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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSP90AA2
Full Name:
Putative heat shock protein HSP 90-alpha A2
Alias:
Heat shock 90 kDa protein 1 alpha-like 3; Heat shock protein 86 kDa
Type:
Chaperone protein
Mass (Da):
39365
Number AA:
343
UniProt ID:
Q14568
International Prot ID:
IPI00031523
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0006950
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Site 2
T19
M
E
E
E
E
V
E
T
F
A
F
Q
A
E
I
Site 3
Y38
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
Site 4
S53
R
E
L
I
S
N
S
S
D
A
L
D
K
I
W
Site 5
Y61
D
A
L
D
K
I
W
Y
E
S
L
T
D
P
S
Site 6
S63
L
D
K
I
W
Y
E
S
L
T
D
P
S
K
L
Site 7
T65
K
I
W
Y
E
S
L
T
D
P
S
K
L
D
S
Site 8
S68
Y
E
S
L
T
D
P
S
K
L
D
S
G
K
E
Site 9
S72
T
D
P
S
K
L
D
S
G
K
E
L
H
I
N
Site 10
T88
I
P
N
K
Q
D
Q
T
L
T
I
V
D
T
G
Site 11
T90
N
K
Q
D
Q
T
L
T
I
V
D
T
G
I
G
Site 12
T94
Q
T
L
T
I
V
D
T
G
I
G
M
T
K
A
Site 13
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Site 14
T109
D
L
I
N
N
L
G
T
I
A
K
S
G
T
K
Site 15
S113
N
L
G
T
I
A
K
S
G
T
K
A
F
M
E
Site 16
Y160
K
H
N
D
D
E
Q
Y
A
W
E
S
S
A
G
Site 17
S164
D
E
Q
Y
A
W
E
S
S
A
G
G
S
F
T
Site 18
S169
W
E
S
S
A
G
G
S
F
T
V
R
T
D
T
Site 19
T171
S
S
A
G
G
S
F
T
V
R
T
D
T
G
E
Site 20
T174
G
G
S
F
T
V
R
T
D
T
G
E
R
M
G
Site 21
T176
S
F
T
V
R
T
D
T
G
E
R
M
G
R
G
Site 22
T184
G
E
R
M
G
R
G
T
K
V
I
L
H
L
K
Site 23
T195
L
H
L
K
E
D
Q
T
E
Y
L
E
E
Q
R
Site 24
Y197
L
K
E
D
Q
T
E
Y
L
E
E
Q
R
I
K
Site 25
S211
K
E
I
V
K
K
H
S
Q
L
I
G
Y
P
I
Site 26
S231
K
E
C
D
K
E
V
S
D
D
E
T
E
E
K
Site 27
T235
K
E
V
S
D
D
E
T
E
E
K
E
D
K
E
Site 28
S252
K
E
K
E
E
K
E
S
K
D
K
P
E
I
E
Site 29
S263
P
E
I
E
D
V
G
S
D
E
E
E
E
K
K
Site 30
Y283
K
K
K
T
K
E
K
Y
I
D
Q
E
E
L
N
Site 31
T292
D
Q
E
E
L
N
K
T
K
P
I
W
T
R
N
Site 32
T304
T
R
N
P
D
D
I
T
N
E
E
Y
G
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation