PhosphoNET

           
Protein Info 
   
Short Name:  FASTK
Full Name:  Fas-activated serine/threonine kinase
Alias:  EC 2.7.11.8; FAST; FAST kinase; kinase FASTK
Type:  EC 2.7.1.-; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.8; ATYPICAL group; FAST family
Mass (Da):  61104
Number AA:  549
UniProt ID:  Q14296
International Prot ID:  IPI00029714
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0033867  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0008624  GO:0006468 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T16GPRAPRPTEGATCAG
Site 2S27TCAGPGESWSPSPNS
Site 3S29AGPGESWSPSPNSML
Site 4S31PGESWSPSPNSMLRV
Site 5S34SWSPSPNSMLRVLLS
Site 6S78RPVGGGPSAGPVQGL
Site 7S94RLLEQAKSPGELLRW
Site 8S115KVRAHHYSVALRRLG
Site 9S127RLGQLLGSRPRPPPV
Site 10T138PPPVEQVTLQDLSQL
Site 11S211QGLEAALSCPRFLRY
Site 12Y218SCPRFLRYPRQHLIS
Site 13S225YPRQHLISSLAEARP
Site 14S226PRQHLISSLAEARPE
Site 15S273VVQETQLSSKVVQKL
Site 16Y289LPFGRLNYLPLEQQF
Site 17Y344FSPGFINYISGTPHA
Site 18Y357HALIVRRYLSLLDTA
Site 19Y372VELELPGYRGPRLPR
Site 20T392IFPQPLITDRARCKY
Site 21Y399TDRARCKYSHKDIVA
Site 22S400DRARCKYSHKDIVAE
Site 23Y418QLLGEEKYRQDLTVP
Site 24T423EKYRQDLTVPPGYCT
Site 25Y454TQDPFLPYPPRSCPQ
Site 26S458FLPYPPRSCPQGQAA
Site 27S497DGRVLLGSRALRERH
Site 28S522LPFEELESQRGLPQL
Site 29S531RGLPQLKSYLRQKLQ
Site 30Y532GLPQLKSYLRQKLQA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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