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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF345
Full Name:
Zinc finger protein 345
Alias:
Zinc finger protein HZF10
Type:
Mass (Da):
55383
Number AA:
488
UniProt ID:
Q14585
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
E
N
L
T
K
H
S
I
E
C
S
Site 2
S8
M
E
N
L
T
K
H
S
I
E
C
S
S
F
R
Site 3
S12
T
K
H
S
I
E
C
S
S
F
R
G
D
W
E
Site 4
S30
Q
F
E
R
K
Q
G
S
Q
E
G
H
F
S
E
Site 5
S36
G
S
Q
E
G
H
F
S
E
M
I
F
T
P
E
Site 6
T41
H
F
S
E
M
I
F
T
P
E
D
M
P
T
F
Site 7
T47
F
T
P
E
D
M
P
T
F
S
I
Q
H
Q
R
Site 8
T57
I
Q
H
Q
R
I
H
T
D
E
K
L
L
E
C
Site 9
S75
G
K
D
F
S
F
V
S
V
L
V
R
H
Q
R
Site 10
T85
V
R
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 11
Y90
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 12
S101
E
C
G
K
A
F
G
S
G
A
N
L
A
Y
H
Site 13
Y107
G
S
G
A
N
L
A
Y
H
Q
R
I
H
T
G
Site 14
T113
A
Y
H
Q
R
I
H
T
G
E
K
P
F
E
C
Site 15
S129
E
C
G
K
A
F
G
S
G
S
N
L
T
H
H
Site 16
S131
G
K
A
F
G
S
G
S
N
L
T
H
H
Q
R
Site 17
T134
F
G
S
G
S
N
L
T
H
H
Q
R
I
H
T
Site 18
T141
T
H
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 19
S156
K
E
C
G
K
A
F
S
F
G
S
G
L
I
R
Site 20
Y174
I
H
S
G
E
K
P
Y
E
C
K
E
C
G
K
Site 21
S182
E
C
K
E
C
G
K
S
F
S
F
E
S
A
L
Site 22
S184
K
E
C
G
K
S
F
S
F
E
S
A
L
I
R
Site 23
S187
G
K
S
F
S
F
E
S
A
L
I
R
H
H
R
Site 24
T197
I
R
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 25
Y202
I
H
T
G
E
K
P
Y
E
C
I
D
C
G
K
Site 26
S215
G
K
A
F
G
S
G
S
N
L
T
Q
H
R
R
Site 27
T218
F
G
S
G
S
N
L
T
Q
H
R
R
I
H
T
Site 28
T225
T
Q
H
R
R
I
H
T
G
E
K
P
Y
E
C
Site 29
Y230
I
H
T
G
E
K
P
Y
E
C
K
A
C
G
M
Site 30
T253
T
R
H
Q
R
I
H
T
G
E
K
P
Y
I
C
Site 31
Y258
I
H
T
G
E
K
P
Y
I
C
N
E
C
G
K
Site 32
S268
N
E
C
G
K
A
F
S
F
G
S
A
L
T
R
Site 33
T281
T
R
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 34
Y286
I
H
T
G
E
K
P
Y
V
C
K
E
C
G
K
Site 35
S297
E
C
G
K
A
F
N
S
G
S
D
L
T
Q
H
Site 36
S299
G
K
A
F
N
S
G
S
D
L
T
Q
H
Q
R
Site 37
T302
F
N
S
G
S
D
L
T
Q
H
Q
R
I
H
T
Site 38
T309
T
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 39
Y314
I
H
T
G
E
K
P
Y
E
C
K
E
C
E
K
Site 40
S327
E
K
A
F
R
S
G
S
K
L
I
Q
H
Q
R
Site 41
T337
I
Q
H
Q
R
M
H
T
G
E
K
P
Y
E
C
Site 42
Y342
M
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 43
T350
E
C
K
E
C
G
K
T
F
S
S
G
S
D
L
Site 44
S353
E
C
G
K
T
F
S
S
G
S
D
L
T
Q
H
Site 45
S355
G
K
T
F
S
S
G
S
D
L
T
Q
H
H
R
Site 46
T358
F
S
S
G
S
D
L
T
Q
H
H
R
I
H
T
Site 47
T365
T
Q
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 48
S383
G
K
A
F
G
S
G
S
K
L
I
Q
H
Q
L
Site 49
Y398
I
H
T
G
E
R
P
Y
E
C
K
E
C
G
K
Site 50
S406
E
C
K
E
C
G
K
S
F
S
S
G
S
A
L
Site 51
S408
K
E
C
G
K
S
F
S
S
G
S
A
L
N
R
Site 52
S409
E
C
G
K
S
F
S
S
G
S
A
L
N
R
H
Site 53
S411
G
K
S
F
S
S
G
S
A
L
N
R
H
Q
R
Site 54
T421
N
R
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 55
Y436
K
E
C
G
K
A
F
Y
S
G
S
S
L
T
Q
Site 56
S437
E
C
G
K
A
F
Y
S
G
S
S
L
T
Q
H
Site 57
S439
G
K
A
F
Y
S
G
S
S
L
T
Q
H
Q
R
Site 58
T449
T
Q
H
Q
R
I
H
T
G
E
K
L
Y
E
C
Site 59
Y454
I
H
T
G
E
K
L
Y
E
C
K
N
C
G
K
Site 60
Y463
C
K
N
C
G
K
A
Y
G
R
D
S
E
F
Q
Site 61
S467
G
K
A
Y
G
R
D
S
E
F
Q
Q
H
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation