PhosphoNET

           
Protein Info 
   
Short Name:  TOB2
Full Name:  Protein Tob2
Alias:  Tob4; Tobl; Transducer of erbb2, 2; Trob2
Type:  Cytoplasm, Nucleus protein
Mass (Da):  36632
Number AA:  344
UniProt ID:  Q14106
International Prot ID:  IPI00028889
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0007292  GO:0008285   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S14VALNFIISYLYNKLP
Site 2Y40ERLLKKKYEGHWYPE
Site 3Y45KKYEGHWYPEKPLKG
Site 4S53PEKPLKGSGFRCVHI
Site 5S91ANVPEELSVWIDPFE
Site 6Y113KGAVKVLYLDDSEGC
Site 7S117KVLYLDDSEGCGAPE
Site 8S132LDKEIKSSFNPDAQV
Site 9S145QVFVPIGSQDSSLSN
Site 10S148VPIGSQDSSLSNSPS
Site 11S149PIGSQDSSLSNSPSP
Site 12S151GSQDSSLSNSPSPSF
Site 13S153QDSSLSNSPSPSFGQ
Site 14S155SSLSNSPSPSFGQSP
Site 15S157LSNSPSPSFGQSPSP
Site 16S161PSPSFGQSPSPTFIP
Site 17S163PSFGQSPSPTFIPRS
Site 18T165FGQSPSPTFIPRSAQ
Site 19S170SPTFIPRSAQPITFT
Site 20T175PRSAQPITFTTASFA
Site 21T184TTASFAATKFGSTKM
Site 22S199KKGGGAASGGGVASS
Site 23S205ASGGGVASSGAGGQQ
Site 24S206SGGGVASSGAGGQQP
Site 25S222QQPRMARSPTNSLLK
Site 26T224PRMARSPTNSLLKHK
Site 27S226MARSPTNSLLKHKSL
Site 28S232NSLLKHKSLSLSMHS
Site 29S234LLKHKSLSLSMHSLN
Site 30S236KHKSLSLSMHSLNFI
Site 31T244MHSLNFITANPAPQS
Site 32S251TANPAPQSQLSPNAK
Site 33S254PAPQSQLSPNAKEFV
Site 34Y262PNAKEFVYNGGGSPS
Site 35S269YNGGGSPSLFFDAAD
Site 36S280DAADGQGSGTPGPFG
Site 37T282ADGQGSGTPGPFGGS
Site 38S289TPGPFGGSGAGTCNS
Site 39T293FGGSGAGTCNSSSFD
Site 40S296SGAGTCNSSSFDMAQ
Site 41T317NSLFLEKTPFVEGLS
Site 42S324TPFVEGLSYNLNTMQ
Site 43Y325PFVEGLSYNLNTMQY
Site 44Y332YNLNTMQYPSQQFQP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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