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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAFB2
Full Name:
Scaffold attachment factor B2
Alias:
KIAA0138; SFB2
Type:
RNA binding protein; Nuclear receptor co-regulator
Mass (Da):
107473
Number AA:
953
UniProt ID:
Q14151
International Prot ID:
IPI00005648
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
A
E
T
L
P
G
S
G
D
S
Site 2
S8
M
A
E
T
L
P
G
S
G
D
S
G
P
G
T
Site 3
S11
T
L
P
G
S
G
D
S
G
P
G
T
A
S
L
Site 4
T15
S
G
D
S
G
P
G
T
A
S
L
G
P
G
V
Site 5
S17
D
S
G
P
G
T
A
S
L
G
P
G
V
A
E
Site 6
T25
L
G
P
G
V
A
E
T
G
T
R
R
L
S
E
Site 7
T27
P
G
V
A
E
T
G
T
R
R
L
S
E
L
R
Site 8
S31
E
T
G
T
R
R
L
S
E
L
R
V
I
D
L
Site 9
T49
L
K
K
R
N
L
D
T
G
G
N
K
S
V
L
Site 10
S54
L
D
T
G
G
N
K
S
V
L
M
E
R
L
K
Site 11
T81
I
G
I
E
L
E
A
T
S
K
K
S
A
K
R
Site 12
S82
G
I
E
L
E
A
T
S
K
K
S
A
K
R
C
Site 13
S85
L
E
A
T
S
K
K
S
A
K
R
C
V
K
G
Site 14
T100
L
K
M
E
E
E
G
T
E
D
N
G
L
E
D
Site 15
S109
D
N
G
L
E
D
D
S
R
D
G
Q
E
D
M
Site 16
S119
G
Q
E
D
M
E
A
S
L
E
N
L
Q
N
M
Site 17
T137
D
M
S
V
L
D
E
T
E
V
A
N
S
S
A
Site 18
S142
D
E
T
E
V
A
N
S
S
A
P
D
F
G
E
Site 19
S143
E
T
E
V
A
N
S
S
A
P
D
F
G
E
D
Site 20
T152
P
D
F
G
E
D
G
T
D
G
L
L
D
S
F
Site 21
S158
G
T
D
G
L
L
D
S
F
C
D
S
K
E
Y
Site 22
S162
L
L
D
S
F
C
D
S
K
E
Y
V
A
A
Q
Site 23
Y165
S
F
C
D
S
K
E
Y
V
A
A
Q
L
R
Q
Site 24
T190
D
G
E
G
F
K
N
T
L
E
T
S
S
L
N
Site 25
T193
G
F
K
N
T
L
E
T
S
S
L
N
F
K
V
Site 26
S194
F
K
N
T
L
E
T
S
S
L
N
F
K
V
T
Site 27
S195
K
N
T
L
E
T
S
S
L
N
F
K
V
T
P
Site 28
T201
S
S
L
N
F
K
V
T
P
D
I
E
E
S
L
Site 29
S207
V
T
P
D
I
E
E
S
L
L
E
P
E
N
E
Site 30
S226
I
L
G
E
T
C
K
S
E
P
V
K
E
E
S
Site 31
S233
S
E
P
V
K
E
E
S
S
E
L
E
Q
P
F
Site 32
S234
E
P
V
K
E
E
S
S
E
L
E
Q
P
F
A
Site 33
T244
E
Q
P
F
A
Q
D
T
S
S
V
G
P
D
R
Site 34
S245
Q
P
F
A
Q
D
T
S
S
V
G
P
D
R
K
Site 35
S246
P
F
A
Q
D
T
S
S
V
G
P
D
R
K
L
Site 36
S262
E
E
E
D
L
F
D
S
A
H
P
E
E
G
D
Site 37
S274
E
G
D
L
D
L
A
S
E
S
T
A
H
A
Q
Site 38
S276
D
L
D
L
A
S
E
S
T
A
H
A
Q
S
S
Site 39
S283
S
T
A
H
A
Q
S
S
K
A
D
S
L
L
A
Site 40
S287
A
Q
S
S
K
A
D
S
L
L
A
V
V
K
R
Site 41
S321
E
P
A
V
E
Q
S
S
A
A
S
E
L
A
E
Site 42
S324
V
E
Q
S
S
A
A
S
E
L
A
E
A
S
S
Site 43
S330
A
S
E
L
A
E
A
S
S
E
E
L
A
E
A
Site 44
S331
S
E
L
A
E
A
S
S
E
E
L
A
E
A
P
Site 45
T339
E
E
L
A
E
A
P
T
E
A
P
S
P
E
A
Site 46
S343
E
A
P
T
E
A
P
S
P
E
A
R
D
S
K
Site 47
S349
P
S
P
E
A
R
D
S
K
E
D
G
R
K
F
Site 48
S383
G
A
D
Q
K
M
S
S
F
K
E
E
K
D
I
Site 49
S403
D
E
K
G
R
V
G
S
G
S
G
R
N
L
W
Site 50
S405
K
G
R
V
G
S
G
S
G
R
N
L
W
V
S
Site 51
S412
S
G
R
N
L
W
V
S
G
L
S
S
T
T
R
Site 52
S415
N
L
W
V
S
G
L
S
S
T
T
R
A
T
D
Site 53
T417
W
V
S
G
L
S
S
T
T
R
A
T
D
L
K
Site 54
T418
V
S
G
L
S
S
T
T
R
A
T
D
L
K
N
Site 55
T421
L
S
S
T
T
R
A
T
D
L
K
N
L
F
S
Site 56
S428
T
D
L
K
N
L
F
S
K
Y
G
K
V
V
G
Site 57
Y430
L
K
N
L
F
S
K
Y
G
K
V
V
G
A
K
Site 58
T440
V
V
G
A
K
V
V
T
N
A
R
S
P
G
A
Site 59
S444
K
V
V
T
N
A
R
S
P
G
A
R
C
Y
G
Site 60
Y450
R
S
P
G
A
R
C
Y
G
F
V
T
M
S
T
Site 61
T454
A
R
C
Y
G
F
V
T
M
S
T
S
D
E
A
Site 62
T462
M
S
T
S
D
E
A
T
K
C
I
S
H
L
H
Site 63
S479
E
L
H
G
R
M
I
S
V
E
K
A
K
N
E
Site 64
S493
E
P
A
G
K
K
L
S
D
R
K
E
C
E
V
Site 65
S506
E
V
K
K
E
K
L
S
S
V
D
R
H
H
S
Site 66
S507
V
K
K
E
K
L
S
S
V
D
R
H
H
S
V
Site 67
S513
S
S
V
D
R
H
H
S
V
E
I
K
I
E
K
Site 68
T521
V
E
I
K
I
E
K
T
V
I
K
K
E
E
K
Site 69
T555
D
E
L
K
P
G
P
T
N
R
S
R
V
T
K
Site 70
S558
K
P
G
P
T
N
R
S
R
V
T
K
S
G
S
Site 71
T561
P
T
N
R
S
R
V
T
K
S
G
S
R
G
M
Site 72
S563
N
R
S
R
V
T
K
S
G
S
R
G
M
E
R
Site 73
S565
S
R
V
T
K
S
G
S
R
G
M
E
R
T
V
Site 74
T571
G
S
R
G
M
E
R
T
V
V
M
D
K
S
K
Site 75
S577
R
T
V
V
M
D
K
S
K
G
E
P
V
I
S
Site 76
S584
S
K
G
E
P
V
I
S
V
K
T
T
S
R
S
Site 77
T587
E
P
V
I
S
V
K
T
T
S
R
S
K
E
R
Site 78
T588
P
V
I
S
V
K
T
T
S
R
S
K
E
R
S
Site 79
S589
V
I
S
V
K
T
T
S
R
S
K
E
R
S
S
Site 80
S591
S
V
K
T
T
S
R
S
K
E
R
S
S
K
S
Site 81
S595
T
S
R
S
K
E
R
S
S
K
S
Q
D
R
K
Site 82
S596
S
R
S
K
E
R
S
S
K
S
Q
D
R
K
S
Site 83
S598
S
K
E
R
S
S
K
S
Q
D
R
K
S
E
S
Site 84
S603
S
K
S
Q
D
R
K
S
E
S
K
E
K
R
D
Site 85
S613
K
E
K
R
D
I
L
S
F
D
K
I
K
E
Q
Site 86
T636
R
E
R
E
I
R
E
T
E
R
R
R
E
R
E
Site 87
Y721
R
Q
Q
E
Q
L
R
Y
E
Q
E
R
R
P
G
Site 88
Y732
R
R
P
G
R
R
P
Y
D
L
D
R
R
D
D
Site 89
Y741
L
D
R
R
D
D
A
Y
W
P
E
G
K
R
V
Site 90
Y754
R
V
A
M
E
D
R
Y
R
A
D
F
P
R
P
Site 91
Y776
D
H
R
D
R
G
Q
Y
Q
D
H
A
I
D
R
Site 92
S787
A
I
D
R
R
E
G
S
R
P
M
M
G
D
H
Site 93
Y800
D
H
R
D
G
Q
H
Y
G
D
D
R
H
G
H
Site 94
S818
P
E
R
H
G
R
D
S
R
D
G
W
G
G
Y
Site 95
Y825
S
R
D
G
W
G
G
Y
G
S
D
K
R
L
S
Site 96
S827
D
G
W
G
G
Y
G
S
D
K
R
L
S
E
G
Site 97
S832
Y
G
S
D
K
R
L
S
E
G
R
G
L
P
P
Site 98
S886
Q
G
G
E
R
G
L
S
G
P
S
G
P
G
H
Site 99
S896
S
G
P
G
H
M
A
S
R
G
G
V
A
G
R
Site 100
S912
G
F
A
Q
G
G
H
S
Q
G
H
V
V
P
G
Site 101
S929
L
E
G
G
G
V
A
S
Q
D
R
G
S
R
V
Site 102
S934
V
A
S
Q
D
R
G
S
R
V
P
H
P
H
P
Site 103
Y946
P
H
P
H
P
P
P
Y
P
H
F
T
R
R
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation