KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CNGB1
Full Name:
Cyclic nucleotide-gated cation channel beta-1
Alias:
CNCG2; CNCG3L; CNCG4; CNG channel 4; CNG4; CNG-4; CNGB1B; Cyclic nucleotide gated channel beta 1; Cyclic nucleotide-gated cation channel modulatory subunit; GAR1; GARP; RCNC2; RCNCb
Type:
Channel protein
Mass (Da):
102285
Number AA:
909
UniProt ID:
Q14028
International Prot ID:
IPI00297656
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0017071
Uniprot
OncoNet
Molecular Function:
GO:0030552
GO:0005222
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007608
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
V
L
P
Q
P
P
G
T
P
R
K
T
K
M
Q
Site 2
T19
P
P
G
T
P
R
K
T
K
M
Q
E
E
E
E
Site 3
T48
P
N
P
E
E
A
E
T
E
S
E
S
M
P
P
Site 4
S50
P
E
E
A
E
T
E
S
E
S
M
P
P
E
E
Site 5
S52
E
A
E
T
E
S
E
S
M
P
P
E
E
S
F
Site 6
S58
E
S
M
P
P
E
E
S
F
K
E
E
E
V
A
Site 7
S70
E
V
A
V
A
D
P
S
P
Q
E
T
K
E
A
Site 8
T74
A
D
P
S
P
Q
E
T
K
E
A
A
L
T
S
Site 9
T80
E
T
K
E
A
A
L
T
S
T
I
S
L
R
A
Site 10
S93
R
A
Q
G
A
E
I
S
E
M
N
S
P
S
R
Site 11
S97
A
E
I
S
E
M
N
S
P
S
R
R
V
L
T
Site 12
S99
I
S
E
M
N
S
P
S
R
R
V
L
T
W
L
Site 13
T104
S
P
S
R
R
V
L
T
W
L
M
K
G
V
E
Site 14
S120
V
I
P
Q
P
V
H
S
I
T
E
D
P
A
Q
Site 15
T122
P
Q
P
V
H
S
I
T
E
D
P
A
Q
I
L
Site 16
S133
A
Q
I
L
G
H
G
S
T
G
D
T
G
C
T
Site 17
T137
G
H
G
S
T
G
D
T
G
C
T
D
E
P
N
Site 18
T140
S
T
G
D
T
G
C
T
D
E
P
N
E
A
L
Site 19
T152
E
A
L
E
A
Q
D
T
R
P
G
L
R
L
L
Site 20
S176
V
L
P
Q
P
P
K
S
S
E
V
W
R
D
E
Site 21
S192
A
V
A
T
G
A
A
S
D
P
A
P
P
G
R
Site 22
T212
P
K
L
Q
A
R
E
T
P
S
L
P
T
P
I
Site 23
T217
R
E
T
P
S
L
P
T
P
I
P
L
Q
P
K
Site 24
S239
A
P
E
P
Q
P
G
S
Q
A
Q
T
S
S
L
Site 25
T243
Q
P
G
S
Q
A
Q
T
S
S
L
P
P
T
R
Site 26
S244
P
G
S
Q
A
Q
T
S
S
L
P
P
T
R
D
Site 27
S245
G
S
Q
A
Q
T
S
S
L
P
P
T
R
D
P
Site 28
T249
Q
T
S
S
L
P
P
T
R
D
P
A
R
L
V
Site 29
S283
I
G
E
Q
E
P
D
S
P
G
I
C
D
V
Q
Site 30
S321
E
D
A
H
Q
D
V
S
T
S
P
Q
G
T
E
Site 31
S323
A
H
Q
D
V
S
T
S
P
Q
G
T
E
V
V
Site 32
T327
V
S
T
S
P
Q
G
T
E
V
V
P
A
Y
E
Site 33
Y333
G
T
E
V
V
P
A
Y
E
E
E
N
K
A
V
Site 34
S348
E
K
M
P
R
E
L
S
R
I
E
E
E
K
E
Site 35
T373
E
E
E
E
E
E
V
T
E
V
L
L
D
S
C
Site 36
S390
S
Q
V
G
V
G
Q
S
E
E
D
G
T
R
P
Site 37
T395
G
Q
S
E
E
D
G
T
R
P
Q
S
T
S
D
Site 38
S399
E
D
G
T
R
P
Q
S
T
S
D
Q
K
L
W
Site 39
S401
G
T
R
P
Q
S
T
S
D
Q
K
L
W
E
E
Site 40
S456
A
E
A
E
A
A
S
S
G
V
P
A
T
K
Q
Site 41
T472
P
E
V
Q
V
E
D
T
D
A
D
S
C
P
L
Site 42
S476
V
E
D
T
D
A
D
S
C
P
L
M
A
E
E
Site 43
S487
M
A
E
E
N
P
P
S
T
V
L
P
P
P
S
Site 44
T488
A
E
E
N
P
P
S
T
V
L
P
P
P
S
P
Site 45
S494
S
T
V
L
P
P
P
S
P
A
K
S
D
T
L
Site 46
S498
P
P
P
S
P
A
K
S
D
T
L
I
V
P
S
Site 47
T500
P
S
P
A
K
S
D
T
L
I
V
P
S
S
A
Site 48
S505
S
D
T
L
I
V
P
S
S
A
S
G
T
H
R
Site 49
S506
D
T
L
I
V
P
S
S
A
S
G
T
H
R
K
Site 50
T510
V
P
S
S
A
S
G
T
H
R
K
K
L
P
S
Site 51
S517
T
H
R
K
K
L
P
S
E
D
D
E
A
E
E
Site 52
S533
K
A
L
S
P
A
E
S
P
V
V
A
W
S
D
Site 53
S539
E
S
P
V
V
A
W
S
D
P
T
T
P
K
D
Site 54
T543
V
A
W
S
D
P
T
T
P
K
D
T
D
G
Q
Site 55
S555
D
G
Q
D
R
A
A
S
T
A
S
T
N
S
A
Site 56
T559
R
A
A
S
T
A
S
T
N
S
A
I
I
N
D
Site 57
T592
K
L
I
D
P
D
V
T
S
D
E
E
S
P
K
Site 58
S593
L
I
D
P
D
V
T
S
D
E
E
S
P
K
P
Site 59
S597
D
V
T
S
D
E
E
S
P
K
P
S
P
A
K
Site 60
S601
D
E
E
S
P
K
P
S
P
A
K
K
A
P
E
Site 61
T613
A
P
E
P
A
P
D
T
K
P
A
E
A
E
P
Site 62
Y626
E
P
V
E
E
E
H
Y
C
D
M
L
C
C
K
Site 63
Y642
K
H
R
P
W
K
K
Y
Q
F
P
Q
S
I
D
Site 64
S647
K
K
Y
Q
F
P
Q
S
I
D
P
L
T
N
L
Site 65
Y682
P
V
R
W
A
F
P
Y
Q
T
P
D
N
I
H
Site 66
T723
V
R
G
G
D
I
I
T
D
K
K
D
M
R
N
Site 67
Y732
K
K
D
M
R
N
N
Y
L
K
S
R
R
F
K
Site 68
Y769
R
L
P
R
C
L
K
Y
M
A
F
F
E
F
N
Site 69
S781
E
F
N
S
R
L
E
S
I
L
S
K
A
Y
V
Site 70
S784
S
R
L
E
S
I
L
S
K
A
Y
V
Y
R
V
Site 71
Y787
E
S
I
L
S
K
A
Y
V
Y
R
V
I
R
T
Site 72
Y809
L
H
L
N
S
C
L
Y
Y
W
A
S
A
Y
Q
Site 73
Y810
H
L
N
S
C
L
Y
Y
W
A
S
A
Y
Q
G
Site 74
Y815
L
Y
Y
W
A
S
A
Y
Q
G
L
G
S
T
H
Site 75
Y825
L
G
S
T
H
W
V
Y
D
G
V
G
N
S
Y
Site 76
Y832
Y
D
G
V
G
N
S
Y
I
R
C
Y
Y
F
A
Site 77
Y892
A
A
T
A
G
Q
T
Y
Y
R
S
C
M
D
S
Site 78
Y893
A
T
A
G
Q
T
Y
Y
R
S
C
M
D
S
T
Site 79
S895
A
G
Q
T
Y
Y
R
S
C
M
D
S
T
V
K
Site 80
S899
Y
Y
R
S
C
M
D
S
T
V
K
Y
M
N
F
Site 81
Y903
C
M
D
S
T
V
K
Y
M
N
F
Y
K
I
P
Site 82
Y907
T
V
K
Y
M
N
F
Y
K
I
P
K
S
V
Q
Site 83
S912
N
F
Y
K
I
P
K
S
V
Q
N
R
V
K
T
Site 84
S934
S
Q
G
M
L
D
E
S
E
L
M
V
Q
L
P
Site 85
S980
D
M
L
K
R
L
R
S
V
V
Y
L
P
N
D
Site 86
Y983
K
R
L
R
S
V
V
Y
L
P
N
D
Y
V
C
Site 87
Y988
V
V
Y
L
P
N
D
Y
V
C
K
K
G
E
I
Site 88
Y1000
G
E
I
G
R
E
M
Y
I
I
Q
A
G
Q
V
Site 89
T1043
V
G
G
G
N
R
R
T
A
N
V
V
A
H
G
Site 90
Y1069
L
N
E
I
L
V
H
Y
P
E
S
Q
K
L
L
Site 91
S1072
I
L
V
H
Y
P
E
S
Q
K
L
L
R
K
K
Site 92
S1086
K
A
R
R
M
L
R
S
N
N
K
P
K
E
E
Site 93
S1095
N
K
P
K
E
E
K
S
V
L
I
L
P
P
R
Site 94
S1157
E
L
V
E
Q
A
K
S
S
Q
D
V
K
G
E
Site 95
S1158
L
V
E
Q
A
K
S
S
Q
D
V
K
G
E
E
Site 96
S1167
D
V
K
G
E
E
G
S
A
A
P
D
Q
H
T
Site 97
T1174
S
A
A
P
D
Q
H
T
H
P
K
E
A
A
T
Site 98
T1181
T
H
P
K
E
A
A
T
D
P
P
A
P
R
T
Site 99
T1188
T
D
P
P
A
P
R
T
P
P
E
P
P
G
S
Site 100
S1195
T
P
P
E
P
P
G
S
P
P
S
S
P
P
P
Site 101
S1198
E
P
P
G
S
P
P
S
S
P
P
P
A
S
L
Site 102
S1199
P
P
G
S
P
P
S
S
P
P
P
A
S
L
G
Site 103
S1204
P
S
S
P
P
P
A
S
L
G
R
P
E
G
E
Site 104
S1222
P
A
E
P
E
E
H
S
V
R
I
C
M
S
P
Site 105
S1228
H
S
V
R
I
C
M
S
P
G
P
E
P
G
E
Site 106
S1239
E
P
G
E
Q
I
L
S
V
K
M
P
E
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation