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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MORC3
Full Name:
MORC family CW-type zinc finger protein 3
Alias:
KIAA0136; MORC family CW-type zinc finger 3; Nuclear matrix protein NXP2; NXP2; ZCW5; ZCWCC3; Zinc finger CW-type coiled-coil domain protein 3; Zinc finger, CW-type with coiled-coil domain 3
Type:
RNA processing, RNA binding protein
Mass (Da):
107113
Number AA:
939
UniProt ID:
Q14149
International Prot ID:
IPI00937306
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016605
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007569
GO:0051457
GO:0048147
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
L
C
P
K
F
L
H
T
N
S
T
S
H
T
W
Site 2
T27
H
T
N
S
T
S
H
T
W
P
F
S
A
V
A
Site 3
Y41
A
E
L
I
D
N
A
Y
D
P
D
V
N
A
K
Site 4
S82
D
K
L
H
K
M
L
S
F
G
F
S
D
K
V
Site 5
S86
K
M
L
S
F
G
F
S
D
K
V
T
M
N
G
Site 6
Y100
G
H
V
P
V
G
L
Y
G
N
G
F
K
S
G
Site 7
S106
L
Y
G
N
G
F
K
S
G
S
M
R
L
G
K
Site 8
S108
G
N
G
F
K
S
G
S
M
R
L
G
K
D
A
Site 9
T119
G
K
D
A
I
V
F
T
K
N
G
E
S
M
S
Site 10
S126
T
K
N
G
E
S
M
S
V
G
L
L
S
Q
T
Site 11
T177
L
E
H
S
L
F
S
T
E
Q
K
L
L
A
E
Site 12
Y204
I
I
W
N
L
R
S
Y
K
N
A
T
E
F
D
Site 13
Y217
F
D
F
E
K
D
K
Y
D
I
R
I
P
E
D
Site 14
T229
P
E
D
L
D
E
I
T
G
K
K
G
Y
K
K
Site 15
S247
M
D
Q
I
A
P
E
S
D
Y
S
L
R
A
Y
Site 16
Y249
Q
I
A
P
E
S
D
Y
S
L
R
A
Y
C
S
Site 17
S250
I
A
P
E
S
D
Y
S
L
R
A
Y
C
S
I
Site 18
Y254
S
D
Y
S
L
R
A
Y
C
S
I
L
Y
L
K
Site 19
S256
Y
S
L
R
A
Y
C
S
I
L
Y
L
K
P
R
Site 20
Y259
R
A
Y
C
S
I
L
Y
L
K
P
R
M
Q
I
Site 21
T275
L
R
G
Q
K
V
K
T
Q
L
V
S
K
S
L
Site 22
S281
K
T
Q
L
V
S
K
S
L
A
Y
I
E
R
D
Site 23
Y290
A
Y
I
E
R
D
V
Y
R
P
K
F
L
S
K
Site 24
S296
V
Y
R
P
K
F
L
S
K
T
V
R
I
T
F
Site 25
T298
R
P
K
F
L
S
K
T
V
R
I
T
F
G
F
Site 26
T302
L
S
K
T
V
R
I
T
F
G
F
N
C
R
N
Site 27
Y313
N
C
R
N
K
D
H
Y
G
I
M
M
Y
H
R
Site 28
Y318
D
H
Y
G
I
M
M
Y
H
R
N
R
L
I
K
Site 29
Y327
R
N
R
L
I
K
A
Y
E
K
V
G
C
Q
L
Site 30
Y363
H
N
K
Q
D
F
D
Y
T
N
E
Y
R
L
T
Site 31
T370
Y
T
N
E
Y
R
L
T
I
T
A
L
G
E
K
Site 32
Y381
L
G
E
K
L
N
D
Y
W
N
E
M
K
V
K
Site 33
Y393
K
V
K
K
N
T
E
Y
P
L
N
L
P
V
E
Site 34
Y434
D
Q
L
P
E
K
W
Y
C
S
N
N
P
D
P
Site 35
Y462
E
D
L
V
H
P
T
Y
E
K
T
Y
K
K
T
Site 36
S497
L
F
R
P
T
A
L
S
T
P
S
F
S
S
P
Site 37
T498
S
L
K
R
R
L
S
T
R
S
S
I
L
N
A
Site 38
S500
P
T
A
L
S
T
P
S
F
S
S
P
K
E
S
Site 39
S502
N
A
K
N
R
R
L
S
S
Q
F
E
N
S
V
Site 40
S503
L
S
T
P
S
F
S
S
P
K
E
S
V
P
R
Site 41
S507
S
F
S
S
P
K
E
S
V
P
R
R
H
L
S
Site 42
S514
S
V
P
R
R
H
L
S
E
G
T
N
S
Y
A
Site 43
S519
H
L
S
E
G
T
N
S
Y
A
T
R
L
L
N
Site 44
S534
N
H
Q
V
P
P
Q
S
E
P
E
S
N
S
L
Site 45
S538
P
P
Q
S
E
P
E
S
N
S
L
K
R
R
L
Site 46
S540
Q
S
E
P
E
S
N
S
L
K
R
R
L
S
T
Site 47
S546
N
S
L
K
R
R
L
S
T
R
S
S
I
L
N
Site 48
T547
S
L
K
R
R
L
S
T
R
S
S
I
L
N
A
Site 49
S549
K
R
R
L
S
T
R
S
S
I
L
N
A
K
N
Site 50
S550
R
R
L
S
T
R
S
S
I
L
N
A
K
N
R
Site 51
S560
N
A
K
N
R
R
L
S
S
Q
F
E
N
S
V
Site 52
S561
A
K
N
R
R
L
S
S
Q
F
E
N
S
V
Y
Site 53
S566
L
S
S
Q
F
E
N
S
V
Y
K
G
D
D
D
Site 54
Y568
S
Q
F
E
N
S
V
Y
K
G
D
D
D
D
E
Site 55
T585
I
I
L
E
E
N
S
T
P
K
P
A
V
D
H
Site 56
S598
D
H
D
I
D
M
K
S
E
Q
S
H
V
E
Q
Site 57
S601
I
D
M
K
S
E
Q
S
H
V
E
Q
G
G
V
Site 58
S616
Q
V
E
F
V
G
D
S
E
P
C
G
Q
T
G
Site 59
T622
D
S
E
P
C
G
Q
T
G
S
T
S
T
S
S
Site 60
S624
E
P
C
G
Q
T
G
S
T
S
T
S
S
S
R
Site 61
T625
P
C
G
Q
T
G
S
T
S
T
S
S
S
R
C
Site 62
S626
C
G
Q
T
G
S
T
S
T
S
S
S
R
C
D
Site 63
S628
Q
T
G
S
T
S
T
S
S
S
R
C
D
Q
G
Site 64
S629
T
G
S
T
S
T
S
S
S
R
C
D
Q
G
N
Site 65
S630
G
S
T
S
T
S
S
S
R
C
D
Q
G
N
T
Site 66
T654
L
V
V
K
K
E
E
T
V
E
D
E
I
D
V
Site 67
T681
A
E
A
K
I
H
E
T
Q
E
T
T
D
K
S
Site 68
T684
K
I
H
E
T
Q
E
T
T
D
K
S
A
D
D
Site 69
S688
T
Q
E
T
T
D
K
S
A
D
D
A
G
C
Q
Site 70
Y713
V
T
E
E
K
E
N
Y
K
R
Q
C
H
M
F
Site 71
Y738
I
L
E
M
N
D
K
Y
V
K
K
E
T
C
H
Site 72
S758
D
A
V
F
L
L
E
S
I
N
G
K
S
E
S
Site 73
S763
L
E
S
I
N
G
K
S
E
S
P
D
H
M
V
Site 74
S765
S
L
K
R
R
L
S
T
R
S
S
I
L
N
A
Site 75
S771
N
A
K
N
R
R
L
S
S
Q
F
E
N
S
V
Site 76
S788
E
R
L
K
K
Q
C
S
A
L
Q
H
V
K
A
Site 77
S798
Q
H
V
K
A
E
C
S
Q
C
S
N
N
E
S
Site 78
S801
K
A
E
C
S
Q
C
S
N
N
E
S
K
S
E
Site 79
S805
S
Q
C
S
N
N
E
S
K
S
E
M
D
E
M
Site 80
S807
C
S
N
N
E
S
K
S
E
M
D
E
M
A
V
Site 81
S827
F
R
Q
L
D
K
C
S
I
E
R
D
Q
Y
K
Site 82
Y833
C
S
I
E
R
D
Q
Y
K
S
E
V
E
L
L
Site 83
S835
I
E
R
D
Q
Y
K
S
E
V
E
L
L
E
M
Site 84
S845
E
L
L
E
M
E
K
S
Q
I
R
S
Q
C
E
Site 85
S849
M
E
K
S
Q
I
R
S
Q
C
E
E
L
K
T
Site 86
T856
S
Q
C
E
E
L
K
T
E
V
E
Q
L
K
S
Site 87
S863
T
E
V
E
Q
L
K
S
T
N
Q
Q
T
A
T
Site 88
T870
S
T
N
Q
Q
T
A
T
D
V
S
T
S
S
N
Site 89
S876
A
T
D
V
S
T
S
S
N
I
E
E
S
V
N
Site 90
S881
T
S
S
N
I
E
E
S
V
N
H
M
D
G
E
Site 91
S889
V
N
H
M
D
G
E
S
L
K
L
R
S
L
R
Site 92
S894
G
E
S
L
K
L
R
S
L
R
V
N
V
G
Q
Site 93
Y917
L
D
L
Q
Q
V
N
Y
D
V
D
V
V
D
E
Site 94
S934
G
Q
V
V
E
Q
M
S
E
I
S
S
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation