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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT33B
Full Name:
Keratin, type I cuticular Ha3-II
Alias:
Hair keratin, type I Ha3-II
Type:
Mass (Da):
46196
Number AA:
404
UniProt ID:
Q14525
International Prot ID:
IPI00872422
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
GO:0044422
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
N
F
C
L
P
S
L
S
C
R
T
S
C
S
S
Site 2
T14
L
P
S
L
S
C
R
T
S
C
S
S
R
P
C
Site 3
S15
P
S
L
S
C
R
T
S
C
S
S
R
P
C
V
Site 4
S17
L
S
C
R
T
S
C
S
S
R
P
C
V
P
P
Site 5
S18
S
C
R
T
S
C
S
S
R
P
C
V
P
P
S
Site 6
S25
S
R
P
C
V
P
P
S
C
H
G
Y
T
L
P
Site 7
Y29
V
P
P
S
C
H
G
Y
T
L
P
G
A
C
N
Site 8
S55
C
E
G
S
F
N
G
S
E
K
E
T
M
Q
F
Site 9
S69
F
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
Site 10
Y70
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
L
Site 11
S92
E
N
L
I
R
E
R
S
Q
Q
Q
E
P
L
L
Site 12
S102
Q
E
P
L
L
C
P
S
Y
Q
S
Y
F
K
T
Site 13
Y103
E
P
L
L
C
P
S
Y
Q
S
Y
F
K
T
I
Site 14
Y106
L
C
P
S
Y
Q
S
Y
F
K
T
I
E
E
L
Site 15
T109
S
Y
Q
S
Y
F
K
T
I
E
E
L
Q
Q
K
Site 16
S122
Q
K
I
L
C
S
K
S
E
N
A
R
L
V
V
Site 17
Y145
A
D
D
F
R
T
K
Y
Q
T
E
Q
S
L
R
Site 18
T147
D
F
R
T
K
Y
Q
T
E
Q
S
L
R
Q
L
Site 19
S150
T
K
Y
Q
T
E
Q
S
L
R
Q
L
V
E
S
Site 20
S157
S
L
R
Q
L
V
E
S
D
I
N
S
L
R
R
Site 21
S161
L
V
E
S
D
I
N
S
L
R
R
I
L
D
E
Site 22
T170
R
R
I
L
D
E
L
T
L
C
R
S
D
L
E
Site 23
S174
D
E
L
T
L
C
R
S
D
L
E
A
Q
M
E
Site 24
S189
S
L
K
E
E
L
L
S
L
K
Q
N
H
E
Q
Site 25
T200
N
H
E
Q
E
V
N
T
L
R
C
Q
L
G
D
Site 26
Y232
L
N
E
T
R
N
Q
Y
E
A
L
V
E
T
N
Site 27
S261
L
N
K
Q
V
V
S
S
S
E
Q
L
Q
S
Y
Site 28
S262
N
K
Q
V
V
S
S
S
E
Q
L
Q
S
Y
Q
Site 29
S267
S
S
S
E
Q
L
Q
S
Y
Q
A
E
I
I
E
Site 30
Y268
S
S
E
Q
L
Q
S
Y
Q
A
E
I
I
E
L
Site 31
T278
E
I
I
E
L
R
R
T
V
N
A
L
E
I
E
Site 32
S295
A
Q
H
N
L
R
Y
S
L
E
N
T
L
T
E
Site 33
T299
L
R
Y
S
L
E
N
T
L
T
E
S
E
A
R
Site 34
T301
Y
S
L
E
N
T
L
T
E
S
E
A
R
Y
S
Site 35
S303
L
E
N
T
L
T
E
S
E
A
R
Y
S
S
Q
Site 36
Y307
L
T
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Site 37
S308
T
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Q
Site 38
S309
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Q
S
Site 39
S312
A
R
Y
S
S
Q
L
S
Q
V
Q
S
L
I
T
Site 40
S316
S
Q
L
S
Q
V
Q
S
L
I
T
N
V
E
S
Site 41
T319
S
Q
V
Q
S
L
I
T
N
V
E
S
Q
L
A
Site 42
S323
S
L
I
T
N
V
E
S
Q
L
A
E
I
R
S
Site 43
S330
S
Q
L
A
E
I
R
S
D
L
E
R
Q
N
Q
Site 44
Y339
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
R
Site 45
T355
R
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
Site 46
Y356
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
E
Site 47
S358
C
E
I
N
T
Y
R
S
L
L
E
S
E
D
C
Site 48
S362
T
Y
R
S
L
L
E
S
E
D
C
K
L
P
S
Site 49
S369
S
E
D
C
K
L
P
S
N
P
C
A
T
T
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation