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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM14
Full Name:
Tripartite motif-containing protein 14
Alias:
TRI14; Tripartite motif-containing 14
Type:
Transcription regulation
Mass (Da):
49773
Number AA:
442
UniProt ID:
Q14142
International Prot ID:
IsofromAlpha - IPI00028976
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
G
A
A
T
G
S
R
T
P
G
R
S
E
Site 2
T10
G
A
A
T
G
S
R
T
P
G
R
S
E
L
V
Site 3
S14
G
S
R
T
P
G
R
S
E
L
V
E
G
C
G
Site 4
S72
A
V
H
V
Q
K
L
S
Q
E
C
L
K
Q
L
Site 5
S107
L
K
A
N
A
E
S
S
K
T
W
L
K
G
K
Site 6
T109
A
N
A
E
S
S
K
T
W
L
K
G
K
F
T
Site 7
T116
T
W
L
K
G
K
F
T
E
L
R
L
L
L
D
Site 8
Y144
T
Q
L
T
L
Q
V
Y
R
E
Q
A
D
S
C
Site 9
S150
V
Y
R
E
Q
A
D
S
C
R
E
Q
L
D
I
Site 10
S167
D
L
S
N
R
V
W
S
I
S
Q
E
P
D
P
Site 11
S169
S
N
R
V
W
S
I
S
Q
E
P
D
P
V
Q
Site 12
S193
Q
E
M
Q
Q
Q
M
S
L
G
E
L
C
H
P
Site 13
T225
A
V
E
S
T
L
Q
T
P
L
D
I
R
L
K
Site 14
S240
E
S
I
N
C
Q
L
S
D
P
S
S
T
K
P
Site 15
S244
C
Q
L
S
D
P
S
S
T
K
P
G
T
L
L
Site 16
T249
P
S
S
T
K
P
G
T
L
L
K
T
S
P
S
Site 17
S254
P
G
T
L
L
K
T
S
P
S
P
E
R
S
L
Site 18
S256
T
L
L
K
T
S
P
S
P
E
R
S
L
L
L
Site 19
S260
T
S
P
S
P
E
R
S
L
L
L
K
Y
A
R
Site 20
Y265
E
R
S
L
L
L
K
Y
A
R
T
P
T
L
D
Site 21
T268
L
L
L
K
Y
A
R
T
P
T
L
D
P
D
T
Site 22
T270
L
K
Y
A
R
T
P
T
L
D
P
D
T
M
H
Site 23
T275
T
P
T
L
D
P
D
T
M
H
A
R
L
R
L
Site 24
S283
M
H
A
R
L
R
L
S
A
D
R
L
T
V
R
Site 25
Y323
C
F
A
T
G
R
H
Y
W
E
V
D
V
Q
E
Site 26
S343
W
V
G
A
A
Y
A
S
L
R
R
R
G
A
S
Site 27
S350
S
L
R
R
R
G
A
S
A
A
A
R
L
G
C
Site 28
Y371
L
K
R
Y
D
L
E
Y
W
A
F
H
D
G
Q
Site 29
S380
A
F
H
D
G
Q
R
S
R
L
R
P
R
D
D
Site 30
T416
G
G
M
S
H
L
H
T
F
R
A
T
F
Q
E
Site 31
T420
H
L
H
T
F
R
A
T
F
Q
E
P
L
Y
P
Site 32
Y426
A
T
F
Q
E
P
L
Y
P
A
L
R
L
W
E
Site 33
S437
R
L
W
E
G
A
I
S
I
P
R
L
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation