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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSC3
Full Name:
Desmocollin-3
Alias:
Cadherin family member 3; CDHF3; Desmocollin 3; Desmocollin-3; Desmocollin-4; DSC; DSC1; DSC2; DSC4; HT-CP
Type:
Adhesion protein
Mass (Da):
99969
Number AA:
896
UniProt ID:
Q14574
International Prot ID:
IPI00031549
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030057
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S67
S
A
D
L
I
R
S
S
D
P
D
F
R
V
L
Site 2
T81
L
N
D
G
S
V
Y
T
A
R
A
V
A
L
S
Site 3
S88
T
A
R
A
V
A
L
S
D
K
K
R
S
F
T
Site 4
S93
A
L
S
D
K
K
R
S
F
T
I
W
L
S
D
Site 5
T95
S
D
K
K
R
S
F
T
I
W
L
S
D
K
R
Site 6
S99
R
S
F
T
I
W
L
S
D
K
R
K
Q
T
Q
Site 7
T105
L
S
D
K
R
K
Q
T
Q
K
E
V
T
V
L
Site 8
T125
K
V
S
K
T
R
H
T
R
E
T
V
L
R
R
Site 9
T128
K
T
R
H
T
R
E
T
V
L
R
R
A
K
R
Site 10
S407
E
N
G
H
F
K
I
S
T
D
K
E
T
N
E
Site 11
T408
N
G
H
F
K
I
S
T
D
K
E
T
N
E
G
Site 12
T412
K
I
S
T
D
K
E
T
N
E
G
V
L
S
V
Site 13
S418
E
T
N
E
G
V
L
S
V
V
K
P
L
N
Y
Site 14
Y425
S
V
V
K
P
L
N
Y
E
E
N
R
Q
V
N
Site 15
Y493
V
G
S
K
I
N
G
Y
K
A
Y
D
P
E
N
Site 16
T737
Q
N
L
I
I
S
N
T
E
A
P
G
D
D
R
Site 17
S747
P
G
D
D
R
V
C
S
A
N
G
F
M
T
Q
Site 18
T755
A
N
G
F
M
T
Q
T
T
N
N
S
S
Q
G
Site 19
T756
N
G
F
M
T
Q
T
T
N
N
S
S
Q
G
F
Site 20
S759
M
T
Q
T
T
N
N
S
S
Q
G
F
C
G
T
Site 21
S791
G
G
N
Q
T
L
E
S
C
R
G
A
G
H
H
Site 22
T800
R
G
A
G
H
H
H
T
L
D
S
C
R
G
G
Site 23
Y816
T
E
V
D
N
C
R
Y
T
Y
S
E
W
H
S
Site 24
T817
E
V
D
N
C
R
Y
T
Y
S
E
W
H
S
F
Site 25
Y818
V
D
N
C
R
Y
T
Y
S
E
W
H
S
F
T
Site 26
S819
D
N
C
R
Y
T
Y
S
E
W
H
S
F
T
Q
Site 27
S823
Y
T
Y
S
E
W
H
S
F
T
Q
P
R
L
G
Site 28
T825
Y
S
E
W
H
S
F
T
Q
P
R
L
G
E
K
Site 29
S845
Q
N
E
D
R
M
P
S
Q
D
Y
V
L
T
Y
Site 30
Y848
D
R
M
P
S
Q
D
Y
V
L
T
Y
N
Y
E
Site 31
T851
P
S
Q
D
Y
V
L
T
Y
N
Y
E
G
R
G
Site 32
Y852
S
Q
D
Y
V
L
T
Y
N
Y
E
G
R
G
S
Site 33
Y854
D
Y
V
L
T
Y
N
Y
E
G
R
G
S
P
A
Site 34
S859
Y
N
Y
E
G
R
G
S
P
A
G
S
V
G
C
Site 35
S863
G
R
G
S
P
A
G
S
V
G
C
C
S
E
K
Site 36
S868
A
G
S
V
G
C
C
S
E
K
Q
E
E
D
G
Site 37
T888
N
L
E
P
K
F
I
T
L
A
E
A
C
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation