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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DHX34
Full Name:
Probable ATP-dependent RNA helicase DHX34
Alias:
DEAH box protein 34
Type:
Mass (Da):
64567
Number AA:
576
UniProt ID:
Q14147
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
R
D
H
H
R
A
P
S
E
E
E
A
L
E
K
Site 2
Y49
A
F
F
R
E
E
D
Y
I
R
Q
G
S
E
E
Site 3
T75
Q
R
F
Q
N
L
K
T
S
R
K
E
E
K
D
Site 4
T99
A
L
A
D
L
P
R
T
Y
D
P
R
Y
R
I
Site 5
Y100
L
A
D
L
P
R
T
Y
D
P
R
Y
R
I
N
Site 6
Y104
P
R
T
Y
D
P
R
Y
R
I
N
L
S
V
L
Site 7
S109
P
R
Y
R
I
N
L
S
V
L
G
P
A
T
R
Site 8
S118
L
G
P
A
T
R
G
S
Q
G
L
G
R
H
L
Site 9
Y140
F
R
R
A
L
L
H
Y
L
D
F
G
Q
K
Q
Site 10
S192
G
D
T
G
C
G
K
S
T
Q
V
P
Q
Y
L
Site 11
T193
D
T
G
C
G
K
S
T
Q
V
P
Q
Y
L
L
Site 12
Y198
K
S
T
Q
V
P
Q
Y
L
L
A
A
G
F
S
Site 13
T210
G
F
S
H
V
A
C
T
Q
P
R
R
I
A
C
Site 14
S228
A
K
R
V
G
F
E
S
L
S
Q
Y
G
S
Q
Site 15
S230
R
V
G
F
E
S
L
S
Q
Y
G
S
Q
V
G
Site 16
Y232
G
F
E
S
L
S
Q
Y
G
S
Q
V
G
Y
Q
Site 17
S234
E
S
L
S
Q
Y
G
S
Q
V
G
Y
Q
I
R
Site 18
Y238
Q
Y
G
S
Q
V
G
Y
Q
I
R
F
E
S
T
Site 19
S244
G
Y
Q
I
R
F
E
S
T
R
S
A
A
T
K
Site 20
S269
R
Q
I
Q
R
E
P
S
L
P
Q
Y
E
V
L
Site 21
Y273
R
E
P
S
L
P
Q
Y
E
V
L
I
V
D
E
Site 22
S361
S
T
N
I
A
E
T
S
V
T
I
D
G
I
R
Site 23
S373
G
I
R
F
V
V
D
S
G
K
V
K
E
M
S
Site 24
S380
S
G
K
V
K
E
M
S
Y
D
P
Q
A
K
L
Site 25
S396
R
L
Q
E
F
W
I
S
Q
A
S
A
E
Q
R
Site 26
Y419
P
G
V
C
F
R
L
Y
A
E
S
D
Y
D
A
Site 27
S422
C
F
R
L
Y
A
E
S
D
Y
D
A
F
A
P
Site 28
Y424
R
L
Y
A
E
S
D
Y
D
A
F
A
P
Y
P
Site 29
Y430
D
Y
D
A
F
A
P
Y
P
V
P
E
I
R
R
Site 30
S449
S
L
V
L
Q
M
K
S
M
S
V
G
D
P
R
Site 31
S451
V
L
Q
M
K
S
M
S
V
G
D
P
R
T
F
Site 32
T457
M
S
V
G
D
P
R
T
F
P
F
I
E
P
P
Site 33
S484
R
D
Q
G
A
L
D
S
S
E
A
L
T
P
I
Site 34
S485
D
Q
G
A
L
D
S
S
E
A
L
T
P
I
G
Site 35
S531
A
A
A
L
S
V
Q
S
P
F
T
R
S
A
Q
Site 36
T534
L
S
V
Q
S
P
F
T
R
S
A
Q
S
S
P
Site 37
S536
V
Q
S
P
F
T
R
S
A
Q
S
S
P
E
C
Site 38
S540
F
T
R
S
A
Q
S
S
P
E
C
C
T
P
P
Site 39
T545
Q
S
S
P
E
C
C
T
P
P
A
S
S
L
A
Site 40
S549
E
C
C
T
P
P
A
S
S
L
A
A
P
R
C
Site 41
T558
L
A
A
P
R
C
C
T
H
R
S
W
R
P
A
Site 42
T566
H
R
S
W
R
P
A
T
A
T
E
A
E
T
T
Site 43
T568
S
W
R
P
A
T
A
T
E
A
E
T
T
R
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation