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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GAS6
Full Name:
Growth arrest-specific protein 6
Alias:
AXL receptor tyrosine kinase ligand; AXL stimulatory factor; AXLLG; AXSF; DKFZp666G247; FLJ34709; GAS-6; Growth arrest-specific 6; Growth-arrest-specific protein 6
Type:
Ligand, receptor tyrosine kinase
Mass (Da):
79680
Number AA:
UniProt ID:
Q14393
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0040008
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T39
L
L
P
A
R
E
A
T
Q
F
L
R
P
R
Q
Site 2
S71
E
C
V
E
E
L
C
S
R
E
E
A
R
E
V
Site 3
Y87
E
N
D
P
E
T
D
Y
F
Y
P
R
Y
L
D
Site 4
Y89
D
P
E
T
D
Y
F
Y
P
R
Y
L
D
C
I
Site 5
Y92
T
D
Y
F
Y
P
R
Y
L
D
C
I
N
K
Y
Site 6
Y99
Y
L
D
C
I
N
K
Y
G
S
P
Y
T
K
N
Site 7
S101
D
C
I
N
K
Y
G
S
P
Y
T
K
N
S
G
Site 8
Y103
I
N
K
Y
G
S
P
Y
T
K
N
S
G
F
A
Site 9
T111
T
K
N
S
G
F
A
T
C
V
Q
N
L
P
D
Site 10
T121
Q
N
L
P
D
Q
C
T
P
N
P
C
D
R
K
Site 11
S161
D
K
D
V
N
E
C
S
Q
E
N
G
G
C
L
Site 12
S181
K
P
G
S
F
H
C
S
C
H
S
G
F
E
L
Site 13
S184
S
F
H
C
S
C
H
S
G
F
E
L
S
S
D
Site 14
S189
C
H
S
G
F
E
L
S
S
D
G
R
T
C
Q
Site 15
S190
H
S
G
F
E
L
S
S
D
G
R
T
C
Q
D
Site 16
T194
E
L
S
S
D
G
R
T
C
Q
D
I
D
E
C
Site 17
S204
D
I
D
E
C
A
D
S
E
A
C
G
E
A
R
Site 18
S218
R
C
K
N
L
P
G
S
Y
S
C
L
C
D
E
Site 19
S220
K
N
L
P
G
S
Y
S
C
L
C
D
E
G
F
Site 20
Y229
L
C
D
E
G
F
A
Y
S
S
Q
E
K
A
C
Site 21
S231
D
E
G
F
A
Y
S
S
Q
E
K
A
C
R
D
Site 22
Y258
C
V
N
S
P
G
S
Y
T
C
H
C
D
G
R
Site 23
S271
G
R
G
G
L
K
L
S
Q
D
M
D
T
C
E
Site 24
T276
K
L
S
Q
D
M
D
T
C
E
L
E
A
G
W
Site 25
S293
P
R
H
R
R
D
G
S
P
A
A
R
P
G
R
Site 26
S305
P
G
R
G
A
Q
G
S
R
S
E
G
H
I
P
Site 27
S307
R
G
A
Q
G
S
R
S
E
G
H
I
P
D
R
Site 28
Y339
A
K
S
V
K
S
L
Y
L
G
R
M
F
S
G
Site 29
T411
Y
N
G
V
G
R
V
T
S
S
G
P
V
I
N
Site 30
S412
N
G
V
G
R
V
T
S
S
G
P
V
I
N
H
Site 31
S413
G
V
G
R
V
T
S
S
G
P
V
I
N
H
G
Site 32
Y460
F
Q
P
E
R
G
L
Y
H
L
N
L
T
V
G
Site 33
T499
N
W
L
N
G
E
D
T
T
I
Q
E
T
V
K
Site 34
T504
E
D
T
T
I
Q
E
T
V
K
V
N
T
R
M
Site 35
S515
N
T
R
M
Q
C
F
S
V
T
E
R
G
S
F
Site 36
T517
R
M
Q
C
F
S
V
T
E
R
G
S
F
Y
P
Site 37
S521
F
S
V
T
E
R
G
S
F
Y
P
G
S
G
F
Site 38
Y523
V
T
E
R
G
S
F
Y
P
G
S
G
F
A
F
Site 39
S526
R
G
S
F
Y
P
G
S
G
F
A
F
Y
S
L
Site 40
Y531
P
G
S
G
F
A
F
Y
S
L
D
Y
M
R
T
Site 41
S532
G
S
G
F
A
F
Y
S
L
D
Y
M
R
T
P
Site 42
T538
Y
S
L
D
Y
M
R
T
P
L
D
V
G
T
E
Site 43
Y585
L
S
V
A
L
V
D
Y
H
S
T
K
K
L
K
Site 44
S587
V
A
L
V
D
Y
H
S
T
K
K
L
K
K
Q
Site 45
T621
D
G
Q
E
H
V
V
T
V
S
L
R
D
G
E
Site 46
S623
Q
E
H
V
V
T
V
S
L
R
D
G
E
A
T
Site 47
T630
S
L
R
D
G
E
A
T
L
E
V
D
G
T
R
Site 48
T636
A
T
L
E
V
D
G
T
R
G
Q
S
E
V
S
Site 49
S640
V
D
G
T
R
G
Q
S
E
V
S
A
A
Q
L
Site 50
S660
V
L
E
R
H
L
R
S
P
V
L
T
F
A
G
Site 51
T664
H
L
R
S
P
V
L
T
F
A
G
G
L
P
D
Site 52
T675
G
L
P
D
V
P
V
T
S
A
P
V
T
A
F
Site 53
S676
L
P
D
V
P
V
T
S
A
P
V
T
A
F
Y
Site 54
T680
P
V
T
S
A
P
V
T
A
F
Y
R
G
C
M
Site 55
Y683
S
A
P
V
T
A
F
Y
R
G
C
M
T
L
E
Site 56
T688
A
F
Y
R
G
C
M
T
L
E
V
N
R
R
L
Site 57
T709
A
Y
K
H
S
D
I
T
A
H
S
C
P
P
V
Site 58
S712
H
S
D
I
T
A
H
S
C
P
P
V
E
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation