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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CUX1
Full Name:
Protein CASP
Alias:
CUTL1; Homeobox protein cut-like 1
Type:
Mass (Da):
77455
Number AA:
678
UniProt ID:
Q13948
International Prot ID:
IPI00071696
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030173
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006891
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
N
V
G
S
M
F
Q
Y
W
K
R
F
D
L
Q
Site 2
T27
L
Q
R
E
L
D
A
T
A
T
V
L
A
N
R
Site 3
T29
R
E
L
D
A
T
A
T
V
L
A
N
R
Q
D
Site 4
S41
R
Q
D
E
S
E
Q
S
R
K
R
L
I
E
Q
Site 5
S49
R
K
R
L
I
E
Q
S
R
E
F
K
K
N
T
Site 6
T56
S
R
E
F
K
K
N
T
P
E
D
L
R
K
Q
Site 7
S79
Q
G
E
I
D
A
L
S
K
R
S
K
E
A
E
Site 8
T124
Q
R
L
H
D
I
E
T
E
N
Q
K
L
R
E
Site 9
T132
E
N
Q
K
L
R
E
T
L
E
E
Y
N
K
E
Site 10
Y160
L
K
E
K
I
R
E
Y
E
Q
T
L
K
N
Q
Site 11
T163
K
I
R
E
Y
E
Q
T
L
K
N
Q
A
E
T
Site 12
T193
K
E
R
K
L
Q
E
T
Q
M
S
T
T
S
K
Site 13
S196
K
L
Q
E
T
Q
M
S
T
T
S
K
L
E
E
Site 14
T220
T
A
L
E
K
T
R
T
E
L
F
D
L
K
T
Site 15
T227
T
E
L
F
D
L
K
T
K
Y
D
E
E
T
T
Site 16
Y229
L
F
D
L
K
T
K
Y
D
E
E
T
T
A
K
Site 17
T245
D
E
I
E
M
I
M
T
D
L
E
R
A
N
Q
Site 18
T263
V
A
Q
R
E
A
E
T
L
R
E
Q
L
S
S
Site 19
S269
E
T
L
R
E
Q
L
S
S
A
N
H
S
L
Q
Site 20
S270
T
L
R
E
Q
L
S
S
A
N
H
S
L
Q
L
Site 21
S274
Q
L
S
S
A
N
H
S
L
Q
L
A
S
Q
I
Site 22
S323
D
V
Q
R
L
Q
A
S
L
T
K
L
R
E
N
Site 23
T325
Q
R
L
Q
A
S
L
T
K
L
R
E
N
S
A
Site 24
S331
L
T
K
L
R
E
N
S
A
S
Q
I
S
Q
L
Site 25
S333
K
L
R
E
N
S
A
S
Q
I
S
Q
L
E
Q
Site 26
S343
S
Q
L
E
Q
Q
L
S
A
K
N
S
T
L
K
Site 27
S347
Q
Q
L
S
A
K
N
S
T
L
K
Q
L
E
E
Site 28
Y362
K
L
K
G
Q
A
D
Y
E
E
V
K
K
E
L
Site 29
S374
K
E
L
N
I
L
K
S
M
E
F
A
P
S
E
Site 30
S380
K
S
M
E
F
A
P
S
E
G
A
G
T
Q
D
Site 31
T385
A
P
S
E
G
A
G
T
Q
D
A
A
K
P
L
Site 32
S402
L
L
L
E
K
N
R
S
L
Q
S
E
N
A
A
Site 33
S413
E
N
A
A
L
R
I
S
N
S
D
L
S
G
R
Site 34
S415
A
A
L
R
I
S
N
S
D
L
S
G
R
C
A
Site 35
S418
R
I
S
N
S
D
L
S
G
R
C
A
E
L
Q
Site 36
T434
R
I
T
E
A
V
A
T
A
T
E
Q
R
E
L
Site 37
S450
A
R
L
E
Q
D
L
S
I
I
Q
S
I
Q
R
Site 38
S454
Q
D
L
S
I
I
Q
S
I
Q
R
P
D
A
E
Site 39
S490
Y
G
P
A
A
P
A
S
G
A
L
P
E
G
Q
Site 40
S500
L
P
E
G
Q
V
D
S
L
L
S
I
I
S
S
Site 41
S503
G
Q
V
D
S
L
L
S
I
I
S
S
Q
R
E
Site 42
S506
D
S
L
L
S
I
I
S
S
Q
R
E
R
F
R
Site 43
S507
S
L
L
S
I
I
S
S
Q
R
E
R
F
R
A
Site 44
T529
E
N
R
L
A
Q
H
T
L
Q
A
L
Q
S
E
Site 45
S535
H
T
L
Q
A
L
Q
S
E
L
D
S
L
R
A
Site 46
S539
A
L
Q
S
E
L
D
S
L
R
A
D
N
I
K
Site 47
S556
E
K
I
K
F
L
Q
S
Y
P
G
R
G
S
G
Site 48
Y557
K
I
K
F
L
Q
S
Y
P
G
R
G
S
G
S
Site 49
S562
Q
S
Y
P
G
R
G
S
G
S
D
D
T
E
L
Site 50
S564
Y
P
G
R
G
S
G
S
D
D
T
E
L
R
Y
Site 51
T567
R
G
S
G
S
D
D
T
E
L
R
Y
S
S
Q
Site 52
Y571
S
D
D
T
E
L
R
Y
S
S
Q
Y
E
E
R
Site 53
S572
D
D
T
E
L
R
Y
S
S
Q
Y
E
E
R
L
Site 54
S573
D
T
E
L
R
Y
S
S
Q
Y
E
E
R
L
D
Site 55
Y575
E
L
R
Y
S
S
Q
Y
E
E
R
L
D
P
F
Site 56
S583
E
E
R
L
D
P
F
S
S
F
S
K
R
E
R
Site 57
S584
E
R
L
D
P
F
S
S
F
S
K
R
E
R
Q
Site 58
S586
L
D
P
F
S
S
F
S
K
R
E
R
Q
R
K
Site 59
Y594
K
R
E
R
Q
R
K
Y
L
S
L
S
P
W
D
Site 60
S596
E
R
Q
R
K
Y
L
S
L
S
P
W
D
K
A
Site 61
S598
Q
R
K
Y
L
S
L
S
P
W
D
K
A
T
L
Site 62
S644
Y
K
L
A
W
S
E
S
M
E
R
D
C
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation