KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CYLC2
Full Name:
Cylicin-2
Alias:
CYL2; Cylicin II; Cylicin, basic protein of sperm head cytoskeleton 2; Multiple-band polypeptide II
Type:
Cytoskeletal protein
Mass (Da):
39079
Number AA:
348
UniProt ID:
Q14093
International Prot ID:
IPI00028539
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0033150
Uniprot
OncoNet
Molecular Function:
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
Q
R
V
N
F
G
P
Y
D
N
Y
I
P
V
S
Site 2
Y17
N
F
G
P
Y
D
N
Y
I
P
V
S
E
L
S
Site 3
S21
Y
D
N
Y
I
P
V
S
E
L
S
K
K
S
W
Site 4
S24
Y
I
P
V
S
E
L
S
K
K
S
W
N
Q
Q
Site 5
S27
V
S
E
L
S
K
K
S
W
N
Q
Q
H
F
A
Site 6
T45
P
K
P
Q
R
P
G
T
K
R
R
S
K
P
S
Site 7
S49
R
P
G
T
K
R
R
S
K
P
S
Q
I
R
D
Site 8
S52
T
K
R
R
S
K
P
S
Q
I
R
D
N
T
V
Site 9
T58
P
S
Q
I
R
D
N
T
V
S
I
I
D
E
E
Site 10
S60
Q
I
R
D
N
T
V
S
I
I
D
E
E
Q
L
Site 11
Y78
R
R
Q
P
L
W
M
Y
R
S
L
M
R
I
S
Site 12
S80
Q
P
L
W
M
Y
R
S
L
M
R
I
S
E
R
Site 13
S85
Y
R
S
L
M
R
I
S
E
R
P
S
V
Y
L
Site 14
S89
M
R
I
S
E
R
P
S
V
Y
L
A
A
R
R
Site 15
T104
Q
P
L
K
P
T
R
T
V
E
V
D
S
K
A
Site 16
T122
G
K
K
G
E
D
K
T
T
Q
K
D
T
T
D
Site 17
T123
K
K
G
E
D
K
T
T
Q
K
D
T
T
D
S
Site 18
T127
D
K
T
T
Q
K
D
T
T
D
S
E
S
E
L
Site 19
T128
K
T
T
Q
K
D
T
T
D
S
E
S
E
L
K
Site 20
S130
T
Q
K
D
T
T
D
S
E
S
E
L
K
Q
G
Site 21
S132
K
D
T
T
D
S
E
S
E
L
K
Q
G
K
K
Site 22
S141
L
K
Q
G
K
K
D
S
K
K
G
K
D
I
E
Site 23
S161
K
L
D
A
K
K
D
S
K
K
G
K
K
D
A
Site 24
S174
D
A
E
K
G
K
D
S
A
T
E
S
E
D
E
Site 25
T176
E
K
G
K
D
S
A
T
E
S
E
D
E
K
G
Site 26
S178
G
K
D
S
A
T
E
S
E
D
E
K
G
G
A
Site 27
S202
D
S
N
K
G
K
D
S
A
T
E
S
E
G
E
Site 28
T204
N
K
G
K
D
S
A
T
E
S
E
G
E
K
G
Site 29
S206
G
K
D
S
A
T
E
S
E
G
E
K
G
G
T
Site 30
T213
S
E
G
E
K
G
G
T
E
K
D
S
K
K
G
Site 31
S217
K
G
G
T
E
K
D
S
K
K
G
K
K
D
S
Site 32
S224
S
K
K
G
K
K
D
S
K
K
G
K
D
S
A
Site 33
S230
D
S
K
K
G
K
D
S
A
I
E
L
Q
A
V
Site 34
S278
K
K
D
K
K
K
P
S
S
T
D
S
D
S
K
Site 35
S279
K
D
K
K
K
P
S
S
T
D
S
D
S
K
D
Site 36
T280
D
K
K
K
P
S
S
T
D
S
D
S
K
D
D
Site 37
S282
K
K
P
S
S
T
D
S
D
S
K
D
D
V
K
Site 38
S284
P
S
S
T
D
S
D
S
K
D
D
V
K
K
E
Site 39
T297
K
E
S
K
K
D
A
T
K
D
A
K
K
V
A
Site 40
T308
K
K
V
A
K
K
D
T
E
K
E
S
A
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation