KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DPYSL3
Full Name:
Dihydropyrimidinase-related protein 3
Alias:
Collapsin response mediator protein 4; CRMP4; Dihydropyrimidinase-like 3; DPYL3; DRP3; DRP-3; ULIP; Unc-33-like phosphoprotein 1
Type:
Axon guidance, neuronal growth cone collapse and cell migration protein
Mass (Da):
61963
Number AA:
570
UniProt ID:
Q14195
International Prot ID:
IPI00029111
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0030426
Uniprot
OncoNet
Molecular Function:
GO:0004157
PhosphoSite+
KinaseNET
Biological Process:
GO:0007399
GO:0006139
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
Y
Q
G
K
K
N
I
Site 2
T13
K
K
N
I
P
R
I
T
S
D
R
L
L
I
K
Site 3
S14
K
N
I
P
R
I
T
S
D
R
L
L
I
K
G
Site 4
S30
R
I
V
N
D
D
Q
S
F
Y
A
D
I
Y
M
Site 5
Y32
V
N
D
D
Q
S
F
Y
A
D
I
Y
M
E
D
Site 6
Y36
Q
S
F
Y
A
D
I
Y
M
E
D
G
L
I
K
Site 7
T74
P
G
G
I
D
V
H
T
H
F
Q
M
P
Y
K
Site 8
Y80
H
T
H
F
Q
M
P
Y
K
G
M
T
T
V
D
Site 9
T84
Q
M
P
Y
K
G
M
T
T
V
D
D
F
F
Q
Site 10
S115
V
V
P
E
P
E
S
S
L
T
E
A
Y
E
K
Site 11
T117
P
E
P
E
S
S
L
T
E
A
Y
E
K
W
R
Site 12
Y135
D
G
K
S
C
C
D
Y
A
L
H
V
D
I
T
Site 13
Y174
Y
M
A
Y
K
D
L
Y
Q
V
S
N
T
E
L
Site 14
S226
G
P
E
G
H
V
L
S
R
P
E
E
L
E
A
Site 15
Y251
S
Q
T
N
C
P
L
Y
V
T
K
V
M
S
K
Site 16
S259
V
T
K
V
M
S
K
S
A
A
D
L
I
S
Q
Site 17
S265
K
S
A
A
D
L
I
S
Q
A
R
K
K
G
N
Site 18
Y290
L
G
I
D
G
T
H
Y
W
S
K
N
W
A
K
Site 19
S304
K
A
A
A
F
V
T
S
P
P
L
S
P
D
P
Site 20
S308
F
V
T
S
P
P
L
S
P
D
P
T
T
P
D
Site 21
T312
P
P
L
S
P
D
P
T
T
P
D
Y
I
N
S
Site 22
T313
P
L
S
P
D
P
T
T
P
D
Y
I
N
S
L
Site 23
Y316
P
D
P
T
T
P
D
Y
I
N
S
L
L
A
S
Site 24
S319
T
T
P
D
Y
I
N
S
L
L
A
S
G
D
L
Site 25
S329
A
S
G
D
L
Q
L
S
G
S
A
H
C
T
F
Site 26
S331
G
D
L
Q
L
S
G
S
A
H
C
T
F
S
T
Site 27
T335
L
S
G
S
A
H
C
T
F
S
T
A
Q
K
A
Site 28
S337
G
S
A
H
C
T
F
S
T
A
Q
K
A
I
G
Site 29
T349
A
I
G
K
D
N
F
T
A
I
P
E
G
T
N
Site 30
S363
N
G
V
E
E
R
M
S
V
I
W
D
K
A
V
Site 31
Y395
A
A
K
I
F
N
L
Y
P
R
K
G
R
I
S
Site 32
S402
Y
P
R
K
G
R
I
S
V
G
S
D
S
D
L
Site 33
S405
K
G
R
I
S
V
G
S
D
S
D
L
V
I
W
Site 34
S407
R
I
S
V
G
S
D
S
D
L
V
I
W
D
P
Site 35
Y431
N
H
Q
S
A
A
E
Y
N
I
F
E
G
M
E
Site 36
S472
A
G
R
F
I
P
C
S
P
F
S
D
Y
V
Y
Site 37
Y477
P
C
S
P
F
S
D
Y
V
Y
K
R
I
K
A
Site 38
Y479
S
P
F
S
D
Y
V
Y
K
R
I
K
A
R
R
Site 39
Y499
H
A
V
P
R
G
M
Y
D
G
P
V
F
D
L
Site 40
T507
D
G
P
V
F
D
L
T
T
T
P
K
G
G
T
Site 41
T508
G
P
V
F
D
L
T
T
T
P
K
G
G
T
P
Site 42
T509
P
V
F
D
L
T
T
T
P
K
G
G
T
P
A
Site 43
T514
T
T
T
P
K
G
G
T
P
A
G
S
A
R
G
Site 44
S518
K
G
G
T
P
A
G
S
A
R
G
S
P
T
R
Site 45
S522
P
A
G
S
A
R
G
S
P
T
R
P
N
P
P
Site 46
T524
G
S
A
R
G
S
P
T
R
P
N
P
P
V
R
Site 47
S536
P
V
R
N
L
H
Q
S
G
F
S
L
S
G
T
Site 48
S539
N
L
H
Q
S
G
F
S
L
S
G
T
Q
V
D
Site 49
S541
H
Q
S
G
F
S
L
S
G
T
Q
V
D
E
G
Site 50
T543
S
G
F
S
L
S
G
T
Q
V
D
E
G
V
R
Site 51
S551
Q
V
D
E
G
V
R
S
A
S
K
R
I
V
A
Site 52
S553
D
E
G
V
R
S
A
S
K
R
I
V
A
P
P
Site 53
S564
V
A
P
P
G
G
R
S
N
I
T
S
L
S
_
Site 54
T567
P
G
G
R
S
N
I
T
S
L
S
_
_
_
_
Site 55
S568
G
G
R
S
N
I
T
S
L
S
_
_
_
_
_
Site 56
S570
R
S
N
I
T
S
L
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation