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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
E2F2
Full Name:
Transcription factor E2F2
Alias:
E2F-2
Type:
Mass (Da):
47506
Number AA:
437
UniProt ID:
Q14209
International Prot ID:
IPI00290548
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0003700
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0006355
GO:0006367
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
G
P
R
A
L
A
S
A
A
G
Q
T
P
K
Site 2
S23
P
K
V
V
P
A
M
S
P
T
E
L
W
P
S
Site 3
S30
S
P
T
E
L
W
P
S
G
L
S
S
P
Q
L
Site 4
T41
S
P
Q
L
C
P
A
T
A
T
Y
Y
T
P
L
Site 5
Y44
L
C
P
A
T
A
T
Y
Y
T
P
L
Y
P
Q
Site 6
T46
P
A
T
A
T
Y
Y
T
P
L
Y
P
Q
T
A
Site 7
Y49
A
T
Y
Y
T
P
L
Y
P
Q
T
A
P
P
A
Site 8
T52
Y
T
P
L
Y
P
Q
T
A
P
P
A
A
A
P
Site 9
T66
P
G
T
C
L
D
A
T
P
H
G
P
E
G
Q
Site 10
T104
P
V
V
P
E
F
P
T
P
K
G
K
C
I
R
Site 11
S117
I
R
V
D
G
L
P
S
P
K
T
P
K
S
P
Site 12
T120
D
G
L
P
S
P
K
T
P
K
S
P
G
E
K
Site 13
S123
P
S
P
K
T
P
K
S
P
G
E
K
T
R
Y
Site 14
T128
P
K
S
P
G
E
K
T
R
Y
D
T
S
L
G
Site 15
Y130
S
P
G
E
K
T
R
Y
D
T
S
L
G
L
L
Site 16
T132
G
E
K
T
R
Y
D
T
S
L
G
L
L
T
K
Site 17
S133
E
K
T
R
Y
D
T
S
L
G
L
L
T
K
K
Site 18
Y143
L
L
T
K
K
F
I
Y
L
L
S
E
S
E
D
Site 19
S146
K
K
F
I
Y
L
L
S
E
S
E
D
G
V
L
Site 20
Y170
D
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Site 21
T173
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Site 22
T202
R
G
M
F
E
D
P
T
R
P
G
K
Q
Q
Q
Site 23
T220
E
L
K
E
L
M
N
T
E
Q
A
L
D
Q
L
Site 24
S232
D
Q
L
I
Q
S
C
S
L
S
F
K
H
L
T
Site 25
S234
L
I
Q
S
C
S
L
S
F
K
H
L
T
E
D
Site 26
T239
S
L
S
F
K
H
L
T
E
D
K
A
N
K
R
Site 27
Y249
K
A
N
K
R
L
A
Y
V
T
Y
Q
D
I
R
Site 28
T251
N
K
R
L
A
Y
V
T
Y
Q
D
I
R
A
V
Site 29
Y252
K
R
L
A
Y
V
T
Y
Q
D
I
R
A
V
G
Site 30
T283
R
L
E
V
P
D
R
T
E
D
N
L
Q
I
Y
Site 31
Y290
T
E
D
N
L
Q
I
Y
L
K
S
T
Q
G
P
Site 32
T294
L
Q
I
Y
L
K
S
T
Q
G
P
I
E
V
Y
Site 33
Y301
T
Q
G
P
I
E
V
Y
L
C
P
E
E
V
Q
Site 34
S312
E
E
V
Q
E
P
D
S
P
S
E
E
P
L
P
Site 35
S314
V
Q
E
P
D
S
P
S
E
E
P
L
P
S
T
Site 36
S320
P
S
E
E
P
L
P
S
T
S
T
L
C
P
S
Site 37
T321
S
E
E
P
L
P
S
T
S
T
L
C
P
S
P
Site 38
S322
E
E
P
L
P
S
T
S
T
L
C
P
S
P
D
Site 39
T323
E
P
L
P
S
T
S
T
L
C
P
S
P
D
S
Site 40
S327
S
T
S
T
L
C
P
S
P
D
S
A
Q
P
S
Site 41
S330
T
L
C
P
S
P
D
S
A
Q
P
S
S
S
T
Site 42
S334
S
P
D
S
A
Q
P
S
S
S
T
D
P
S
I
Site 43
S335
P
D
S
A
Q
P
S
S
S
T
D
P
S
I
M
Site 44
S336
D
S
A
Q
P
S
S
S
T
D
P
S
I
M
E
Site 45
S340
P
S
S
S
T
D
P
S
I
M
E
P
T
A
S
Site 46
T345
D
P
S
I
M
E
P
T
A
S
S
V
P
A
P
Site 47
T355
S
V
P
A
P
A
P
T
P
Q
Q
A
P
P
P
Site 48
S364
Q
Q
A
P
P
P
P
S
L
V
P
L
E
A
T
Site 49
S373
V
P
L
E
A
T
D
S
L
L
E
L
P
H
P
Site 50
T385
P
H
P
L
L
Q
Q
T
E
D
Q
F
L
S
P
Site 51
S391
Q
T
E
D
Q
F
L
S
P
T
L
A
C
S
S
Site 52
T393
E
D
Q
F
L
S
P
T
L
A
C
S
S
P
L
Site 53
S404
S
S
P
L
I
S
F
S
P
S
L
D
Q
D
D
Site 54
S406
P
L
I
S
F
S
P
S
L
D
Q
D
D
Y
L
Site 55
Y412
P
S
L
D
Q
D
D
Y
L
W
G
L
E
A
G
Site 56
S423
L
E
A
G
E
G
I
S
D
L
F
D
S
Y
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation