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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF273
Full Name:
Zinc finger protein 273
Alias:
Zinc finger protein HZF9
Type:
Mass (Da):
64971
Number AA:
569
UniProt ID:
Q14593
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
S
A
P
R
G
P
P
Site 2
S3
_
_
_
_
_
M
S
S
A
P
R
G
P
P
S
Site 3
S10
S
A
P
R
G
P
P
S
V
A
P
L
P
A
G
Site 4
S21
L
P
A
G
I
G
R
S
T
A
K
T
P
G
L
Site 5
T22
P
A
G
I
G
R
S
T
A
K
T
P
G
L
P
Site 6
T25
I
G
R
S
T
A
K
T
P
G
L
P
G
S
L
Site 7
S31
K
T
P
G
L
P
G
S
L
E
M
G
P
L
T
Site 8
S47
R
D
V
A
I
E
F
S
L
E
E
W
Q
C
L
Site 9
Y62
D
T
S
Q
Q
N
L
Y
R
N
V
M
L
D
N
Site 10
Y70
R
N
V
M
L
D
N
Y
R
N
L
V
F
L
G
Site 11
S127
P
K
Q
G
L
K
D
S
F
Q
K
V
I
L
R
Site 12
Y136
Q
K
V
I
L
R
R
Y
G
K
Y
G
H
E
N
Site 13
Y139
I
L
R
R
Y
G
K
Y
G
H
E
N
L
Q
L
Site 14
S152
Q
L
R
K
G
C
K
S
A
D
E
H
K
V
H
Site 15
Y163
H
K
V
H
K
R
G
Y
N
G
L
N
Q
C
L
Site 16
T171
N
G
L
N
Q
C
L
T
T
T
Q
S
K
I
F
Site 17
T172
G
L
N
Q
C
L
T
T
T
Q
S
K
I
F
Q
Site 18
T173
L
N
Q
C
L
T
T
T
Q
S
K
I
F
Q
C
Site 19
S175
Q
C
L
T
T
T
Q
S
K
I
F
Q
C
D
K
Site 20
Y183
K
I
F
Q
C
D
K
Y
V
K
V
L
H
K
F
Site 21
S191
V
K
V
L
H
K
F
S
N
S
N
I
H
K
K
Site 22
T201
N
I
H
K
K
R
Q
T
G
K
K
P
F
K
C
Site 23
S219
G
K
S
C
C
I
L
S
Q
L
T
Q
H
K
K
Site 24
T227
Q
L
T
Q
H
K
K
T
A
T
R
V
N
F
Y
Site 25
Y234
T
A
T
R
V
N
F
Y
K
C
K
T
C
G
K
Site 26
S247
G
K
A
F
N
Q
F
S
N
L
T
K
H
K
I
Site 27
Y262
I
H
P
E
V
N
P
Y
K
C
E
E
C
G
K
Site 28
S274
C
G
K
A
F
N
Q
S
L
T
L
T
K
H
K
Site 29
T276
K
A
F
N
Q
S
L
T
L
T
K
H
K
K
I
Site 30
T278
F
N
Q
S
L
T
L
T
K
H
K
K
I
H
T
Site 31
Y290
I
H
T
E
E
K
P
Y
K
C
E
D
C
G
K
Site 32
Y318
I
H
T
G
T
K
P
Y
N
C
E
E
C
G
K
Site 33
S328
E
E
C
G
K
G
F
S
I
F
S
T
L
T
K
Site 34
S331
G
K
G
F
S
I
F
S
T
L
T
K
H
K
I
Site 35
Y346
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 36
S359
G
K
A
F
N
W
S
S
T
L
T
K
H
K
R
Site 37
T362
F
N
W
S
S
T
L
T
K
H
K
R
I
H
T
Site 38
T369
T
K
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 39
S386
C
G
K
A
F
N
Q
S
S
T
L
T
R
H
K
Site 40
S387
G
K
A
F
N
Q
S
S
T
L
T
R
H
K
I
Site 41
T388
K
A
F
N
Q
S
S
T
L
T
R
H
K
I
V
Site 42
T390
F
N
Q
S
S
T
L
T
R
H
K
I
V
H
T
Site 43
S414
C
G
K
A
F
K
R
S
T
T
L
T
K
H
K
Site 44
T415
G
K
A
F
K
R
S
T
T
L
T
K
H
K
R
Site 45
T416
K
A
F
K
R
S
T
T
L
T
K
H
K
R
I
Site 46
T418
F
K
R
S
T
T
L
T
K
H
K
R
I
Y
T
Site 47
Y424
L
T
K
H
K
R
I
Y
T
K
E
K
P
Y
K
Site 48
T425
T
K
H
K
R
I
Y
T
K
E
K
P
Y
K
C
Site 49
S440
E
E
C
G
K
A
F
S
V
F
S
T
L
T
K
Site 50
S471
G
S
A
F
R
A
F
S
T
L
T
E
H
K
R
Site 51
T481
T
E
H
K
R
V
H
T
G
E
K
P
Y
K
C
Site 52
Y486
V
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 53
S526
C
G
K
A
F
N
R
S
S
N
L
T
R
H
K
Site 54
S527
G
K
A
F
N
R
S
S
N
L
T
R
H
K
K
Site 55
T530
F
N
R
S
S
N
L
T
R
H
K
K
I
H
T
Site 56
T537
T
R
H
K
K
I
H
T
G
E
K
P
Y
K
P
Site 57
S549
Y
K
P
K
R
C
D
S
A
F
D
N
T
P
N
Site 58
T554
C
D
S
A
F
D
N
T
P
N
F
S
R
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation