protein KIAA0100
Alias:
BCOX; BCOX1; Breast cancer overexpressed gene 1; Cancer/testis antigen 101; CT101; DKFZp686M0843; K0100; MGC111488; MLAA-22
Type:
Mass (Da):
253700
Number AA:
UniProt ID:
Q14667
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008924
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0006099
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S74
E
I
D
N
L
W
I
S
S
K
L
L
S
H
D
Site 2
S79
W
I
S
S
K
L
L
S
H
D
L
P
H
Y
V
Site 3
T97
F
G
E
V
R
I
R
T
D
L
Q
K
V
S
D
Site 4
S103
R
T
D
L
Q
K
V
S
D
L
S
A
P
F
S
Site 5
S106
L
Q
K
V
S
D
L
S
A
P
F
S
Q
S
A
Site 6
S110
S
D
L
S
A
P
F
S
Q
S
A
G
V
D
Q
Site 7
S121
G
V
D
Q
K
E
L
S
F
S
P
S
L
L
K
Site 8
S123
D
Q
K
E
L
S
F
S
P
S
L
L
K
I
F
Site 9
S151
M
V
L
K
V
D
T
S
E
S
L
W
H
I
Q
Site 10
S153
L
K
V
D
T
S
E
S
L
W
H
I
Q
I
S
Site 11
S160
S
L
W
H
I
Q
I
S
R
S
R
F
L
L
D
Site 12
S162
W
H
I
Q
I
S
R
S
R
F
L
L
D
S
D
Site 13
S168
R
S
R
F
L
L
D
S
D
G
K
R
L
I
C
Site 14
S178
K
R
L
I
C
E
V
S
L
C
K
I
N
S
K
Site 15
S184
V
S
L
C
K
I
N
S
K
V
L
K
S
G
Q
Site 16
S189
I
N
S
K
V
L
K
S
G
Q
L
E
D
T
C
Site 17
T195
K
S
G
Q
L
E
D
T
C
L
V
E
L
S
L
Site 18
S238
L
H
E
G
L
F
Q
S
Q
L
L
C
Q
G
P
Site 19
S255
A
S
K
P
V
P
C
S
E
V
T
E
N
L
V
Site 20
S287
K
V
K
M
E
N
T
S
V
V
L
S
M
N
S
Site 21
S291
E
N
T
S
V
V
L
S
M
N
S
Q
K
R
H
Site 22
S294
S
V
V
L
S
M
N
S
Q
K
R
H
L
T
W
Site 23
T300
N
S
Q
K
R
H
L
T
W
T
L
K
L
L
Q
Site 24
T302
Q
K
R
H
L
T
W
T
L
K
L
L
Q
F
L
Site 25
Y310
L
K
L
L
Q
F
L
Y
H
R
D
E
D
Q
L
Site 26
S321
E
D
Q
L
P
L
R
S
F
T
A
N
S
D
M
Site 27
T323
Q
L
P
L
R
S
F
T
A
N
S
D
M
A
Q
Site 28
S332
N
S
D
M
A
Q
M
S
T
E
L
L
L
E
D
Site 29
S344
L
E
D
G
L
L
L
S
Q
S
R
Q
R
I
V
Site 30
S399
L
A
L
E
T
Q
G
S
S
S
P
V
L
K
Q
Site 31
S401
L
E
T
Q
G
S
S
S
P
V
L
K
Q
R
K
Site 32
T411
L
K
Q
R
K
K
R
T
F
P
Q
I
L
A
P
Site 33
S446
P
F
A
L
G
F
N
S
I
S
L
D
Y
Q
H
Site 34
S448
A
L
G
F
N
S
I
S
L
D
Y
Q
H
L
R
Site 35
Y451
F
N
S
I
S
L
D
Y
Q
H
L
R
P
Q
S
Site 36
S458
Y
Q
H
L
R
P
Q
S
I
H
Q
R
G
V
L
Site 37
S476
H
L
C
W
R
V
G
S
D
S
H
I
Q
R
A
Site 38
S506
D
S
F
T
L
Q
G
S
Y
N
Q
P
L
G
L
Site 39
Y507
S
F
T
L
Q
G
S
Y
N
Q
P
L
G
L
S
Site 40
S514
Y
N
Q
P
L
G
L
S
S
T
Q
S
D
T
L
Site 41
S515
N
Q
P
L
G
L
S
S
T
Q
S
D
T
L
F
Site 42
T516
Q
P
L
G
L
S
S
T
Q
S
D
T
L
F
L
Site 43
S535
R
G
L
Q
V
E
A
S
D
T
C
A
Q
C
L
Site 44
T537
L
Q
V
E
A
S
D
T
C
A
Q
C
L
S
R
Site 45
S547
Q
C
L
S
R
I
L
S
L
M
G
P
Q
S
G
Site 46
S553
L
S
L
M
G
P
Q
S
G
K
S
A
V
S
R
Site 47
S556
M
G
P
Q
S
G
K
S
A
V
S
R
H
S
S
Site 48
S559
Q
S
G
K
S
A
V
S
R
H
S
S
F
G
E
Site 49
S562
K
S
A
V
S
R
H
S
S
F
G
E
S
V
S
Site 50
S563
S
A
V
S
R
H
S
S
F
G
E
S
V
S
L
Site 51
S567
R
H
S
S
F
G
E
S
V
S
L
L
W
K
V
Site 52
T639
C
K
A
P
D
I
P
T
P
V
L
S
L
S
M
Site 53
T650
S
L
S
M
L
S
I
T
Y
H
S
S
I
R
S
Site 54
S654
L
S
I
T
Y
H
S
S
I
R
S
L
E
V
Q
Site 55
S657
T
Y
H
S
S
I
R
S
L
E
V
Q
C
G
A
Site 56
Y679
P
P
D
H
M
Y
L
Y
Q
H
V
L
A
T
L
Site 57
S709
P
S
L
A
L
E
T
S
G
T
T
S
E
L
E
Site 58
T711
L
A
L
E
T
S
G
T
T
S
E
L
E
G
R
Site 59
S713
L
E
T
S
G
T
T
S
E
L
E
G
R
A
P
Site 60
T732
P
K
R
L
L
N
L
T
L
E
V
S
T
A
K
Site 61
S758
T
L
A
A
E
S
V
S
L
S
R
H
G
G
S
Site 62
S760
A
A
E
S
V
S
L
S
R
H
G
G
S
L
Q
Site 63
Y769
H
G
G
S
L
Q
A
Y
C
P
E
L
A
A
G
Site 64
S781
A
A
G
F
D
G
N
S
I
F
N
F
K
E
V
Site 65
T811
N
P
F
P
A
L
Q
T
L
R
N
R
V
W
L
Site 66
Y830
S
V
S
V
E
F
P
Y
Q
Y
D
F
S
R
T
Site 67
Y832
S
V
E
F
P
Y
Q
Y
D
F
S
R
T
L
D
Site 68
S860
Q
G
T
R
A
W
A
S
P
S
P
V
P
L
P
Site 69
S862
T
R
A
W
A
S
P
S
P
V
P
L
P
P
D
Site 70
Y894
E
V
K
L
H
D
N
Y
E
L
M
K
D
E
S
Site 71
S901
Y
E
L
M
K
D
E
S
K
E
S
A
K
R
L
Site 72
S904
M
K
D
E
S
K
E
S
A
K
R
L
Q
L
L
Site 73
Y935
A
R
K
I
E
E
L
Y
A
S
L
E
R
K
N
Site 74
S937
K
I
E
E
L
Y
A
S
L
E
R
K
N
I
E
Site 75
Y946
E
R
K
N
I
E
I
Y
I
Q
R
S
R
R
L
Site 76
Y954
I
Q
R
S
R
R
L
Y
G
N
T
P
M
R
R
Site 77
T957
S
R
R
L
Y
G
N
T
P
M
R
R
A
L
L
Site 78
S998
V
Q
E
L
D
P
G
S
P
F
P
P
E
G
L
Site 79
Y1032
R
I
R
D
Y
P
R
Y
L
F
E
I
R
D
W
Site 80
S1051
R
L
V
G
T
E
Q
S
G
Q
P
C
S
R
R
Site 81
S1056
E
Q
S
G
Q
P
C
S
R
R
R
Q
I
L
H
Site 82
Y1083
N
M
P
P
L
K
F
Y
H
D
F
H
S
E
I
Site 83
T1116
G
Q
C
V
D
L
L
T
K
P
S
A
D
P
S
Site 84
S1119
V
D
L
L
T
K
P
S
A
D
P
S
P
P
L
Site 85
S1123
T
K
P
S
A
D
P
S
P
P
L
P
W
W
D
Site 86
Y1158
Q
L
A
T
E
D
P
Y
N
T
T
E
N
M
H
Site 87
Y1196
N
V
R
T
A
S
K
Y
D
D
C
C
F
L
H
Site 88
S1226
G
N
P
H
D
H
H
S
V
T
L
R
A
P
E
Site 89
T1228
P
H
D
H
H
S
V
T
L
R
A
P
E
F
L
Site 90
S1246
P
L
G
Q
L
H
D
S
Y
R
A
F
R
S
E
Site 91
Y1247
L
G
Q
L
H
D
S
Y
R
A
F
R
S
E
N
Site 92
S1252
D
S
Y
R
A
F
R
S
E
N
L
N
L
S
I
Site 93
S1258
R
S
E
N
L
N
L
S
I
K
M
D
L
T
R
Site 94
T1264
L
S
I
K
M
D
L
T
R
H
S
G
T
I
S
Site 95
S1267
K
M
D
L
T
R
H
S
G
T
I
S
Q
P
R
Site 96
S1271
T
R
H
S
G
T
I
S
Q
P
R
I
L
L
Y
Site 97
Y1278
S
Q
P
R
I
L
L
Y
S
S
T
L
R
W
M
Site 98
S1279
Q
P
R
I
L
L
Y
S
S
T
L
R
W
M
Q
Site 99
S1280
P
R
I
L
L
Y
S
S
T
L
R
W
M
Q
N
Site 100
T1281
R
I
L
L
Y
S
S
T
L
R
W
M
Q
N
F
Site 101
S1311
L
F
N
N
L
K
P
S
K
K
K
L
G
Q
H
Site 102
S1323
G
Q
H
Y
K
Q
L
S
Y
T
A
L
F
P
Q
Site 103
Y1324
Q
H
Y
K
Q
L
S
Y
T
A
L
F
P
Q
L
Site 104
S1350
R
G
I
Q
I
E
C
S
Q
G
H
V
F
T
R
Site 105
T1359
G
H
V
F
T
R
G
T
Q
R
L
I
P
Q
A
Site 106
S1375
T
V
M
R
R
L
I
S
D
W
S
V
T
Q
M
Site 107
S1378
R
R
L
I
S
D
W
S
V
T
Q
M
V
S
D
Site 108
S1396
V
T
V
H
L
M
A
S
P
T
E
E
N
A
D
Site 109
T1398
V
H
L
M
A
S
P
T
E
E
N
A
D
H
C
Site 110
S1419
K
T
H
L
L
S
L
S
S
L
T
Y
Q
R
H
Site 111
S1420
T
H
L
L
S
L
S
S
L
T
Y
Q
R
H
S
Site 112
T1422
L
L
S
L
S
S
L
T
Y
Q
R
H
S
N
R
Site 113
Y1423
L
S
L
S
S
L
T
Y
Q
R
H
S
N
R
T
Site 114
S1427
S
L
T
Y
Q
R
H
S
N
R
T
A
E
E
E
Site 115
T1430
Y
Q
R
H
S
N
R
T
A
E
E
E
L
S
A
Site 116
S1436
R
T
A
E
E
E
L
S
A
R
D
G
D
P
T
Site 117
T1443
S
A
R
D
G
D
P
T
F
H
T
H
Q
L
H
Site 118
T1446
D
G
D
P
T
F
H
T
H
Q
L
H
L
V
D
Site 119
S1457
H
L
V
D
L
R
I
S
W
T
T
T
N
R
D
Site 120
T1460
D
L
R
I
S
W
T
T
T
N
R
D
I
A
F
Site 121
T1461
L
R
I
S
W
T
T
T
N
R
D
I
A
F
G
Site 122
Y1470
R
D
I
A
F
G
L
Y
D
G
Y
K
K
A
A
Site 123
S1484
A
V
L
K
R
N
L
S
T
E
A
L
K
G
L
Site 124
T1485
V
L
K
R
N
L
S
T
E
A
L
K
G
L
K
Site 125
S1509
P
K
R
G
V
P
T
S
A
S
A
P
P
R
V
Site 126
S1511
R
G
V
P
T
S
A
S
A
P
P
R
V
N
T
Site 127
T1518
S
A
P
P
R
V
N
T
P
S
F
S
G
Q
P
Site 128
S1520
P
P
R
V
N
T
P
S
F
S
G
Q
P
D
K
Site 129
S1522
R
V
N
T
P
S
F
S
G
Q
P
D
K
G
S
Site 130
S1529
S
G
Q
P
D
K
G
S
S
G
G
A
Y
M
L
Site 131
Y1534
K
G
S
S
G
G
A
Y
M
L
Q
K
L
I
E
Site 132
T1550
T
D
R
F
V
V
F
T
E
E
E
S
G
M
S
Site 133
S1557
T
E
E
E
S
G
M
S
D
Q
L
C
G
I
A
Site 134
Y1572
A
C
Q
T
D
D
I
Y
N
R
N
C
L
I
E
Site 135
S1624
D
T
L
K
Q
K
T
S
W
T
C
L
L
D
G
Site 136
Y1634
C
L
L
D
G
M
Q
Y
F
A
T
T
E
S
S
Site 137
T1637
D
G
M
Q
Y
F
A
T
T
E
S
S
P
T
E
Site 138
S1641
Y
F
A
T
T
E
S
S
P
T
E
Q
D
G
R
Site 139
T1643
A
T
T
E
S
S
P
T
E
Q
D
G
R
Q
L
Site 140
S1664
I
E
E
H
R
Q
R
S
L
D
S
V
Q
E
L
Site 141
S1667
H
R
Q
R
S
L
D
S
V
Q
E
L
M
E
S
Site 142
S1674
S
V
Q
E
L
M
E
S
G
Q
A
V
G
G
M
Site 143
T1686
G
G
M
V
T
T
T
T
D
W
N
Q
P
A
E
Site 144
T1752
K
Q
E
G
A
V
D
T
F
T
L
I
H
H
E
Site 145
T1754
E
G
A
V
D
T
F
T
L
I
H
H
E
L
E
Site 146
S1804
V
R
F
Q
L
E
I
S
S
N
P
E
E
Q
R
Site 147
S1805
R
F
Q
L
E
I
S
S
N
P
E
E
Q
R
S
Site 148
S1812
S
N
P
E
E
Q
R
S
S
I
L
H
L
Q
E
Site 149
S1813
N
P
E
E
Q
R
S
S
I
L
H
L
Q
E
A
Site 150
Y1836
R
Q
L
E
K
Q
M
Y
S
I
M
K
S
L
Q
Site 151
S1837
Q
L
E
K
Q
M
Y
S
I
M
K
S
L
Q
D
Site 152
S1841
Q
M
Y
S
I
M
K
S
L
Q
D
D
S
K
N
Site 153
S1846
M
K
S
L
Q
D
D
S
K
N
E
N
L
L
D
Site 154
S1904
R
K
Q
Q
E
D
V
S
V
V
R
R
T
E
F
Site 155
T1909
D
V
S
V
V
R
R
T
E
F
Y
F
A
Q
A
Site 156
Y1912
V
V
R
R
T
E
F
Y
F
A
Q
A
R
W
R
Site 157
T1921
A
Q
A
R
W
R
L
T
E
E
D
G
Q
L
G
Site 158
Y1939
L
E
L
Q
R
F
L
Y
S
K
V
N
K
S
D
Site 159
S1945
L
Y
S
K
V
N
K
S
D
D
T
A
E
H
L
Site 160
T1948
K
V
N
K
S
D
D
T
A
E
H
L
L
E
L
Site 161
S1977
K
V
V
L
R
P
Q
S
S
C
Q
S
G
R
Q
Site 162
S1978
V
V
L
R
P
Q
S
S
C
Q
S
G
R
Q
L
Site 163
S1981
R
P
Q
S
S
C
Q
S
G
R
Q
L
A
L
R
Site 164
S2001
R
P
P
V
G
G
I
S
V
K
E
H
F
E
V
Site 165
S2034
G
F
F
F
P
G
R
S
V
E
D
D
E
V
G
Site 166
S2047
V
G
D
E
E
D
K
S
K
L
V
T
T
G
I
Site 167
T2051
E
D
K
S
K
L
V
T
T
G
I
P
V
V
K
Site 168
T2065
K
P
R
Q
L
I
A
T
D
D
A
V
P
L
G
Site 169
T2082
K
G
V
A
Q
G
L
T
R
S
S
G
V
R
R
Site 170
S2084
V
A
Q
G
L
T
R
S
S
G
V
R
R
S
F
Site 171
S2085
A
Q
G
L
T
R
S
S
G
V
R
R
S
F
R
Site 172
S2090
R
S
S
G
V
R
R
S
F
R
K
S
P
E
H
Site 173
S2094
V
R
R
S
F
R
K
S
P
E
H
P
V
D
D
Site 174
S2135
S
Y
K
G
E
K
N
S
V
D
W
G
D
L
N
Site 175
S2168
A
M
A
V
K
R
D
S
R
K
A
L
V
A
Q
Site 176
S2185
K
E
K
L
R
L
K
S
A
T
G
S
E
V
R
Site 177
T2187
K
L
R
L
K
S
A
T
G
S
E
V
R
G
K
Site 178
S2189
R
L
K
S
A
T
G
S
E
V
R
G
K
L
E
Site 179
T2197
E
V
R
G
K
L
E
T
K
S
D
L
N
M
Q
Site 180
S2199
R
G
K
L
E
T
K
S
D
L
N
M
Q
Q
Q
Site 181
S2229
D
K
N
P
G
K
K
S
I
F
G
R
R
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation