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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAT
Full Name:
Protocadherin Fat 1
Alias:
Cadherin-related tumor suppressor; CDHF7; FAT tumor suppressor 1; FATH; Protein fat homolog
Type:
Tumour suppressor protein
Mass (Da):
506278
Number AA:
4590
UniProt ID:
Q14517
International Prot ID:
IPI00031411
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009653
GO:0007267
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
F
Q
H
F
G
D
S
D
G
S
Q
R
L
E
Site 2
S150
N
D
L
R
P
L
F
S
P
T
S
Y
S
V
S
Site 3
T152
L
R
P
L
F
S
P
T
S
Y
S
V
S
L
P
Site 4
S153
R
P
L
F
S
P
T
S
Y
S
V
S
L
P
E
Site 5
T192
Y
Y
S
F
K
D
R
T
D
M
F
A
I
H
P
Site 6
Y212
V
L
T
G
R
L
D
Y
L
E
T
K
L
Y
E
Site 7
Y400
P
A
Y
S
H
L
R
Y
V
F
K
R
T
P
G
Site 8
T464
N
S
N
P
P
E
F
T
Q
T
A
Y
K
A
A
Site 9
Y468
P
E
F
T
Q
T
A
Y
K
A
A
F
D
E
N
Site 10
T771
C
F
M
I
D
M
E
T
G
M
L
K
I
L
S
Site 11
S778
T
G
M
L
K
I
L
S
P
L
D
R
E
T
T
Site 12
T1277
P
L
Y
R
V
I
A
T
D
K
D
E
G
P
N
Site 13
T1306
K
F
F
I
E
P
K
T
G
V
V
S
S
K
R
Site 14
S2621
K
G
T
S
V
V
K
S
A
S
D
A
D
E
G
Site 15
T3050
L
I
M
Q
I
S
A
T
D
A
D
I
R
S
N
Site 16
S3084
D
T
G
E
L
K
T
S
T
P
L
D
R
E
E
Site 17
T3404
T
K
L
L
D
R
E
T
I
S
G
Y
T
L
T
Site 18
S3406
L
L
D
R
E
T
I
S
G
Y
T
L
T
V
Q
Site 19
Y4234
T
A
F
L
Q
R
P
Y
F
D
S
K
L
N
K
Site 20
S4237
L
Q
R
P
Y
F
D
S
K
L
N
K
N
I
Y
Site 21
Y4244
S
K
L
N
K
N
I
Y
S
D
I
P
P
Q
V
Site 22
S4257
Q
V
P
V
R
P
I
S
Y
T
P
S
I
P
S
Site 23
Y4258
V
P
V
R
P
I
S
Y
T
P
S
I
P
S
D
Site 24
T4259
P
V
R
P
I
S
Y
T
P
S
I
P
S
D
S
Site 25
S4261
R
P
I
S
Y
T
P
S
I
P
S
D
S
R
N
Site 26
S4264
S
Y
T
P
S
I
P
S
D
S
R
N
N
L
D
Site 27
S4266
T
P
S
I
P
S
D
S
R
N
N
L
D
R
N
Site 28
S4274
R
N
N
L
D
R
N
S
F
E
G
S
A
I
P
Site 29
S4278
D
R
N
S
F
E
G
S
A
I
P
E
H
P
E
Site 30
T4288
P
E
H
P
E
F
S
T
F
N
P
E
S
V
H
Site 31
S4293
F
S
T
F
N
P
E
S
V
H
G
H
R
K
A
Site 32
S4316
N
L
P
P
P
P
P
S
N
S
P
S
D
S
D
Site 33
S4318
P
P
P
P
P
S
N
S
P
S
D
S
D
S
I
Site 34
S4320
P
P
P
S
N
S
P
S
D
S
D
S
I
Q
K
Site 35
S4322
P
S
N
S
P
S
D
S
D
S
I
Q
K
P
S
Site 36
S4324
N
S
P
S
D
S
D
S
I
Q
K
P
S
W
D
Site 37
Y4334
K
P
S
W
D
F
D
Y
D
T
K
V
V
D
L
Site 38
S4346
V
D
L
D
P
C
L
S
K
K
P
L
E
E
K
Site 39
S4355
K
P
L
E
E
K
P
S
Q
P
Y
S
A
R
E
Site 40
Y4358
E
E
K
P
S
Q
P
Y
S
A
R
E
S
L
S
Site 41
S4359
E
K
P
S
Q
P
Y
S
A
R
E
S
L
S
E
Site 42
S4363
Q
P
Y
S
A
R
E
S
L
S
E
V
Q
S
L
Site 43
S4365
Y
S
A
R
E
S
L
S
E
V
Q
S
L
S
S
Site 44
S4369
E
S
L
S
E
V
Q
S
L
S
S
F
Q
S
E
Site 45
S4371
L
S
E
V
Q
S
L
S
S
F
Q
S
E
S
C
Site 46
S4372
S
E
V
Q
S
L
S
S
F
Q
S
E
S
C
D
Site 47
S4375
Q
S
L
S
S
F
Q
S
E
S
C
D
D
N
G
Site 48
S4377
L
S
S
F
Q
S
E
S
C
D
D
N
G
Y
H
Site 49
S4393
D
T
S
D
W
M
P
S
V
P
L
P
D
I
Q
Site 50
Y4405
D
I
Q
E
F
P
N
Y
E
V
I
D
E
Q
T
Site 51
T4412
Y
E
V
I
D
E
Q
T
P
L
Y
S
A
D
P
Site 52
Y4415
I
D
E
Q
T
P
L
Y
S
A
D
P
N
A
I
Site 53
T4424
A
D
P
N
A
I
D
T
D
Y
Y
P
G
G
Y
Site 54
Y4426
P
N
A
I
D
T
D
Y
Y
P
G
G
Y
D
I
Site 55
Y4427
N
A
I
D
T
D
Y
Y
P
G
G
Y
D
I
E
Site 56
S4435
P
G
G
Y
D
I
E
S
D
F
P
P
P
P
E
Site 57
S4458
P
P
L
P
P
E
F
S
N
Q
F
E
S
I
H
Site 58
S4475
R
D
M
P
A
A
G
S
L
G
S
S
S
R
N
Site 59
S4478
P
A
A
G
S
L
G
S
S
S
R
N
R
Q
R
Site 60
S4479
A
A
G
S
L
G
S
S
S
R
N
R
Q
R
F
Site 61
S4480
A
G
S
L
G
S
S
S
R
N
R
Q
R
F
N
Site 62
Y4491
Q
R
F
N
L
N
Q
Y
L
P
N
F
Y
P
L
Site 63
Y4496
N
Q
Y
L
P
N
F
Y
P
L
D
M
S
E
P
Site 64
S4501
N
F
Y
P
L
D
M
S
E
P
Q
T
K
G
T
Site 65
T4505
L
D
M
S
E
P
Q
T
K
G
T
G
E
N
S
Site 66
S4512
T
K
G
T
G
E
N
S
T
C
R
E
P
H
A
Site 67
T4513
K
G
T
G
E
N
S
T
C
R
E
P
H
A
P
Site 68
Y4521
C
R
E
P
H
A
P
Y
P
P
G
Y
Q
R
H
Site 69
Y4525
H
A
P
Y
P
P
G
Y
Q
R
H
F
E
A
P
Site 70
Y4542
E
S
M
P
M
S
V
Y
A
S
T
A
S
C
S
Site 71
S4564
V
E
S
E
V
M
M
S
D
Y
E
S
G
D
D
Site 72
Y4566
S
E
V
M
M
S
D
Y
E
S
G
D
D
G
H
Site 73
S4568
V
M
M
S
D
Y
E
S
G
D
D
G
H
F
E
Site 74
T4578
D
G
H
F
E
E
V
T
I
P
P
L
D
S
Q
Site 75
S4584
V
T
I
P
P
L
D
S
Q
Q
H
T
E
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation